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A team of researchers led by The Rockefeller University's Alexander Tomasz, Ph.D., have described the case of a 79-year-old patient whose death in a New York metropolitan area hospital last March was associated with a bloodstream infection caused by a multidrug-resistant strain of Staphylococcus aureus.
A single injection of specialized immune system cells can trigger a potent immune response in humans that lasts for months, Rockefeller University researchers report.
Antibiotic resistance in pneumococcus can be stopped by inactivating a pair of genes responsible for producing molecules called branched muropeptides, say Rockefeller researchers (Proceedings of the National Academy of Sciences, 4-25-00).
Research from the Howard Hughes Medical Institute at The Rockefeller University, the Memorial Sloan-Kettering Cancer Center and the State University of New York at Stony Brook shows how the experimental drug STI-571 selectively blocks a mutant enzyme that causes a rare form of leukemia without harming its molecular cousins
One of the most widely disseminated strains of an antibiotic-resistant bacterium responsible for hundreds of infections in European hospitals can be traced back to the 1950s, according to researchers at The Rockefeller University.
Researchers at The Rockefeller University have established a new model to explain how the infectious "staph" bacterium evades several widely used antibiotics. They show that a protein previously thought to play no role in drug resistance in Staphylococcus aureus is, in fact, essential.
How do "killer T cells" know when to attack virus-infected and cancerous cells, and when to retreat? The answer possibly has been provided by Rockefeller University research.
Scientists are now able to "see" a structure that acts as an atomic-size sorter for cells. Without it, many important life functions--nerve signal firing, heartbeat, hormone secretion--could not occur.
Scientists at last may have determined how mental retardation develops in people with fragile X syndrome, a condition caused by the inherited loss of an essential protein, termed the fragile X mental retardation protein (FMRP).
Scientists have turned to nature once again for help in fighting deadly infections. Rockefeller University researchers show that a natural enzyme derived from tiny viruses that live inside bacteria can successfully target and kill disease bacteria, including those that are resistant to drugs.
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