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Barbara Burtness , MD

Professor of Medicine (Medical Oncology); Chief Translational Research Officer, Yale Cancer Center; Chief, Head and Neck Cancers/Sarcoma; Co-Leader, Developmental Therapeutics, Yale Cancer Center

Yale Cancer Center/Smilow Cancer Hospital

Head And Neck Cancer, Medical Oncology, Sarcoma

Barbara Burtness, MD is a Professor of Medicine (Medical Oncology) at the Yale School of Medicine, Chief Translational Research Officer, and Associate Cancer Center Director for Translational Research at the Yale Cancer Center. She serves as Co-Leader of the Developmental Therapeutics Program, Division Chief for Head and Neck/Sarcoma Oncology, and Director of the Yale Head and Neck Specialized Program of Research Excellence. Dr. Burtness is internationally recognized for her research in head and neck cancer. She chairs the ECOG-ACRIN Cooperative Group Head and Neck Cancer Therapeutics Committee and the ECOG-ACRIN Task Force for the Advanc, and leads national and international trials of targeted therapy in head and neck cancer. Her laboratory studies synthetic lethal therapeutic strategies in head and neck cancer and the targeting of aurora kinase A to overcome adaptive resistance to EGFR inhibition and - in lung cancer- to direct KRAS inhibition. 

Barbara Burtness, MD

Anthony N. Brady Professor of Medicine (Medical Oncology); Chief Translational Research Officer, Yale Cancer Center; Chief, Head and Neck Cancers/Sarcoma; Co-Leader, Developmental Therapeutics, Yale Cancer Center; Associate Cancer Center Director for Translational Research, Yale Cancer Center

Yale Cancer Center/Smilow Cancer Hospital

ASCO 2024, Head And Neck Cancer, Internal Medicine, Medical Oncology

Barbara Burtness, MD, is a Yale Medicine medical oncologist who sees patients at Yale Cancer Center. She has made it her life’s mission to help people diagnosed with head and neck cancer, which can be a devastating disease even after it is cured—it can impact a person’s appearance, as well as the ability to speak, swallow, and eat.

“Patients often encounter unpleasant outcomes that can include difficulty swallowing solid foods, impaired nutrition, aspiration, and feeding tube dependence,” says Dr. Burtness. “Younger patients may have to deal with these side effects for decades after cancer treatment.”

A careful treatment approach can help prevent these problems. She and her team evaluate the tumor location and decide which primary treatment (surgery or radiation therapy) will best cure the cancer and cause the fewest possible negative outcomes.

A professor of medicine at Yale School of Medicine, Dr. Burtness’ research lab is actively studying new cures for head and neck cancers. “We want to help improve these patients’ quality of life,” she says.

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