Disruptions to Cholesterol in Cells Is an Early Sign of Beta Cell Damage in Model of Type 2 Diabetes
American Physiological Society (APS)
Until recently, it was believed that human urine is sterile, but advanced culturing techniques and DNA sequencing have revealed that bacteria and other microbes – such as viruses and fungi – inhabit the human bladder and urinary tract, known collectively as the “urobiome.” Now in study that is one of the first of its kind, Dr.
About 8 to 10 million Americans over age 40 have an overabundance of cloned white blood cells, or lymphocytes, that hamper their immune systems. Although many who have this condition — called monoclonal B-cell lymphocytosis (MBL) — do not experience any symptoms, a new study shows they may have an elevated risk for several health complications, including melanoma, a form of skin cancer.
With $10 million in funding from the National Institutes of Health, researchers from the University of Florida are storing post-surgical human tissue in a repository, collecting data points from the samples, and mapping and analyzing the tissue via artificial intelligence tools. The goal is to explore pain pathways and create custom pain treatments.
With newly awarded funding from the National Science Foundation, researchers at the University of California, Irvine and the Keck School of Medicine of USC will seek to revolutionize the treatment of neurological diseases through intelligent biocomputing. The four-year, $2 million grant is part of NSF’s Emerging Frontiers in Research and Innovation program, which funds cutting-edge science pushing the boundaries of human knowledge.
Tempo Therapeutics, Inc. ("Tempo"), a leader in tissue engineering and regenerative medicine, has announced the dosing of the first patients in the MOSAIC Trial, a clinical trial for TT101, the company’s lead candidate for tissue regeneration using its proprietary MAP technology.
The Bezos Centre for Sustainable Protein at the National University of Singapore (NUS) was launched today, marking a major milestone as the first of its kind in Asia to advance research in alternative proteins. With a US$30 million grant from the Bezos Earth Fund, the Centre is poised to lead groundbreaking research and commercialisation efforts to develop “ultimate proteins” – advanced hybrid foods that match traditional meat–based products in both taste and price.
Opeolu Adeoye, MD a professor of emergency medicine at Washington University School of Medicine in St. Louis, led a national clinical trial that found that two anti-coagulant medications are ineffective at improving post-treatment outcomes for stroke patients.
In humans and fruit flies alike, rna editing prevents autoimmune responses and adjusts protein functions. However, in humans, most editing occurs in non-coding regions, with only a small fraction leading to changes in protein function. In contrast, in flies, the majority of rna editing events occur in sequences that directly produce proteins.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
A multidisciplinary team of researchers from the National University of Singapore (NUS) has created a first-of-its-kind all-organic plant e-skin for continuous and non-invasive plant monitoring.
In a notable advancement, scientists have developed an efficient gene functional analysis method for peach seedlings, overcoming longstanding hurdles in genetic transformation. Utilizing a TRV-based vector system, this innovative approach induces high-frequency gene silencing across diverse plant tissues, enabling in-depth analysis of genes essential for growth and development. The streamlined process notably shortens the transformation and analysis timeline to just 1.5 months, accelerating advancements in horticultural research.
In the U.S. alone, more than 3.5 million babies are born each year. Alongside them, an endlessly fascinating organ that’s essential to a healthy pregnancy: the placenta.The placenta forms early in pregnancy, providing a vital connection between baby and mom. Then, it’s delivered shortly after the baby during childbirth, and its job is complete.
The National Science Foundation (NSF) has funded University of Illinois Urbana-Champaign research that aims to connect the dots between quantitative and molecular genetics and improve crop breeding.
Sustainable agriculture can benefit the environment but only when food safety and human health are taken into account.
The researchers used magneto-induced electric field (MIEF) technology to explore the structural and rheological properties of citrus pectin under different pH conditions. This technology is not only green and safe, but also easy to operate and low cost, suitable for industrial application.
Assistant Professor of Pharmaceutical Sciences Kuo-Ching (KC) Mei from Binghamton University, State University of New York and his team have won the $1.9M Maximizing Investigators’ Research Award (MIRA) for Early Stage Investigators (ESI) from the National Institute of General Medical Sciences to tackle gene therapy challenges.
New research from Memorial Sloan Kettering Cancer Center (MSK) uses cryo-electron microscopy to shed new light on the ubiquitin; could help predict the risk of blood clots in cancer patients; reveals why micronuclei burst, accelerating aggressive cancers; and surveys healthcare providers about the benefits and risks of commercial genetic testing.