Professor - Chair, Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine
University of KentuckyBiochemistry, Virology
Dr. Rebecca Ellis Dutch is a Professor and Chair of the Department of Molecular and Cellular Biochemistry at the University of Kentucky, and currently leads the COVID-19 Unified Research Experts Alliance team focused on biomedical and clinical issues related to the pandemic for the university. Becky received a BS in Biochemistry and a BS in Microbiology from Michigan State University in 1986. As a Churchill Scholar, she then completed a M.Phil. degree in Biochemistry from Cambridge University, focusing on plant biochemistry. She received her Ph.D. in Biochemistry from Stanford University in 1994, working with Dr. I. Robert Lehman on recombination in herpes simplex virus. Becky then moved to studies of viral glycoproteins in RNA viruses for her postdoctoral training at Northwestern University/HHMI with Dr. Robert Lamb. She joined the faculty of the University of Kentucky in 2000. Her research, which has resulted in continuous NIH funding since 2001 and numerous other grants, manuscripts, and presentations focuses on emerging RNA viruses, with a particular emphasis on viral entry, assembly, and spread. Dr. Dutch was a 2015-2016 University Research Professor in recognition of her outstanding research efforts. Dr. Dutch teaches at both the undergraduate and graduate level and has twice been named a finalist for the Provost’s Outstanding Teacher award. She is also highly committed to the training and mentoring of young scientists and has served as the primary mentor for 19 Ph.D. students, 4 MD/Ph.D. students, five postdoctoral scholars, and 28 undergraduate researchers. Dr. Dutch is an editor for Journal of Virology (where she also serves as the Spotlight editor), Plos Pathogens, and mSphere. She has been a member of numerous grant review panels, including serving as a standing member of the NIH VIRB and MID study sections. She also served as the elected President of the American Society for Virology from 2016-2017.
Associate Professor, Molecular Biosciences
University of Texas at Austin (UT Austin)Biochemistry, Biophysics, Drugs, Immunology
Jason McLellan specializes in understanding the structure and function of viral proteins, including those of coronaviruses. His research focuses on applying structural information to the rational design of vaccines and other therapies for viruses, including SARS-CoV-2, the novel coronavirus that causes COVID-19. McLellan and his team collaborated with researchers at the National Institute of Allergy and Infectious Diseases’ Vaccine Research Center to design a stabilized version of the SARS-CoV-2 spike protein, which forms the basis of several leading COVID-19 vaccine candidates, including those by Moderna, Novavax, Johnson & Johnson and Pfizer/BioNTech. Dr. McLellan earned a BS in chemistry with an emphasis in biochemistry from Wayne State University in Detroit, Michigan. Afterward, he obtained his PhD from the Johns Hopkins University School of Medicine in Baltimore, Maryland in the laboratory of Dr. Daniel Leahy. He then carried out postdoctoral research at the National Institutes of Health's Vaccine Research Center in the laboratory of Dr. Peter Kwong and in collaboration with Dr. Barney Graham. In the Fall of 2013, he joined the faculty at the Geisel School of Medicine at Dartmouth in the Department of Biochemistry, and in January 2018 he moved his laboratory to the University of Texas at Austin and became a member of the Department of Molecular Biosciences. Awards: 2020 William Prusoff Memorial Award (International Society for Antiviral Research) 2019 Viruses Young Investigator in Virology Prize 2018 American Crystallographic Association Etter Early Career Award 2015 Charles H. Hood Foundation Child Health Research Award 2012 Norman P. Salzman Memorial Award in Virology
Distinguished Professor, Chemistry
University at Albany, State University of New YorkBiochemistry, Biophysics, Chemistry
Biochemistry, Chemistry, Data Analysis, Molecular Biology
Dr. Chaevien Clendinen is an analytical chemist with the Biomolecular Pathways team. She is an expert in metabolomics data analysis and workflow development using a variety of analytical pipelines, including liquid chromatography mass spectrometry (LC-MS), gas chromatography MS (GC-MS), and nuclear magnetic resonance (NMR) spectroscopy. She is also an expert in structural elucidation using LC-MS and NMR.
Clendinen has 10 years of research experience across multiple disciplines, including analytical and physical chemistry, microbiology and virology, cancer biology, and biotechnology. At EMSL, Dr. Clendinen assists users in the collection and analysis of metabolomics data from a variety of sample matrices. She is currently working with PNNL researchers to improve LC, GC, and NMR metabolomics workflows and identification confidence.
Lecturer, RIPE Principal Investigator
Realizing Increased Photosynthetic Efficiency (RIPE) ProjectBiochemistry, Photosynthesis
Amanda Cavanagh is a lecturer at the University of Essex. She is interested in the biochemical diversity in plants and how this diversity can affect photosynthesis and plant growth. Her research for RIPE involves characterizing the biochemistry and physiology of RIPE's work in plants. Amanda's work has been published in Plant Cell, Photosynthesis Research, and . Learn more about Amanda's breakthrough work that boosted crop growth by 40 percent on , or watch the video below. Amanda joined the RIPE project as a postdoctoral researcher at the University of Illinois in the lab of Don Ort.
