天美传媒

Postdoctoral Training
NIH Postdoctoral Fellowship: University of Arizona (Tucson, AZ)

Fellowship and Affiliations
鈥� Virtual Soldier Research Program (UI Center for Computer-Aided Design, College of Engineering; http://www.ccad.uiowa.edu/vsr/)

鈥� Free Radical & Radiation Biology Program (UI Department of Radiation Oncology, Carver College of Medicine; http://frrbp.medicine.uiowa.edu/)

鈥� Fellow, American Physiological Society (Inaugural Class)

Courses Taught
鈥� 027:130 Human Physiology
鈥� 027:141 Exercise Physiology
鈥� 027:148 Physiology of Aging
鈥� 027:241 Integrative Physiology Seminar
鈥� 050:240 Mechanisms of Human Disease (Carver College of Medicine)

Educational/Research Interests
1. Elucidation of cardiovascular, thermoregulatory, and metabolic mechanisms by which an organism copes with various stresses (e.g., exercise, heat, hypoxia).

2. Factors impacting the changes in stress tolerance (e.g., stress proteins, oxidative stress, metabolic dysfunction) aging, diseased, and healthy young systems.

3. Integration of human physiological testing with physics-based digital human modeling and simulation tools for the development of predictive models for enhanced performance and injury prevention.

Professional Activities
鈥� Collegiate Fellow, College of Liberal Arts & Sciences, University of Iowa

鈥� Associate Editor, Journal of Applied Physiology (http://jap.physiology.org)

鈥� Chair, Animals in Research and Education Subcommittee, FASEB Science Policy Committee (http://www.the-aps.org/mm/hp/Audiences/APS-Committees/sciencepolicy)

鈥� Chair, Science Policy Committee, American Physiological Society (http://www.faseb.org/Policy-and-Government-Affairs/Science-Policy-Issues...)

鈥� Board of Trustees, AAALAC (Association for the Assessment and Accreditation of Laboratory Animal Care, International; http://www.aaalac.org)

Christopher Minson has been performing research on human adaptations to environmental extremes, biomarkers of cardiovascular health, and autonomic-vascular regulation for over 20 years at the University of Oregon. He has consistently been funded through the National Institutes of Health, the American Heart Association, and numerous other funding groups.

The overarching goal of his work is to better understand the basic mechanisms of blood pressure and blood flow regulation, and to find novel ways to improve cardiovascular and metabolic health. He has a long-standing interest in the health benefits of environmental exposure including heat therapy as novel approaches for treatment of cardiovascular and metabolic diseases. Particular areas of interest for Dr. Minson include topics related to women鈥檚 health and aging. He is also interested in the physiology of athletic performance, and has worked with many professional sports teams, Olympic athletes, collegiate and age-group competitive athletes in the U.S. and around the world.

Dr. Minson graduated with a B.S. degree in Psychology from the University of Arizona in 1989. In 1993, he received his Master鈥檚 degree in Exercise Science from San Diego State University. He then went to The Pennsylvania State University where he graduated with a Ph.D. in Exercise Science. He subsequently trained as a post-doctoral fellow at the Mayo Clinic in Minnesota in the Department of Anesthesiology. He has received research awards from the American Physiological Society and the American College of Sports Medicine, Mentor Awards from the Medical Research Foundation of Oregon and the University of Oregon, and was a recipient of a University of Oregon Faculty Excellence Award.

Dr. Minson is Director of the Human Cardiovascular Control Lab and Co-Director of the Exercise and Environmental Physiology Labs. He is also a Founder of the Bowerman Sports Science Center, and serves on the Editorial Boards of the Journal of Applied Physiology, Medicine and Science in Sports and Exercise, and Temperature潞.

Lacy Alexander鈥檚 research utilizes the human cutaneous circulation to examine the underlying signaling mechanisms mediating microvascular dysfunction in diseases, as well as the influence of drug-interventions.

Dr. Alexander utilizes in vivo and in vitro approaches using the human cutaneous circulation to examine the underlying signaling mechanisms mediating microvascular dysfunction with primary human aging, hypercholesterolemia, and essential hypertension.

Education
Ph.D., 2007, Kinesiology, The Pennsylvania State University
M.S., 2002, Human Physiology, University of Oregon
B.S., 2000, Human Physiology and General Science, University of Oregon

Specializations
Mechanisms underlying vascular dysfunction with cardiovascular disease
Pharmacological and lifestyle interventions in vascular dysfunction
Control of human skin blood flow
Grants and Research Projects
Dr. Alexander鈥檚 research interests include examining in vivo and in vitro mechanisms of microvascular dysfunction in cardiovascular disease populations included primary aged, essential hypertension, and hypercholesterolemic humans. Using the cutaneous circulation as a model for examining mechanisms of microvascular dysfunction, the broad focus of her current projects includes examining 1) the roles of arginase in nitric oxide synthase uncoupling in human vasculature with hypercholesterolemia and hypertension, 2) inflammation-induced alteration in vasodilatory signaling with essential hypertension, 3) the role of reactive oxygen species in altering vasoconstriction and vascular remodeling with hypertension, and 4) the effects of common platelet inhibitors (including aspirin and Plavix庐) on microvascular function in human skin as they relate to basic mechanisms of skin blood flow and functional thermoregulatory outcomes.

Assistant Professor with a demonstrated history of working in the higher education industry. Skilled in Cardiovascular Physiology, Human Subjects Research, Data Analysis, Laboratory Skills, and Science Communication. Strong research professional with a Doctor of Philosophy (Ph.D.) focused in Kinesiology from Penn State University.

Area:
Human Physiology
Specialization:
mechanisms of microvascular function and dysfunction, exercise physiology, interventions