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David   Braun, MD, PhD

David Braun, MD, PhD

Yale Cancer Center/Smilow Cancer Hospital

Assistant Professor of Medicine (Medical Oncology), Louis Goodman and Alfred Gilman Yale Scholar

Expertise: Cancer ImmunologyKidney CancerCancer ImmunologyMedical OncologyMedical Oncology

David Braun, MD, PhD, is an Assistant Professor of Medicine (Medical Oncology) and a member of the Center of Molecular and Cellular Oncology (CMCO) at Yale Cancer Center. Dr. Braun cares for patients with kidney cancers. He received his PhD in Computational Biology from the Courant Institute of Mathematical Science at New York University and his medical degree from Icahn School of Medicine at Mount Sinai. He completed his residency at the Brigham and Women’s Hospital where he received the Dunn Medical Intern Award and served as Chief Medical Resident before completing fellowship training in adult oncology through the Dana-Farber/Partners CancerCare program where he was appointed the Emil Frei Fellow and the John R. Svenson Fellow.

Dr. Braun joined Yale from Dana-Farber Cancer Institute where he was an Instructor in Medicine with clinical and scientific interest in understanding and improving immune therapies for kidney cancer. He has a longstanding interest in integrating experimental and computational approaches to biomedical research and is currently studying mechanisms of response and resistance to immune therapy in kidney cancer, with the goal of developing novel therapies. He continues this work as part of the CMCO, which fosters and mentors physician-scientists as they advance their laboratory-based research programs to bridge fundamental cancer biology with clinical investigation for the translation of basic discoveries into better treatments or diagnosis.

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Personalized therapeutic vaccine ‘steers’ the immune system to fight kidney cancer

Personalized cancer vaccines (PCVs) train the body’s immune system to recognize and destroy a threat. In this trial, all nine patients who received multiple doses of the vaccine had an immune response within a three-week period and cancer fighting T cells remained elevated for the duration of the study and for years afterward.
03-Feb-2025 08:05:15 AM EST

New Study Unveils Clues to ‘Exceptional’ Response in Metastatic Kidney Cancer Immunotherapy

Metastatic clear cell renal cell carcinoma (mccRCC), an aggressive type of kidney cancer, historically has presented limited treatment options. Immune checkpoint inhibitors, a form of immunotherapy, can lead to exceptional, durable responses (when the tumor substantially shrinks for a very long period of time) for some patients with mccRRC, allowing them to live longer with a better quality of life.
09-Jan-2025 09:05:29 AM EST

Yale Cancer Center Expert to Receive Kidney Cancer Association's Rising Star Award

Dr. David Braun, a medical oncologist at Yale Cancer Center, will be awarded the Christopher G. Wood Rising Star Award by the Kidney Cancer Association at November's International Kidney Cancer Symposium.
25-Oct-2024 02:50:44 PM EDT

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