COVID-19, Ebola, Proteomics, Respiratory Viruses, SARS-CoV-2, Transcriptomics
Dr David Matthews is based in the Department of Cellular and Molecular Medicine at the University of Bristol鈥檚 School of Medical Sciences. He is an expert in zoonotic agents and developed key techniques to apply state of the art 鈥極mics technologies to study viruses in non-human species, notably bat lines infected with the dangerous zoonotic Hendra virus. He led the development of computational pipelines to enable large scale sequencing of Ebola virus genomes in the 2013-2015 Ebola virus epidemic in West Africa. Most recently, he was BBSRC funded to work on Middle East Respiratory Syndrome coronavirus (MERS-CoV), resulting in key research papers that informed discussions in the WHO Covid-19 steering group because of the importance to pre-clinical vaccine trials. Dr Matthews is one of the world鈥檚 leading academics applying high throughput approaches to study infectious disease. His primary focus is on the integration of quantitative transcriptomic and proteomic data, and on building links with clinical colleagues to gain a deeper understanding of how viral infections evolve in an individual host during infection. Education PhD, University of St Andrews