Latest News from: St. Jude Children's Research Hospital

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Newswise: Early interventions may improve long-term academic achievement in young childhood brain tumor survivors
Released: 21-Aug-2024 12:05 PM EDT
Early interventions may improve long-term academic achievement in young childhood brain tumor survivors
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital found infants and young children treated for brain tumors fell behind early in academic readiness, which predicted falling behind in later school years.

Newswise: T helper cells may be the key to improving annual influenza vaccines
Released: 20-Aug-2024 10:05 AM EDT
T helper cells may be the key to improving annual influenza vaccines
St. Jude Children's Research Hospital

The annual influenza vaccination provides updated protection against the virus but could be improved as there is large variability in its efficacy.

Newswise: Study reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease
Released: 12-Aug-2024 1:30 PM EDT
Study reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease
St. Jude Children's Research Hospital

Respiratory infections can be severe, even deadly, in some individuals, but not in others. Scientists at St. Jude Children’s Research Hospital, the Peter Doherty Institute for Infection and Immunity and other collaborators have gained new understanding of why this is the case by uncovering an early molecular driver that underpins fatal disease.

Newswise: Scientists identify genes linked to relapse in the most common form of childhood leukemia
Released: 12-Aug-2024 11:50 AM EDT
Scientists identify genes linked to relapse in the most common form of childhood leukemia
St. Jude Children's Research Hospital

Scientists from St. Jude Children’s Research Hospital, Seattle Children’s and the Children’s Oncology Group (COG) have identified novel genetic variations that influence relapse risk in children with standard risk B-cell acute lymphoblastic leukemia (SR B-ALL), the most common childhood cancer.

Newswise: St. Jude identifies SARS-CoV-2 “mimic” contributing to pediatric inflammatory syndrome
Released: 7-Aug-2024 1:05 PM EDT
St. Jude identifies SARS-CoV-2 “mimic” contributing to pediatric inflammatory syndrome
St. Jude Children's Research Hospital

Discover St. Jude research from Paul Thomas, PhD, linking SARS-CoV-2 infections and molecular mimicry with multisystem inflammatory syndrome in children.

Newswise: Genetic ‘episignatures’ guide researchers in identifying causes of unsolved epileptic neurological disorders
Released: 6-Aug-2024 3:05 PM EDT
Genetic ‘episignatures’ guide researchers in identifying causes of unsolved epileptic neurological disorders
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital use DNA methylation patterns as a roadmap for identifying causes of severe epilepsies in children.

Newswise: Age impacts pharmacogenomics and treatment outcomes for most common form of leukemia
Released: 5-Aug-2024 5:05 PM EDT
Age impacts pharmacogenomics and treatment outcomes for most common form of leukemia
St. Jude Children's Research Hospital

Explore how scientists at St. Jude Children’s Research Hospital have identified causes for age-related differences in treatment outcomes of B-cell acute lymphoblastic leukemia.

Newswise: Improved chemokine homing enhances CAR T–cell therapy for osteosarcoma
Released: 5-Aug-2024 12:05 PM EDT
Improved chemokine homing enhances CAR T–cell therapy for osteosarcoma
St. Jude Children's Research Hospital

Learn how scientists at St. Jude are leading research to improve CAR T-cell therapy for osteosarcoma by enhancing chemokine homing.

Newswise: Serotonin uptake regulates ependymoma tumor growth
Released: 31-Jul-2024 2:05 PM EDT
Serotonin uptake regulates ependymoma tumor growth
St. Jude Children's Research Hospital

St. Jude Children’s Research Hospital and Baylor College of Medicine have implicated the neurotransmitter serotonin in ependymoma tumor growth, suggesting a new class of drugs to test against these tumors.

Newswise: Biomolecular condensate ‘molecular putty’ properties found encoded in protein sequence
Released: 2-Jul-2024 12:05 PM EDT
Biomolecular condensate ‘molecular putty’ properties found encoded in protein sequence
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital, the State University of New York at Buffalo and Washington University at St. Louis probed how condensates behave like viscoelastic putty and age to more solid states.

