Connecting Research and Experts with Journalists

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Dor e cãibras nas pernas nem sempre são um problema ortopédico: Ambas podem ser sinais da doença arterial periférica, ou DAP, um grave problema de fluxo sanguíneo com implicações para o coração. Neste alerta do especialista, a Dra. Young Erben, cirurgiã vascular da Mayo Clinic em Jacksonville, Flórida, explica como a forma mais comum da DAP, que afeta as pernas e os pés, é tratada. As opções incluem uma técnica cirúrgica do passado que os cirurgiões da Mayo estão ressuscitando e aperfeiçoando para oferecer uma nova esperança aos pacientes com DAP avançada.

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Dolor y calambres en las piernas no siempre son un problema ortopédico: Ambos pueden ser signos de la enfermedad arterial periférica, o EAP, un problema grave del flujo sanguíneo con implicaciones para el corazón. En este alerta del experto, la Dra. Young Erben, cirujana vascular en Mayo Clinic en Jacksonville, Florida, explica cómo se trata la forma más común de EAP, EAP que afecta las piernas y los pies. Las opciones incluyen una técnica quirúrgica del pasado que los cirujanos de Mayo están resucitando y refinando para ofrecer nuevas esperanzas a los pacientes con EAP avanzada.

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Lactoferrin (LF) is an iron-binding glycoprotein and is involved in important physiological processes. It is derived from milk and mucosal secretions. However, the separation and purification of a large amount of biologically active LF is very difficult. Therefore, technologies for synthetically manufacturing LF are urgently needed. In this review, researchers summarized the design and construction of high-expression LF synthetic biological systems. These systems are efficient and can maximize the LF production at large-scale industrial levels.

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New AI model identifies possible therapies from existing medicines for thousands of diseases, including rare ones with no current treatments. The AI tool generates new insights on its own, applies them to conditions it was not trained for, and offers explanations for its predictions.

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A new paper in Nature Machine Intelligence notes that journal articles reporting how well machine learning models solve certain kinds of equations are often overly optimistic. The researchers suggest two rules for reporting results and systemic changes to encourage clarity and accuracy in reporting.

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Giving women at risk of premature birth a simple magnesium sulphate infusion (or ‘drip’) can prevent their babies from developing cerebral palsy, a recent Cochrane review has confirmed. The drug itself costs approximately £5 (~$6.50) per dose in England, and requires hospital admission with experienced staff to administer the drug safely to the mother.

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Predatory snails drill holes in the shells of their prey. Using these boreholes, a research team led by palaeontologist Martin Zuschin from the University of Vienna was able to create a time series of predator-prey relationships in the northern Adriatic over the past millennia. This showed that human influences led to a collapse in predator-prey relationships from the 1950s onwards.

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This study presents a highly efficient thermal simulation method using a non-gray phonon Boltzmann transport equation. By integrating first-principles phonon properties and advanced computational techniques, the method avoids empirical parameters and achieves remarkable efficiency, solving large-scale 3D problems in under two hours on a personal computer.

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Independent of the temperature and humidity carried by the airflow, portable respiratory sensors are capable of continuously detecting respiratory intensity and frequency. Respiratory monitoring assesses physiological status and potential disease, preventing the escalation of adverse health conditions through early detection of recurrent wheezing, sleep apnoea and diabetes-induced kussmaul breathing.