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Feature Channels: Clinical Trials

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Newswise: Rutgers School of Dental Medicine Dean Is Recognized for Her Visionary Leadership
Released: 1-Apr-2025 8:20 PM EDT
Rutgers School of Dental Medicine Dean Is Recognized for Her Visionary Leadership
Rutgers University-New Brunswick

Cecile A. Feldman is honored by the American Dental Education Association’s Gies Foundation for being transformative for dental education

Newswise: Clinical Researchers Aim to Improve Breast Cancer Outcomes Through Sustainable and Effective Weight Loss in the FITWISE study
Released: 1-Apr-2025 8:00 PM EDT
Clinical Researchers Aim to Improve Breast Cancer Outcomes Through Sustainable and Effective Weight Loss in the FITWISE study
Rutgers Cancer Institute

Learn more about FITWISE at RWJBarnabas Health and Rutgers Cancer Institute, an innovative clinical trial aiming to induce sustainable weight loss, improve cardiometabolic health and potentially reduce cancer recurrence during the survivorship years of patients with early-stage hormone receptor positive/Her 2 negative (HR+/Her2-) breast cancer.

Released: 31-Mar-2025 7:15 PM EDT
باحثو مايو كلينك يدرسون أسباب الخَرَف سريع التقدم
Mayo Clinic

يواجه أغلب مرضى داء الزهايمر والخَرَف المرتبط بداء الزهايمر الظهور والتقدم التدريجين للأعراض الإدراكية، مما يسبب التدهور على مدى سنوات أو عقود. إلا أنه في مجموعة فرعية صغيرة من المرضى تبدأ الأعراض سريعًا، مؤديةً إلى الإصابة بالخَرَف في غضون سنة واحدة والعجز الكامل خلال سنتين من بداية ظهور الأعراض. وتطمح دراسة جديدة تُجرى في مايو كلينك إلى تحديد سبب إصابة مرضى داء الزهايمر والخَرَف المرتبط بداء الزهايمر بهذا الخَرَف سريع التقدم.

Released: 31-Mar-2025 7:15 PM EDT
Pesquisadores da Mayo Clinic estudam as causas da demência rapidamente progressiva
Mayo Clinic

A maioria dos pacientes com doença de Alzheimer (DA) e demências relacionadas à doença de Alzheimer (DRDA) experimenta o início gradual e a progressão dos sintomas cognitivos, levando-os ao declínio ao longo dos anos ou das décadas. No entanto, em um pequeno subconjunto de pacientes, os sintomas começam rapidamente, levando à demência dentro de um ano e à incapacidade total dentro de dois anos após o início dos sintomas. Um novo estudo na Mayo Clinic tem como objetivo determinar por que pacientes com a doença de Alzheimer e DRDA desenvolvem essa demência rapidamente progressiva (DRP).

Released: 31-Mar-2025 7:15 PM EDT
Investigadores de Mayo Clinic estudian las causas de la demencia rápidamente progresiva
Mayo Clinic

La mayoría de los pacientes con enfermedad de Alzheimer (EA) y enfermedad de alzheimer y las demencias relacionadas (DRDA, por sus siglas en inglés) experimenta el inicio gradual y la progresión de los síntomas cognitivos, lo que los lleva al deterioro a lo largo de los años o décadas. Sin embargo, en un pequeño subconjunto de pacientes, los síntomas comienzan rápidamente, lo que lleva a la demencia dentro de un año y a la discapacidad total dentro de los dos años posteriores al inicio de los síntomas. Un nuevo estudio en Mayo Clinic tiene como objetivo determinar por qué los pacientes con la enfermedad de Alzheimer y DRDA desarrollan esta demencia rápidamente progresiva (DRP).

Newswise: Intravascular Imaging Can Improve Outcomes for Complex Stenting Procedures in Patients with High-Risk Calcified Coronary Artery Disease
Released: 31-Mar-2025 2:25 PM EDT
Intravascular Imaging Can Improve Outcomes for Complex Stenting Procedures in Patients with High-Risk Calcified Coronary Artery Disease
Mount Sinai Health System

Study led by Mount Sinai researcher could lead to more widespread use of imaging technique to improve survival and prevent complications

Released: 31-Mar-2025 10:45 AM EDT
UTSW Research: Mosquito Saliva and Malaria, Brain Tumors, and More
UT Southwestern Medical Center

Malaria, responsible for hundreds of thousands of deaths each year worldwide, is caused by a parasite transmitted through the salivary glands of female Anopheles mosquitoes. Understanding the biology of these tissues is critical to developing new treatments for the disease, found mostly in tropical countries.

Newswise: Long-Term Data Supports Aspherical Lenslets as Effective Myopia Control in Kids
Released: 31-Mar-2025 9:30 AM EDT
Long-Term Data Supports Aspherical Lenslets as Effective Myopia Control in Kids
Chinese Academy of Sciences

A landmark five-year clinical study has revealed that spectacle lenses equipped with highly aspherical lenslets (HAL) can significantly slow the progression of myopia and axial elongation in children. Compared to an extrapolated control group, HAL lenses reduced myopia progression by 1.75 diopters (D) and axial elongation by 0.72 mm, effectively lowering the risk of developing high myopia (−6.00 D or worse) by fourfold. These findings mark a critical advancement in long-term myopia management, offering a safe and non-invasive intervention amid a growing global vision crisis. With nearly half the world’s population projected to be myopic by 2050, HAL lenses may hold the key to preventing serious complications such as retinal detachment and glaucoma.

