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Newswise — Acetyl-CoA is an important metabolite that affects the progression of many diseases. Researchers have now developed the first sensor for acetyl-CoA that works in living cells, letting scientists measure dynamic changes in the molecule at a subcellular level. “Being able to visualize this molecule will allow us and others to study its many important roles within cells, particularly in diseases like cancer and neurodegeneration,” says senior author Katharine Diehl, PhD.