Amanda earned her bachelor's degree in biology and chemistry and went on to earn her doctorate in biology from the University of New Brunswick. As a doctoral student, she was independently awarded funding from the Natural Sciences and Engineering Research Council of Canada and as well as an award from the O'Brien Foundation, a humanitarian trust. Amanda also received the 2021 Rank Prize New Lecturer grant in nutrition, having been one of three scholars to receive the award.
Biomedical Scientist
Environmental Molecular Sciences Laboratory - EMSLBiochemistry, Lipidomics, Mass Spectrometry, Metabolomics, Proteomics
Dr. Kristin Burnum-Johnson is a senior scientist and an expert with the Integrated Research Platform. Burnum-Johnson earned her PhD in Biochemistry from Vanderbilt University with Professor Richard M. Caprioli and then completed a postdoctoral fellowship at PNNL with Dr. Richard D. Smith.
Critical challenges in systems biology, ranging from environmental sustainability to human health, may be addressed through the comprehensive and informative view of underlying biological pathways provided by the integration of spatiotemporal multi-omic measurements (i.e., proteomics, metabolomics, and lipidomics). Her research is dedicated to achieving transformative molecular-level insights into environmental and biomedical systems by implementing advanced mass spectrometry (MS) instrumentation. Burnum-Johnson has over a decade of experience and more than 50 publications dedicated to the development and evaluation of in situ imaging MS, structural characterization of molecules using ion mobility-MS, and analyses of molecules in complex matrices using high-resolution MS. Her research program is funded by the U.S. Department of Energy (DOE) Biological and Environmental Research (BER) program, the DOE Bioenergy Technologies Office (BETO), and the National Institutes of Health (NIH).
Burnum-Johnson was selected to receive a 2019 Early Career Research Program Award from DOE’s Office of Science. As part of her DOE BER early career research program, she is applying a multi-omics approach to uncover the mechanisms that drive cooperative fungal-bacterial interactions that result in the degradation of lignocellulosic plant material in natural ecosystems. Insights obtained from these studies inform new strategies for producing advanced bioproducts and biofuels.
Biochemistry, Cell Biology, Cognitive Sciences, Neuroscience, Psychology
Research in the Maguire lab takes a systems physiology approach to studying the mechanisms contributing to neurological and neuropsychiatric diseases, with a focus on epilepsy and mood disorders. Our research has explored the impact of the neuroendocrine system on the comorbidity of epilepsy and depression as well as the role in postpartum depression. Working from the vantage point of synaptic changes, such as GABAergic dysregulation, to circuit dysfunction between the prefrontal cortex and the amygdala, to in vivo changes in excitability and behavior, we have explored many mechanistic levels contributing to neurological and neuropsychiatric diseases. We have incorporated cutting edge tools into our research program, where appropriate, to study the contribution of specific cell types and circuits in mediating physiological and pathological processes. Based on our discovery of neurosteroid-mediated alterations in GABAA receptor subunit expression during pregnancy and the postpartum period and our theory for a potential role in postpartum depression, a company designing neurosteroid-based treatment approaches embarked on a series of successful clinical trials for the treatment of postpartum depression. Our discoveries have also generated two useful mouse models of postpartum depression, leading to a collaboration with SAGE Therapeutics to perform preclinical studies on the underlying mechanisms and treatment options for postpartum depression. Our basic research program is also actively investigating the mechanisms of hypothalamic-pituitary-adrenal (HPA) axis regulation during the peripartum period and the contribution of dysregulation of the HPA axis in abnormal postpartum behaviors. Our research has also discovered a novel mechanism contributing to epilepsy progression and associated comorbidities, involving dysfunction in the regulation of the HPA axis. This work has carved out a niche in the field, establishing our lab as experts in this area. This work also earned two competitive research grants (RO1s) from the National Institutes of Health to fund this work. Our lab is presenting investigating the pathological consequences of seizure-induced activation of the HPA axis, focusing on the role of hypercortisolism in seizure susceptibility and associated comorbidities.
Waldemar Von Zedtwitz Professor of Genetics and Professor of Molecular Biophysics and Biochemistry and of Therapeutic Radiology; Deputy Director, Yale Cancer Center
Yale Cancer Center/Smilow Cancer HospitalBiochemistry, Genetics, Molecular Biophysics, Therapeutic Radiology
The DiMaio laboratory is studying the molecular mechanisms of how human papillomaviruses enter cells, with a particular focus on identifying the cellular proteins that mediate virus entry and intracellular trafficking and determining their molecular mechanisms of action. In addition, it is using viral transmembrane proteins as a basis to develop a class of artificial small transmembrane proteins with a variety of biological activities, including the ability to form tumors and confer resistance to virus infection. Some of these proteins are the simplest proteins ever described and their study will reveal new features of protein action and the basis for specificity in protein-protein interactions.
