Latest news from UT Southwestern Medical Center on Newswise en-us Copyright 2025 Newswise 115 31 / /images/newswise-logo-rss.gif /articles/preoperative-immunotherapy-could-enhance-breast-cancer-cure-rates/?sc=rsin /articles/preoperative-immunotherapy-could-enhance-breast-cancer-cure-rates/?sc=rsin Tue, 04 Feb 2025 20:20:56 EST A phase three clinical trial co-led by a researcher at UT Southwestern Harold C. Simmons Comprehensive Cancer Center showcases the promise of administering immunotherapy along with chemotherapy before surgery in patients with breast cancer at high risk of spreading. UT Southwestern Medical Center /articles/study-reveals-cellular-recycling-process-key-to-human-health/?sc=rsin /articles/study-reveals-cellular-recycling-process-key-to-human-health/?sc=rsin Mon, 03 Feb 2025 18:45:14 EST A team led by UT Southwestern Medical Center researchers has identified a key mechanism responsible for endosomal recycling in cells, a process critical to human health. Their findings, published in Nature Communications, answer a fundamental question in cell biology and could lead to therapies for conditions including neurological disorders and cancer. UT Southwestern Medical Center /articles/how-a-north-texas-woman-survived-rare-genetic-lung-cancer-and-saved-her-mom/?sc=rsin /articles/how-a-north-texas-woman-survived-rare-genetic-lung-cancer-and-saved-her-mom/?sc=rsin Fri, 31 Jan 2025 19:15:17 EST Most families discover inherited genetic mutations after one member develops a health problem unusual to their age. This can prompt younger generations to get genetic testing. But in the case of Cassie Munoz and her family, the scenario was reversed. UT Southwestern Medical Center /articles/how-cervical-cancer-screening-with-hpv-testing-is-saving-lives/?sc=rsin /articles/how-cervical-cancer-screening-with-hpv-testing-is-saving-lives/?sc=rsin Fri, 31 Jan 2025 18:30:56 EST January is Cervical Cancer Awareness Month, so it's the perfect time to review facts about cervical cancer, HPV-associated risks, and screening recommendations. We'll also look at self-collected tests that have recently sparked interest. UT Southwestern Medical Center /articles/shorter-safer-protocol-effectively-treats-triple-negative-breast-cancer/?sc=rsin /articles/shorter-safer-protocol-effectively-treats-triple-negative-breast-cancer/?sc=rsin Thu, 30 Jan 2025 19:40:56 EST A far shorter, simpler, and less toxic treatment protocol for patients with triple-negative breast cancer produced outcomes similar to the current standard of care, a clinical trial co-led by a UT Southwestern Medical Center researcher shows. The findings, published in the Journal of Clinical Oncology, could lead to new treatment regimens that are significantly safer and less detrimental to patients' quality of life. UT Southwestern Medical Center /articles/be-mindful-of-what-you-eat-and-drink-at-super-bowl-parties/?sc=rsin /articles/be-mindful-of-what-you-eat-and-drink-at-super-bowl-parties/?sc=rsin Wed, 29 Jan 2025 16:05:40 EST If you're planning to join family and friends to watch Super Bowl LIX, you know there will be snacks and drinks galore to tantalize you for four quarters. But to ensure you don't go overboard with the party smorgasbord, it's best to practice mindfulness as a key strategy, advises a lifestyle medicine expert at UT Southwestern Medical Center. UT Southwestern Medical Center /articles/utsw-joins-effort-to-create-early-screening-for-dementia/?sc=rsin /articles/utsw-joins-effort-to-create-early-screening-for-dementia/?sc=rsin Tue, 28 Jan 2025 18:45:48 EST UT Southwestern Medical Center is among 10 U.S. health systems selected for an initiative that aims to create and implement early detection programs for Alzheimer's disease and other cognitive impairments. UT Southwestern Medical Center /articles/study-reveals-biomarker-for-high-risk-of-metastasis/?sc=rsin /articles/study-reveals-biomarker-for-high-risk-of-metastasis/?sc=rsin Mon, 27 Jan 2025 19:15:22 EST A team led by UT Southwestern scientists has discovered a mechanism that promotes metastasis in pancreatic, breast, and potentially other cancers along with a new druggable therapeutic target to block it. The findings, published in Science Signaling, represent an important lead in developing new drugs to prevent tumors from spreading, the cause of death among most patients with cancer. UT Southwestern Medical Center /articles/mood-disorders-drive-feelings-of-cognitive-decline-in-former-college-athletes/?sc=rsin /articles/mood-disorders-drive-feelings-of-cognitive-decline-in-former-college-athletes/?sc=rsin Thu, 23 Jan 2025 18:20:50 EST Former college athletes with a history of concussions were more likely to perceive themselves as cognitively impaired later in life if they had mood disorders such as depression and anxiety - even when testing showed no such decline in mental acuity, a study by UT Southwestern Medical Center researchers has found. UT Southwestern Medical Center /articles/utsw-research-covid-19-s-effects-brain-computer-interfaces-and-more/?sc=rsin /articles/utsw-research-covid-19-s-effects-brain-computer-interfaces-and-more/?sc=rsin Wed, 22 Jan 2025 18:45:42 EST Briefs package: Assessing multiple sclerosis symptoms after COVID-19; Building better brain-computer interfaces; Shedding light on structure of certain receptors in brain; RNA-modifying protein mutations linked to cancer UT Southwestern Medical Center /articles/experimental-depression-treatment-preserves-cognitive-function/?sc=rsin /articles/experimental-depression-treatment-preserves-cognitive-function/?sc=rsin Tue, 21 Jan 2025 17:10:03 EST An experimental treatment for depression that triggers seizures with magnets significantly improved mental health in patients without some cognitive effects associated with electroconvulsive therapy (ECT), a clinical trial led by UT Southwestern Medical Center researchers showed. UT Southwestern Medical Center /articles/study-implicates-another-gene-in-brain-that-causes-weight-gain/?sc=rsin /articles/study-implicates-another-gene-in-brain-that-causes-weight-gain/?sc=rsin Wed, 15 Jan 2025 21:00:00 EST Mutations in a gene called OTP cause obesity by controlling the output of another gene already targeted by an anti-obesity drug, a study led by UT Southwestern Medical Center researchers shows. The findings, reported in Science Translational Medicine, could lead to new treatments for some types of obesity, a growing health problem that currently affects more than a billion people worldwide. UT Southwestern Medical Center /articles/ut-southwestern-pharmacologists-earn-hill-prize-from-tamest/?sc=rsin /articles/ut-southwestern-pharmacologists-earn-hill-prize-from-tamest/?sc=rsin Wed, 15 Jan 2025 17:30:36 EST David Mangelsdorf, Ph.D., Chair and Professor of Pharmacology and Professor of Biochemistry at UT Southwestern Medical Center, has been awarded the Hill Prize in Biological Sciences from the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST) in recognition of his long-standing research on orphan nuclear receptors - proteins in the cell nucleus that flip genes on and off and are triggered by unknown molecules. UT Southwestern Medical Center /articles/autoimmune-skin-condition-linked-to-higher-risk-of-heart-disease/?sc=rsin /articles/autoimmune-skin-condition-linked-to-higher-risk-of-heart-disease/?sc=rsin Mon, 13 Jan 2025 20:50:09 EST Patients with cutaneous lupus erythematosus (CLE), an autoimmune disease that causes skin inflammation, have a higher risk for atherosclerotic cardiovascular disease (ASCVD), or hardening of the arteries, UT Southwestern Medical Center researchers found. Their study, published in JAMA Dermatology, suggests CLE patients should be screened early for heart disease. UT Southwestern Medical Center /articles/how-spinal-fusion-saved-a-2-year-old-after-a-devastating-car-accident/?sc=rsin /articles/how-spinal-fusion-saved-a-2-year-old-after-a-devastating-car-accident/?sc=rsin Mon, 13 Jan 2025 18:40:30 EST When 2-year-old Owen Page was ejected from the car he was riding in during a crash, his skull internally separated from his spine, an injury known as atlanto-occipital dislocation (AOD). UT Southwestern Medical Center /articles/end-of-life-care-more-aggressive-for-cancer-patients-with-defibrillators/?sc=rsin /articles/end-of-life-care-more-aggressive-for-cancer-patients-with-defibrillators/?sc=rsin Wed, 08 Jan 2025 19:15:07 EST Patients with advanced cancer who also had cardiac defibrillators were more likely than those without these implants to receive aggressive end-of-life care, a team led by UT Southwestern Medical Center researchers found in a new study. The findings, published in Cancer, could help physicians guide patients in this growing population toward care that better matches their goals. UT Southwestern Medical Center /articles/how-sex-and-age-shape-fat-patterns-in-muscles-and-bones/?sc=rsin /articles/how-sex-and-age-shape-fat-patterns-in-muscles-and-bones/?sc=rsin Tue, 07 Jan 2025 18:55:18 EST Researchers at UT Southwestern Medical Center have discovered sex-specific differences in how fat accumulates in muscle and bone, uncovering patterns that could inform new approaches to treating age-related diseases. UT Southwestern Medical Center /articles/stimulating-fat-cells-with-gip-receptor-has-potential-to-treat-obesity/?sc=rsin /articles/stimulating-fat-cells-with-gip-receptor-has-potential-to-treat-obesity/?sc=rsin Mon, 06 Jan 2025 16:05:54 EST Obese mice whose fat cells were genetically altered to produce an increased amount of the glucose-dependent insulinotropic polypeptide receptor (GIPR) lost more than a third of their body weight through a mechanism that burns energy, UT Southwestern Medical Center researchers report in a new study. Published in Cell Metabolism, the findings highlight the potential of GIPR - a protein thought of as a minor player in a class of popular weight-loss drugs - to have its own starring role in therapies to fight obesity. UT Southwestern Medical Center /articles/good-cholesterol-may-protect-against-brain-atrophy-dementia/?sc=rsin /articles/good-cholesterol-may-protect-against-brain-atrophy-dementia/?sc=rsin Thu, 02 Jan 2025 17:45:40 EST High-density lipoprotein (HDL), or "good" cholesterol, may play a vital role in conserving healthy brain matter in middle-aged adults, UT Southwestern Medical Center researchers report. The findings, published in the Journal of Clinical Medicine, could give doctors and patients more insight into factors that affect cognitive health in aging adults. UT Southwestern Medical Center /articles/cri-scientists-link-hematopoietic-cell-transplant-deaths-to-beta-blocker-use/?sc=rsin /articles/cri-scientists-link-hematopoietic-cell-transplant-deaths-to-beta-blocker-use/?sc=rsin Mon, 30 Dec 2024 15:55:13 EST Patients can die if they take certain previously prescribed beta-blockers during a hematopoietic cell transplant due to suppressed signals from nerves that promote bone marrow regeneration. UT Southwestern Medical Center