Bad Bitterness Made Better for Everyone: Global Taste Differences in the Flavor of Medicines
Monell Chemical Senses CenterA global Monell Chemical Senses Center examined the bitterness intensity of five medicines and two bitter modifiers in 338 adults of European descent and recent US and Canadian immigrants from Asia, South Asia, and Africa. Bitterness ratings differed by ancestry for two of the five drugs and the effectiveness of some modifiers. Genetic variants also explained some population differences in reaction to bitter tastes.