Released: 31-Mar-2025 8:00 AM EDT
Mayo Clinic Researchers Study Causes of Rapidly Progressive Dementia
Mayo Clinic

Most patients with Alzheimer's disease and Alzheimer's Disease Related Dementias (ADRD) experience the gradual onset and progression of cognitive symptoms, leading to decline over years or decades. However, in a small subset of patients, symptoms begin rapidly, leading to dementia within one year and complete incapacitation within two years of symptom onset.

Newswise: Electronic Provider Alerts Improve Treatment Rates of Valvular Heart Disease
Released: 30-Mar-2025 2:30 PM EDT
Electronic Provider Alerts Improve Treatment Rates of Valvular Heart Disease
University of California, San Francisco (UCSF)

A new method of alerting clinical care providers holds promise for increasing treatment and improving survival for patients with severe aortic stenosis (AS), a valvular heart condition that can be deadly when left untreated. Researchers from UC San Francisco (UCSF) and Mass General Brigham found that electronic messages sent to providers within one week of patients receiving an echocardiogram improved care for patients with severe AS — including higher rates of treatment with aortic valve replacement (AVR), particularly in symptomatic patients.

Newswise: Monoclonal Antibody Can Reverse Effects of Bleeding and Complications Linked to Common Medication for Heart Attacks
Released: 29-Mar-2025 12:45 PM EDT
Monoclonal Antibody Can Reverse Effects of Bleeding and Complications Linked to Common Medication for Heart Attacks
Mount Sinai Health System

Trial led by Mount Sinai researcher could save lives for patients in need of urgent surgery, invasive procedures, or experiencing major bleeding

Released: 28-Mar-2025 8:05 PM EDT
AACI Statement on Continued Reductions in Force
Association of American Cancer Institutes (AACI)

The Association of American Cancer Institutes (AACI) remains strongly opposed to the indiscriminate firing of dedicated public servants across the federal government.

Released: 28-Mar-2025 7:35 PM EDT
Exercise Helps Colon Cancer Survivors Live Longer
Dana-Farber Cancer Institute

Regular physical activity after treatment for stage 3 colon cancer reduces and may even eliminate disparities in survival between those with cancer and those in a general population of similar age and sex, according to new Dana-Farber Cancer Institute research.

Newswise: UniSA-Led Study Tackles Medication Risks in Aged Care Homes
Released: 28-Mar-2025 12:00 PM EDT
UniSA-Led Study Tackles Medication Risks in Aged Care Homes
University of South Australia

As Australia undertakes major aged care reforms to improve medication management and resident safety, a new University of South Australia initiative will trial medication safety rou...

Newswise: Baltimore Student-Athlete Is Winning Match Against Multiple Sclerosis
Released: 27-Mar-2025 6:05 PM EDT
Baltimore Student-Athlete Is Winning Match Against Multiple Sclerosis
Johns Hopkins Medicine

Gabryelle “Gabby” Scholfield, a 16-year-old student-athlete at Edmondson Westside High School in Baltimore, who plays center on her basketball team, is known for getting rebounds on the basketball court. However, only about a year ago, she was rebounding from serious complications of multiple sclerosis (MS).

Released: 27-Mar-2025 10:20 AM EDT
Engenheiros de manufatura da Mayo Clinic estão prestes a entregar novas bioterapias
Mayo Clinic

Engenheiros de manufatura estão na vanguarda de trazer novos medicamentos derivados de fontes humanas, como células, sangue e genes, para os pacientes. Eles produzem o que muitas vezes são bioterapias pioneiras do seu tipo para doenças que anteriormente tinham poucas ou nenhuma opção de tratamento.

   
Released: 27-Mar-2025 9:45 AM EDT
Mayo Clinic Manufacturing Engineers on the Cusp of Delivering New Biotherapies
Mayo Clinic

Manufacturing engineers are at the forefront of bringing new medicines derived from human sources such as cells, blood and genes to patients. They produce what are often first-of-their kind biotherapies for diseases that previously had few or no treatment options.

   
Released: 27-Mar-2025 9:15 AM EDT
Ingenieros de manufactura de Mayo Clinic están a punto de entregar nuevas bioterapias
Mayo Clinic

JACKSONVILLE, Florida — Ingenieros de manufactura están a la vanguardia de llevar nuevos medicamentos derivados de fuentes humanas, como células, sangre y genes, a los pacientes. Ellos producen lo que a menudo son bioterapias pioneras de su tipo para enfermedades que anteriormente tenían pocas o ninguna opción de tratamiento.

   
Released: 27-Mar-2025 8:20 AM EDT
NIH-Funded Trial Studies if Wearables Can Reduce the Need for Continuous Blood Thinners for Patients with Atrial Fibrillation
Northwestern Medicine

Atrial fibrillation (AFib) is the most common type of heart arrhythmia impacting more than 5 million people in the United States, a number that is anticipated to reach 12.1 million by 2030. The heart rhythm condition is characterized by fast and irregular heartbeats from the upper chambers of the heart. People with AFib are at increased risk of stroke, heart failure, dementia, and premature death.

Released: 27-Mar-2025 12:05 AM EDT
مهندسو التصنيع في مايو كلينك على أعتاب تقديم علاجات حيوية جديدة
Mayo Clinic

جاكسونفيل، ولاية فلوريدا — يحتل مهندسو التصنيع الصدارة في جلب الأدوية الجديدة المشتقة من مصادر بشرية، مثل الخلايا والدم والجينات، للمرضى. وينتجون علاجات حيوية غالبًا ما تكون الأولى من نوعها لأمراض لم يكن لها في السابق سوى خيارات علاجية محدودة أو لم يكن لها أي خيارات.

   


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