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Researchers have identified the job of one of the most common DNA-damage response proteins, an enzyme that has puzzled scientists every since it was discovered. DinB DNA polymerase turns out to be a specialist at accurate replication of a particular kind of damaged DNA.
In a study of the travels of the malaria parasite Plasmodium through mammalian tissue, researchers found the parasites developing in an unexpected place: the lymph nodes. The findings could help scientists develop more effective vaccines.
An HHMI-supported undergraduate's research reveals the neurological mechanism used to enter torpor, a hibernation-like state. The finding could help doctors treat stroke patients more effectively.
Scientists in India, led by a Howard Hughes Medical Institute international research scholar, have identified five key genes that enable the bacterium that causes TB to acquire the iron it needs to sustain growth and promote infection.
An innovative way of categorizing myosin, one of three molecular motors that produce movement within cells, has dramatically increased the amount of information available about these essential proteins, laying the groundwork for development of new treatments for many medical conditions.
For decades, scientists have wondered how living organisms manufacture the essential vitamin B12. Now, using laundry whitener and dirt-dwelling bacteria - everyday ingredients of an undergraduate science experiment - researchers may have found a major clue to solving the mystery.
Researchers in Argentina have determined that night blindness is a new clinical symptom of Chagas disease. They found that the immune systm of individuals with the tropical disease can shut down a key reaction in the retina, causing night blindness.
Using computer-simulated HIV protease molecules, HHMI scientists have identified a potential new drug target for drug-resistant HIV infection.
Researchers studying a lethal canine virus and a related human virus have determined why the canine virus was able to spread quickly from cats to dogs. Their findings provide a new understanding of the molecular factors that enable viruses to jump from one species to another.
The glow emitted by a variety of sea coral helped Russian scientists harness the protein that generates the light to create a tiny fluorescent tag that responds to visible light. The tag should help researchers follow individual proteins as they dart around inside living cells.
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