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Curated News: NEJM

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Released: 29-Mar-2025 7:30 AM EDT
Rethinking Shadowing for Aspiring Physicians: New Study Calls for More Inclusive and Structured Clinical Experiences
Uniformed Services University of the Health Sciences (USU)

A new study from the Uniformed Services University (USU), "Rethinking Shadowing for Aspiring Physicians", published in the New England Journal of Medicine, challenges the traditional emphasis on physician shadowing as a key criterion for medical school admission, highlighting its financial and accessibility barriers for many aspiring doctors.

Not for public release

This news release is embargoed until 26-Mar-2025 7:45 PM EDT Released to reporters: 26-Mar-2025 7:45 PM EDT

A reporter's PressPass is required to access this story until the embargo expires on 26-Mar-2025 7:45 PM EDT The Newswise PressPass gives verified journalists access to embargoed stories. Please log in to complete a presspass application. If you have not yet registered, please Register. When you fill out the registration form, please identify yourself as a reporter in order to advance to the presspass application form.

Newswise: FDA Approves Dual-Action Drug for Patients with Previously Treated Advanced Neuroendocrine Tumors, Backed by Dana-Farber Research
Released: 26-Mar-2025 10:15 AM EDT
FDA Approves Dual-Action Drug for Patients with Previously Treated Advanced Neuroendocrine Tumors, Backed by Dana-Farber Research
Dana-Farber Cancer Institute

The FDA approval was based on results from the CABINET study, a phase 3 pivotal trial evaluating cabozantinib compared with placebo in two groups of patients with previously treated NETs: advanced pancreatic NETs and advanced extra-pancreatic NETs. The study was led by Jennifer Chan, MD, MPH, clinical director of the gastrointestinal cancer center and director of the program in carcinoid and neuroendocrine tumors at Dana-Farber Cancer Institute.

Released: 4-Mar-2025 7:05 PM EST
Pair of Studies Identify Promising New Treatments for Ulcerative Colitis
University of Chicago Medical Center

Two new drugs offer chance for patients who don’t respond to existing treatments to break through the “therapeutic ceiling” for ulcerative colitis.

Newswise: VUMC Part of New Study Validating Curative Therapy for Sickle Cell Disease
Released: 4-Mar-2025 10:50 AM EST
VUMC Part of New Study Validating Curative Therapy for Sickle Cell Disease
Vanderbilt University Medical Center

A modified bone marrow transplant procedure for sickle cell disease (SCD) co-developed at Vanderbilt University Medical Center, Johns Hopkins University School of Medicine, and the University of California, San Francisco, can cure the disease, a new study has found.

Newswise: Artificial Intelligence Helps Find Undiagnosed Liver Disease
Released: 27-Feb-2025 7:10 PM EST
Artificial Intelligence Helps Find Undiagnosed Liver Disease
Cedars-Sinai

An artificial intelligence (AI) program can identify chronic liver disease from videos taken during a common heart test known as an echocardiogram, Cedars-Sinai investigators report.

Released: 19-Feb-2025 8:20 PM EST
Text Message Tool Addresses “Time Toxicity” for Cancer Patients
Perelman School of Medicine at the University of Pennsylvania

A Penn Medicine pilot study shows it’s possible to use digital technology to safely reduce the amount of time some patients with cancer spend receiving care.

Released: 17-Feb-2025 8:25 PM EST
Researchers Look for the Best Ways to Help People with HIV Quit Smoking
University of Chicago Medical Center

Combining bupropion medication and a behavioral counseling program dramatically increased quit rates among people living with HIV who smoked.

Newswise: 1920_tricuspid-valve-smidt-heart-institute-cedars-sinai.jpg?10000
Released: 13-Feb-2025 8:20 PM EST
New Options for People With Tricuspid Valve Disease
Cedars-Sinai

People living with tricuspid valve disease are gaining more treatment options, driven by research from Cedars-Sinai investigators and collaborators at other leading medical institutions.

Released: 5-Feb-2025 5:00 PM EST
AI Tool Helps Find Life-Saving Medicine for Rare Disease
Perelman School of Medicine at the University of Pennsylvania

Set to enter hospice care, a patient with idiopathic multicentric Castleman’s disease is now in remission after treatment with a medication identified by an AI-guided analysis

Newswise: How Do You Treat Rotator-Cuff Tears?
Released: 3-Feb-2025 8:55 PM EST
How Do You Treat Rotator-Cuff Tears?
Michigan Medicine - University of Michigan

Shoulder symptoms led to an average of 9.6 million physician visits in 2015 and 2016 in the United States.The most common cause of those shoulder symptoms?Rotator-cuff disorders.Tears of the rotator cuff can result from a substantial traumatic injury or can occur slowly over time.

