High levels of physical activity may mitigate brain loss in adults and help maintain long-term cognitive health, researchers at UT Southwestern Medical Center report in a study published in the Journal of Applied Physiology.
The STING protein, known for helping cells fight viral infections by generating inflammation, also appears to function as a quality control sensor for organelles that serve as cellular waste disposal systems, UT Southwestern Medical Center researchers found.
More than one in four adults and one in five children in the U.S. have seasonal allergies (allergic rhinitis). And North Texas has a perfect climate for producing allergy-inducing pollen.
Much like human beings, songbirds learn how to vocalize from their parents. Males imitate songs from their fathers and then sing to attract mates.
The Cryo-Electron Microscopy Facility (CEMF) at UT Southwestern has vastly broadened the scope of molecules for which researchers are able to determine their 3D structures, accelerating the pace at which they can use this information to better understand diseases and develop new drugs to treat them.
Using a novel method that gives a readout of which proteins are in specific locations within cells, UT Southwestern Medical Center researchers have identified a protein that plays a key role in cell adhesion and movement. Their findings, published in Cell Reports, could help researchers better understand diverse phenomena such as cancer metastasis and cell differentiation.
A preclinical model developed at UT Southwestern Medical Center that recapitulates a rare infant-onset form of diabetes suggests the condition stems from gradual damage to the pancreas through misregulation of a molecular pathway called the unfolded protein response (UPR). The findings, published in Molecular Metabolism, could one day lead to new ways to treat more common subsets of diabetes, including Types 1 and 2, which affect hundreds of millions worldwide.
Measles is a highly contagious viral infection that can cause serious health problems. The good news: Two doses of the vaccine developed in the 1960s are 97% effective in protecting you from getting infected, and that protection lasts a lifetime.
One of the latest neuromodulation therapies available at UTSWās Peter OāDonnell Jr. Brain Institute is transcranial magnetic stimulation (TMS). This therapy uses external magnets and coils to depolarize affected neurons, āresettingā the connected networks to restore normal function.
A multidisciplinary team of UT Southwestern Medical Center specialists, led by Nader Pouratian, M.D., Ph.D., and Peter Tsai, M.D., Ph.D., has received a grant worth up to $5 million from the Raynor Cerebellum Project to develop neuromodulation therapies for patients with cerebellar disorders of the brain.
Malaria, responsible for hundreds of thousands of deaths each year worldwide, is caused by a parasite transmitted through the salivary glands of female Anopheles mosquitoes. Understanding the biology of these tissues is critical to developing new treatments for the disease, found mostly in tropical countries.
An emotional overattachment to social media may be associated with increased severity of mental health symptoms among young people being treated for depression, anxiety, and suicidal thoughts, according to researchers at UT Southwestern Medical Center.
Cheers abounded as 222 UT Southwestern students, surrounded by friends and family, proudly showed off their matches with more than 80 residency programs across the U.S. After graduating in May, they will be heading to prestigious hospitals across the country, including Massachusetts General, Johns Hopkins, UCSF, and Northwestern.
While cigarette smoking rates have plummeted from nearly 50% of adults in the 1960s to just under 12% in 2022, people use other tobacco products at about the same rate as they always have.
A protein called angiopoietin-2 (ANGPT2) can both inhibit and encourage blood vessel changes critical for sepsis, a leading cause of hospital deaths worldwide, a new study led by UT Southwestern Medical Center researchers shows.
A clot-busting drug recently approved to treat acute ischemic strokes (AIS) that can be delivered quickly works as well as a decades-old medication used by most hospitals in the U.S. and could hold significant advantages for some patients, a study led by a UT Southwestern Medical Center researcher shows. The findings, published in JAMA Network Open, could encourage more hospitals to use the newer drug, tenecteplase.
A new āself-drivingā microscope developed by UT Southwestern Medical Center researchers solves two fundamental challenges that have long plagued microscopy: first, imaging living cells or organisms at dramatically different scales, and second, following a specific structure or area of interest over long periods of time.
High-protein diets and protein-enriched foods seem to be everywhere we turn. Itās a nutrition trend with a refreshingly positive vibe. Unlike carbohydrates and fats, protein is the only one of the three macronutrients that doesnāt get vilified ā instead of cutting back, weāre encouraged to boost our intake!
While randomized comparative trials are needed, a relatively new treatment option for upper urinary tract cancers shows promise for lowering long-term recurrence in many patients with low-grade disease, according to a multicenter study led by researchers at UT Southwestern Medical Center.
Repeated sessions of electrical stimulation to brain networks associated with memory improved verbal learning in some Alzheimerās disease patients for up to eight weeks in a preliminary trial led by UT Southwestern Medical Center researchers.
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