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Released: 9-Apr-2025 6:30 PM EDT
Hidden Forces Shape Plants From the Inside Out
Universite de Montreal

UdeM scientists use a combination of experimental data and modelling to reveal how physical forces help plants to generate their complex 3D shapes.

Released: 8-Apr-2025 7:05 AM EDT
Ventris Medical Receives Additional FDA Clearance for BackpackĀ® Bone Graft in the Intervertebral Disc Space
Ventris Medical

Ventris Medical, a privately held orthobiologics and tissue regeneration company, today announced that the United States Food and Drug Administration has granted 510(k) clearance for BackpackĀ® (Porous Biologic Scaffold, K250556) for use in the Intervertebral Disc Space.

   
Newswise:Video Embedded curious-by-nature-dr-gilbert-bernier-can-stem-cells-cure-blindness
VIDEO
Released: 4-Apr-2025 5:50 PM EDT
Curious by Nature: Dr. Gilbert Bernier - Can Stem Cells Cure Blindness?
Newswise

Dr. Gilbert Bernier, a neuroscientist and professor at the University of Montreal who is pushing the boundaries of regenerative medicine.

Released: 4-Apr-2025 5:00 AM EDT
NK Cells Complexed with Bispecific Antibody Yield High Response Rates in Patients with Lymphoma
University of Texas MD Anderson Cancer Center

A novel cell therapy approach using cord blood-derived natural killer (NK) cells pre-complexed with AFM13, or acimtamig, a CD30/CD16A bispecific antibody, was safe and generated strong response rates for patients with refractory CD30-positive lymphomas, according to a new study from The University of Texas MD Anderson Cancer Center.

Newswise: New Method Creates 854x More Mitochondria, Offering Hope for Cartilage Regeneration
Released: 31-Mar-2025 6:10 AM EDT
New Method Creates 854x More Mitochondria, Offering Hope for Cartilage Regeneration
Chinese Academy of Sciences

Scientists have unveiled a revolutionary method for mass-producing high-quality human mitochondria, potentially transforming treatments for degenerative diseases. By refining stem cell culture conditions, researchers achieved an extraordinary 854-fold increase in mitochondrial production while significantly enhancing energy output.

Released: 26-Mar-2025 12:00 PM EDT
Regulation of lncRNA-ENST on Myc-Mediated Mitochondrial Apoptosis in Mesenchymal Stem Cells: In Vitro Evidence Implicated for Acute Lung Injury Therapeutic Potential
World Journal of Stem Cells

BACKGROUNDAcute lung injury (ALI) is a fatal and heterogeneous disease. While bone marrow mesenchymal stem cells (BMSCs) have shown promise in ALI repair, their efficacy is compromised by a high apoptotic percentage. Preliminary findings ha

Released: 26-Mar-2025 12:00 PM EDT
Emerging Role of Mesenchymal Stem Cell-Derived Exosomes in the Repair of Acute Kidney Injury
World Journal of Stem Cells

Acute kidney injury (AKI) is a clinical syndrome characterized by a rapid deterioration in kidney function and has a significant impact on patient health and survival. Mesenchymal stem cells (MSCs) have the potential to enhance renal functi

Released: 26-Mar-2025 12:00 PM EDT
Immunomodulatory Effects and Clinical Application of Exosomes Derived From Mesenchymal Stem Cells
World Journal of Stem Cells

Exosomes (Exos) are extracellular vesicles secreted by cells and serve as crucial mediators of intercellular communication. They play a pivotal role in the pathogenesis and progression of various diseases and offer promising avenues for the

Released: 26-Mar-2025 12:00 PM EDT
Cyclodextrin Host-Guest Complex to Facilitate Sinomenine-Based Osteoporosis Therapy
World Journal of Stem Cells

Xiao et al reported on the natural product sinomenine (SIN), which is a traditional Chinese medicine for treating osteoporosis via its modulation of autophagy; however, SIN was dissolved in dimethyl sulfoxide prior to administration, which

Released: 26-Mar-2025 12:00 PM EDT
DNA Methyltransferase 1/miR-342-3p/Forkhead box M1 Signaling Axis Promotes Self-Renewal in Cervical Cancer Stem-Like Cells in Vitro and Nude Mice Models
World Journal of Stem Cells

BACKGROUNDCervical cancer (CC) stem cell-like cells (CCSLCs), defined by the capacity of differentiation and self-renewal and proliferation, play a significant role in the progression of CC. However, the molecular mechanisms regulating thei

Released: 26-Mar-2025 12:00 PM EDT
MiR-21-5p-enriched exosomes from hiPSC-derived cardiomyocytes exhibit superior cardiac repair efficacy compared to hiPSC-derived exosomes in a murine MI model
World Journal of Stem Cells

