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The increase of microbes resistant to antibiotics is a growing problem. These include, for example, Neisseria gonorrhoeae, a bacterium which causes gonorrhea. Researchers from the universities in Konstanz and Vienna discover a new class of antibiotic that selectively targets Neisseria gonorrhoeae. These substances trigger a self-destruction program, which also operates in multi-resistant variants of the pathogen. This type of treatment could be used in an adapted form against other pathogens, so the scientists have made a real breakthrough in the fight against superbugs. The results have been published in the renowned journal Nature Microbiology.

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Georgia Tech scientists are revealing how decades-long research programs have transformed our understanding of evolution, from laboratory petri dishes to tropical islands 鈥� along the way uncovering secrets that would remain hidden in shorter studies.

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Scientists have unveiled a revolutionary method for mass-producing high-quality human mitochondria, potentially transforming treatments for degenerative diseases. By refining stem cell culture conditions, researchers achieved an extraordinary 854-fold increase in mitochondrial production while significantly enhancing energy output.

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A newly developed blood test for Alzheimer鈥檚 disease not only aids in the diagnosis of the neurodegenerative condition but also indicates how far it has progressed, according to a study by researchers at Washington University School of Medicine in St. Louis and Lund University in Sweden.

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Promethium鈥檚 short half-life and lack of stable isotopes makes it difficult to study. In addition, promethium is difficult to separate from other lanthanide elements because of these elements鈥� similarity. In this study, scientists created a pure sample of the isotope promethium-147 and used X-ray absorption spectroscopy to examine the way it chemically bonds.

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A study led by Johns Hopkins Medicine researchers could advance the development of new drugs that block or open such signaling channels to treat conditions as varied as epilepsy and some intellectual disorders.

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The team led by Associate Professor Mario Lanza from the Department of Materials Science and Engineering in the College of Design and Engineering at the National University of Singapore, has just revolutionised the field of neuromorphic computing by inventing a new super-efficient computing cell that can mimic the behaviour of both electronic neurons and synapses.

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To make inorganic materials such as catalysts, industry mixes precursor powders and fires them in an oven. This often produces a mix of compositions and structures. In this study, researchers developed a new way to select precursors to increase yield and quickly validated their results using a robotic lab. The new recipe selection process obtained higher purity for 32 of the 35 target materials.

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UChicago researchers develop a new technology to create a spatial map of gene expression for an entire organism.

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Professor Ariando and Dr Stephen Lin Er Chow from the National University of Singapore (NUS) Department of Physics have designed and synthesised a groundbreaking new material鈥攁 copper-free superconducting oxide鈥攃apable of superconducting at approximately 40 Kelvin (K), or about minus 233 degrees Celsius (deg C), under ambient pressure.

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Around 98 per cent of lignin created as a forestry by-product from plants is discarded, but a new enzyme could be the key to extracting high-value molecules from this waste using a green chemistry approach.

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Georgia Tech scientists uncovered how whole-genome duplication emerges and remains stable over thousands of generations of evolution in the lab.

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MSU engineers create 鈥渟mart鈥� system to prevent future infrastructure disasters

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A McMaster University team led by renowned researcher Gerry Wright has identified a strong candidate to challenge even some of the most drug-resistant bacteria on the planet: a new molecule called lariocidin.

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"Our ultimate goal is to develop vaccines against these very difficult viruses. Understanding how these viruses manipulate the immune response can help guide the development of the best vaccine approach."

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A breakthrough in safely delivering therapeutic DNA to cells could transform treatment for millions suffering from common chronic diseases like heart disease, diabetes, and cancer.

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Higher dimension 鈥榪udits鈥� may offer advantages over qubits in quantum computing, according to new research published in Nature Physics.

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For human health, prematurely aging cells are a big problem. When a cell ages and stops growing, its function changes, which can cause or worsen cardiovascular disease, Alzheimer鈥檚 disease and other chronic diseases. But these cells are also like needles in a haystack, difficult to identify by traditional scientific measures.

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Cedars-Sinai investigators have developed a novel artificial intelligence (AI) model, named DYNA, that accurately distinguishes harmful gene variations from harmless ones, potentially enhancing physicians鈥� ability to diagnose diseases. The new tool could pave the way for more precise personalized medicine and targeted therapies.