Released: 29-Jan-2025 5:00 PM EST
A Weekly Injection Could Replace Painful Daily Treatment for Rare Fat Disorder
Rutgers University-New Brunswick

A diabetes drug may beat costly shots for patients with a rare genetic condition, according to a Rutgers Health study.

Newswise: Study Finds Three New Safe, Effective Ways To Treat Drug-Resistant Tuberculosis
Released: 29-Jan-2025 5:00 PM EST
Study Finds Three New Safe, Effective Ways To Treat Drug-Resistant Tuberculosis
Harvard Medical School

• Study finds three new safe and effective drug regimens to fight multidrug-resistant TB • The treatments, which include recently discovered TB drugs, give new options for shorter, personalized treatment and are cleared for use for more people than ever

Released: 21-Jan-2025 7:45 PM EST
Clinical Trial to Study New Use for CAR T-cell Therapy: Treating Autoimmune Diseases
University of Chicago Medical Center

The University of Chicago Medicine has launched a Phase 2 clinical trial to study how CAR T-cell therapy could be used to treat three autoimmune diseases.

Released: 15-Jan-2025 9:55 AM EST
Study Published in NEJM Catalyst Finds Patients Cared for by MedStar Health's Safe Babies Safe Moms Program Have Better Outcomes in Pregnancy, Delivery, and Postpartum
MedStar Health

Women who were cared for by the MedStar Health D.C. Safe Babies Safe Moms program (SBSM) have better outcomes in pregnancy, delivery, and postpartum, according to a study published today in NEJM Catalyst Innovations in Care Delivery.

Newswise: Study Finds Transfusing More Blood Reduces Risk of Death at Six Months in Heart-Attack Patients With Anemia
Released: 23-Dec-2024 6:05 PM EST
Study Finds Transfusing More Blood Reduces Risk of Death at Six Months in Heart-Attack Patients With Anemia
Rutgers University-New Brunswick

A study led by Rutgers professor finds more liberal blood transfusions have more favorable results

Released: 10-Dec-2024 2:05 PM EST
Research Shows New Treatment Could Delay Cancer Progression in Patients with High-Risk Smoldering Multiple Myeloma
Mayo Clinic

A new treatment is showing promise for people with high-risk smoldering multiple myeloma (SMM). This precancerous condition can progress to active multiple myeloma, a type of blood cancer. High-risk SMM carries a higher likelihood of progression.

Newswise: New Research from Children’s Hospital of Philadelphia to Transform Standard of Care Across the Globe for Newly Diagnosed Children with B-cell Acute Lymphoblastic Leukemia
Released: 7-Dec-2024 10:00 AM EST
New Research from Children’s Hospital of Philadelphia to Transform Standard of Care Across the Globe for Newly Diagnosed Children with B-cell Acute Lymphoblastic Leukemia
Children's Hospital of Philadelphia

Researchers at Children’s Hospital of Philadelphia (CHOP) and the Children’s Oncology Group (COG) announced the results of a Phase 3 study that demonstrated adding the bi-specific T-cell engager, blinatumomab, to chemotherapy for newly diagnosed National Cancer Institute (NCI) standard risk (SR) B-cell acute lymphoblastic leukemia (B-ALL) pediatric patients significantly improves survival outcomes. The results were published today in the New England Journal of Medicine and will be presented during the plenary session at the 66th American Society of Hematology (ASH) Annual Meeting & Exposition in San Diego on December 8.

Released: 27-Nov-2024 5:05 PM EST
Novel CAR TCell Therapy Obe-Cel Demonstrates High Response Rates in Adult Patients with Advanced B-Cell ALL
University of Texas MD Anderson Cancer Center

Patients with relapsed or refractory CD19-positive B-cell acute lymphoblastic leukemia (ALL) who were treated with the novel anti-CD19 chimeric antigen receptor (CAR) T cell therapy, obecabtagene autoleucel (obe-cel), experienced high response rates and most did not need a subsequent stem cell transplant (SCT), according to results from the Phase Ib/II FELIX trial co-led by researchers at The University of Texas MD Anderson Cancer Center.



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