BACKGROUNDHeart disease remains a leading cause of mortality worldwide, with existing treatments often failing to effectively restore damaged myocardium. Human-induced pluripotent stem cells (hiPSCs) and their derivatives offer promising th

Released: 26-Mar-2025 12:00 PM EDT
Efficacy Equivalence but Hidden Hurdles: Can Serum-Free Human Umbilical Cord Mesenchymal Stem Cells Translate to Clinically Superior Osteoarthritis Therapy
World Journal of Stem Cells

This article discusses the study by Xiao et al, which investigated the therapeutic efficacy of serum-free cultured human umbilical cord mesenchymal stem cells (N-hUCMSCs) in a mouse model of knee osteoarthritis. The results showed that N-hU

Released: 26-Mar-2025 12:00 PM EDT
Clinical Experience with Cryopreserved Mesenchymal Stem Cells for Cardiovascular Applications: A Systematic Review
World Journal of Stem Cells

BACKGROUNDAs living biodrugs, mesenchymal stem cells (MSCs) have progressed to phase 3 clinical trials for cardiovascular applications. However, their limited immediate availability hampers their routine clinical use. AIMTo validate our hy

Released: 26-Mar-2025 12:00 PM EDT
Mesenchymal Stem Cell Exosomes Enhance the Development of Hair Follicle to Ameliorate Androgenetic Alopecia
World Journal of Stem Cells

BACKGROUNDMesenchymal stem cells (MSCs) and their secretome have significant potential in promoting hair follicle development. However, the effects of MSC therapy have been reported to vary due to their heterogeneous characteristics. Differ

Newswise: Stem Cell Trial for Early Alzheimerā€™s Disease Begins at UTHealth Houston
Released: 14-Mar-2025 10:15 AM EDT
Stem Cell Trial for Early Alzheimerā€™s Disease Begins at UTHealth Houston
University of Texas Health Science Center at Houston

A stem cell therapy trial aimed at reducing neuroinflammation in patients with presymptomatic Alzheimerā€™s disease is underway at UTHealth Houston.

Newswise: Childrenā€™s Hospital of Philadelphia Preclinical Study Demonstrates Improved Gene Therapy Approach to Treating Metachromatic Leukodystrophy
Released: 11-Mar-2025 7:20 PM EDT
Childrenā€™s Hospital of Philadelphia Preclinical Study Demonstrates Improved Gene Therapy Approach to Treating Metachromatic Leukodystrophy
Children's Hospital of Philadelphia

In a preclinical study, researchers at Childrenā€™s Hospital of Philadelphia (CHOP) demonstrated a novel gene therapy with potentially increased effectiveness and safety for the treatment for metachromatic leukodystrophy (MLD), a rare disease in young children characterized by the deficient activity of a critical enzyme.

Newswise: VUMC Part of New Study Validating Curative Therapy for Sickle Cell Disease
Released: 4-Mar-2025 10:50 AM EST
VUMC Part of New Study Validating Curative Therapy for Sickle Cell Disease
Vanderbilt University Medical Center

A modified bone marrow transplant procedure for sickle cell disease (SCD) co-developed at Vanderbilt University Medical Center, Johns Hopkins University School of Medicine, and the University of California, San Francisco, can cure the disease, a new study has found.

Newswise: 1920_cedars-sinai-heart-cells-proteomics.jpg?10000
Released: 4-Mar-2025 4:00 AM EST
Research Tip Sheet: New Single-Cell Proteomics Technology Reveals Heart Cell Differences
Cedars-Sinai

A multidisciplinary team of Cedars-Sinai investigators has used a novel single-cell proteomics approach to better understand the differences between naturally occurring adult heart cells and heart cells derived from induced pluripotent stem cells.

Newswise: Treatment Strategy Reprograms Brain Cancer Cells, Halting Tumor Growth
Released: 26-Feb-2025 5:25 PM EST
Treatment Strategy Reprograms Brain Cancer Cells, Halting Tumor Growth
University of California, Los Angeles (UCLA), Health Sciences

UCLA scientists have identified a potential new strategy for treating glioblastoma, the deadliest form of brain cancer, by reprogramming aggressive cancer cells into harmless ones.

Released: 26-Feb-2025 12:00 PM EST
Asthma and Stem Cell Therapy
World Journal of Stem Cells

The global incidence of asthma, a leading respiratory disorder affecting more than 235 million people, has dramatically increased in recent years. Characterized by chronic airway inflammation and an imbalanced response to airborne irritants



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