Releasing a drug selectively in specific locations in the body, including the brain, has been challenging. Researchers at the University of Utah have tackled the problem by designing ultrasound-sensitive nanoparticles that release a drug at the targeted site when activated by focused ultrasound.
A research team at the University of Washington and the Pacific Northwest National Laboratory examined the atomic composition of enamel samples from two human teeth.
Scientists have performed computer simulations confirming a technique that prevents the production of unhelpful electromagnetic waves, boosting the heat put into fusion plasma.
NIH awarded more than $4 million in funds and support services to three diagnostic technology developers as part of the RADx Tech’s Advanced Platforms for HIV Viral Load Monitoring program.
A first-of-its-kind study from researchers at the University of Minnesota Twin Cities shows how remote sensing can help monitor and remove plastic debris from freshwater environments like the Mississippi River.
Houston Methodist researchers have discovered that certain components of so-called “good” cholesterol -- high-density lipoproteins (HDL) – may be associated with an increased prevalence of cardiovascular disease.
A team of researchers at Roswell Park , led by Dhyan Chandra, PhD, has discovered a new therapeutic target for neuroendocrine prostate cancer, a rare and hard-to-treat form of prostate cancer. Their findings, newly published in the journal Oncogene, suggest that a set of processes known as the mitochondrial unfolded protein response, could be an Achilles’ heel for this often-deadly cancer type, and may point the way to a new treatment approach.
Enver Cagri Izgu, PhD, from the School of Arts and Sciences at Rutgers-New Brunswick, and his team will use a nearly $2 million NIH grant to develop diverse molecules with “programmed functionality” to address the fundamental challenges in therapeutic approaches that rely on modulating gene expression.
Study in mice reveals high-frequency mechanical vibrations detected by nerve endings on the skin are processed in a brain region deemed to be involved primarily in sound perception. Neurons in this brain region respond more strongly to sound and mechanical vibrations combined than to either one alone, resulting in an enhanced sensory experience.
To identify and follow blood vessel-related changes in the brain that contribute to cognitive impairment and dementia, researchers and clinicians typically rely on MRI to evaluate “downstream” biological markers – those at the end of a cascade of events. But a multicenter study led by UCLA researchers could lead to a cost-effective blood test to identify changes occurring near the top of the chain, potentially identifying at-risk patients at an earlier stage.
The National Institutes of Health have awarded a team of researchers at WashU Medicine a grant to investigate the underlying causes of cerebral small vessel disease, which is the second-leading cause of dementia.
The National Eye Institute (NEI)—which is the most important source of funding for all of vision research in the U.S.—is being threatened by a proposal from a committee in the House of Representatives to collapse the National Institutes of Health’s (NIH) 27 institutes into 15 institutes.
Washington University School of Medicine in St. Louis has received a renewal of a prestigious research grant from the National Cancer Institute. Led by principal investigator, Daniel Link, MD, the Specialized Program of Research Excellence (SPORE) grant in leukemia provides funding for translational research.
WashU scientists found that 57% of 201 samples of weedy rice collected from fields in nine counties or parishes of Missouri, Arkansas and Louisiana in 2022 were resistant to the imidazolinone (IMI) family of herbicides.
In a new study involving interviews of people with long COVID, researchers describe how the prolonged illness has affected not only patients’ job status, but also their overall well-being.
Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats. It turns out that two of these microbially-modified bile acids may affect our risk — in opposite directions — for developing colon cancer. Â
New research presented during the 2024 San Antonio Breast Cancer Symposium (SABCS) reveals a new machine learning model that could change the way metastatic breast cancer is treated in the future. By combining clinical and genomic data, physician-scientists from Memorial Sloan Kettering Cancer Center (MSK) developed a tool that could help improve predictions of how people with hormone receptor-positive, HER2-negative (HR+/HER2-) metastatic breast cancer respond to CDK4/6 inhibitors, a class of oral medications that control cell division and are often prescribed in combination with hormone therapy to treat this subset of patients.
An analysis of national data found that short-term mortality was not impacted for patients with advanced cancers during the shortage of the generic platinum chemotherapy drugs cisplatin and carboplatin that began in early 2023.
The federally funded pathway programs strive to increase diversity and equity in the cancer research field, a key strategy to reduce health disparities in the Chicagoland area and across the country.
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