Newswise: Master autoimmune regulator gets by with a little help from its friends
Released: 27-Jun-2024 1:05 PM EDT
Master autoimmune regulator gets by with a little help from its friends
St. Jude Children's Research Hospital

See how St. Jude researchers investigated Foxp3 function as a transcription cofactor in regulatory T cells in immune system activation and suppression.

Newswise: Children genetically prone to cancer benefit from early standardized surveillance
Released: 20-Jun-2024 12:05 PM EDT
Children genetically prone to cancer benefit from early standardized surveillance
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital found that, with early screening, they could detect new cancers in pediatric patients with an underlying genetic predisposition at their most treatable stages.

Newswise: St. Jude scientists solve decades long mystery of NLRC5 sensor function in cell death
Released: 14-Jun-2024 3:40 PM EDT
St. Jude scientists solve decades long mystery of NLRC5 sensor function in cell death
St. Jude Children's Research Hospital

Learn about immunology research from the St. Jude laboratory of Thirumala-Devi Kanneganti, PhD, that revealed the function of the NLRC5 innate immune sensor. 

   
Newswise: Novel insights into fluorescent ‘dark states’ illuminate ways forward for improved imaging
Released: 14-Jun-2024 12:05 PM EDT
Novel insights into fluorescent ‘dark states’ illuminate ways forward for improved imaging
St. Jude Children's Research Hospital

St. Jude Children’s Research Hospital scientists address decades-long problem in the field of single-molecule fluorescence resonance energy transfer, paving the way for more accurate experiments.

Newswise: Age is just a number: Immune cell ‘epigenetic clock’ ticks independently of organism lifespan 
Released: 12-Jun-2024 10:50 AM EDT
Age is just a number: Immune cell ‘epigenetic clock’ ticks independently of organism lifespan 
St. Jude Children's Research Hospital

See how St. Jude researchers use epigenetic clock, DNA methylation and mouse model to demonstrate that T cell proliferation can stretch past organism lifespan and acuta lymphoblastic leukemia T cells appear hundreds of years old.

Newswise: Cell-targeting technology allows researchers to isolate neuronal subpopulations and link them to behavioral states
Released: 28-May-2024 12:05 PM EDT
Cell-targeting technology allows researchers to isolate neuronal subpopulations and link them to behavioral states
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital designed an intersectional technique for precisely targeting subpopulations of cells and parsing out specific functions.

   
Newswise: Repurposed protease controls important signaling molecule-activating protein
Released: 22-May-2024 11:05 AM EDT
Repurposed protease controls important signaling molecule-activating protein
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital reveal the role of iRhom2’s defunct protein-cleaving domain in lifecycle of ADAM17, a key signaling molecule-activating protein.

Newswise: Novel inhibitor insights offer pathway to preventing PXR-associated drug resistance
Released: 14-May-2024 4:05 PM EDT
Novel inhibitor insights offer pathway to preventing PXR-associated drug resistance
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital uncovered a route to blocking activity of protein notorious for eliminating drugs, offering a potential boon to cancer therapy.

Newswise: Hongbo Chi, PhD named 2023 AAAS Fellow
Released: 29-Apr-2024 1:05 PM EDT
Hongbo Chi, PhD named 2023 AAAS Fellow
St. Jude Children's Research Hospital

Hongbo Chi, PhD, a faculty member and the Robert G. Webster Endowed Chair in Immunology at St. Jude Children’s Research Hospital, has been recognized as a fellow of the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society and publisher of the Science Family of Journals.

Newswise: Targeting specific protein regions offers a new treatment approach in medulloblastoma
Released: 25-Apr-2024 2:05 PM EDT
Targeting specific protein regions offers a new treatment approach in medulloblastoma
St. Jude Children's Research Hospital

Explore how research targeting EP300/CBP protein in Group 3 medulloblastoma may advance targeted pediatric brain tumor treatments by inhibiting bromodomains.



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