Biochemistry, Chemistry, Geochemistry, Geology
Usha Rao is a recipient of the Association for Women in Science’s Zenith award, a lifetime leadership and achievement award. She has also received the Distinguished Research Lectureship from the Association for Women Geoscientists, and the Bingham Mentoring Award from the Philadelphia chapter of AWIS, awarded to a “distinguished scientist who has significantly influenced the advancement of women in science”. Dr. Rao was selected by Pennsylvania Governor Wolf to participate in the 'PA Women in STEM' video series. She serves as a writer and speaker on the environment, leadership, and mentoring for many US and international organizations. Some recent partners include the Chronicle of Higher Education, the Swiss National Science Foundation's PRIMA Program, the American Association for Environmental Engineering and Science, and Lab Manager magazine.
Dr. Rao's STEM teaching has been recognized with the Lindback Foundation's Christian R. and Mary F. Lindback Medal for Distinguished University Teaching. She has also received three merit awards for "exceptional achievement in teaching" at Saint Joseph's University and was selected as a Most Valuable Professor (MVP) by the women's basketball team.
At Saint Joseph's, Dr. Rao co-developed the John P. McNulty Program for Leadership in Science and Mathematics, an initiative that has supported 130 emerging leaders since 2009. She also created the University’s first faculty development office to provide resources and mentoring to hundreds of faculty members, serving as the Founding Director. Dr. Rao’s board service includes the Ardmore Library of the Lower Merion Library System and the Frances M. Maguire Art Museum at the Barnes Foundation in Lower Merion.
Dr. Rao’s research focuses on water chemistry. She is a coordinating editor for Springer-Nature's Environmental Geochemistry and Health, the journal of the Society for Environmental Geochemistry and Health. She serves as an Approved Expert Reviewer for the Nobel-prize winning United Nations’ Intergovernmental Panel on Climate Change (UN IPCC) and as a Mentor for former US Vice President Gore’s Climate Reality initiative.
Her research at SJU has been funded by the National Science Foundation, the American Chemical Society Petroleum Research Fund, the Lindback Foundation Minority Research Program, Purdue University’s PRIME particle accelerator laboratory, the Michael J. Morris Grant Program, and Saint Joseph’s University Board on Faculty Development and Research. She is currently accepting queries from graduate students.
Professor
Realizing Increased Photosynthetic Efficiency (RIPE) ProjectBiochemistry, Biosynthesis, CRISPR, crispr cas9, Photosynthesis, Plant Biology, Plant Genetics
Professor Kris Nyogi is the Associate Chair of the Department of Plant and Microbial Biology at the University of California, Berkeley. Kris is also a faculty scientist in the Physical Biosciences Division at Lawrence Berkeley National Laboratory. He received his bachelor’s degree in biology at Johns Hopkins University, his master’s degree in biochemistry from the University of Cambridge, and he received his doctorate in biology from the Massachusetts Institute of Technology. He has been given multiple awards including: the Howard Hughes Award, the Charles Albert Schull Award from the American Society of Plant Biologists, and the Melvin Calvin Award from the International Society of Photosynthesis Research. In 2016, Kris was elected to the National Academy of Sciences and in 2020, he was recognized by the Web of Science group as 2020's Highly Cited Researchers, an achievement earned by those who have published multiple papers ranking in the top 1% by citations across 21 disciplines. Kris studies how photosynthetic energy conversion works, how it is regulated, and how it might be improved. His research focuses on the biosynthesis and function of photosynthetic pigments, assembly of photosynthetic reaction centers, structure and dynamics of the photosynthetic membrane, mechanisms involved in sensing excess light, and regulation of photosynthetic light harvesting in saturating light.
Biochemistry, Geroscience, Molecular Biology
Dr. Sierra’s career has spanned academia, industry and government, including his role as Director of the Division of Aging Biology at the NIA/NIH, from 2006 to 2019, where he was an important contributor to the development of the concept of Geroscience, including the creation and leadership of the trans-NIH Geroscience Interest Group (GSIG). Before joining Hevolution in 2022, he was Director of Geroscience for Inspire.
Dr. Sierra holds a Ph.D. in Biochemistry and Molecular Biology from the University of Florida and was an Assistant Professor at the Medical College of Pennsylvania, and an Associate Professor at the Lankenau Institute for Medical Research in Pennsylvania.
Professor of Microbiology
College of Liberal Arts and Sciences, University of Illinois Urbana-ChampaignBacteria, Bacterial Resistance, Biochemistry, Biologics, Biosecurity, Biotechnology, Genomics, host-pathogen interactions, Infectious Diesease, Microbiology, Microbiome, one health, Pathogenesis, Protein Engineering, Toxins
Brenda Anne Wilson is a Professor of microbiology in the School of Molecular & Cellular Biology at the University of Illinois Urbana-Champaign. She also is the Inaugural Professor of Biomedical and Translational Sciences in the Carle Illinois College of Medicine, an adjunct professor of pathobiology in the College of Veterinary Medicine; and the Sandia Senior Faculty Fellow in the university's Office of the Vice Chancellor for Research and Innovation.
Wilson is a fellow of the American Academy of Microbiology and a member of the AAM Selection Committee, and an American Society for Microbiology Distinguished Lecturer.
She was a DAAD graduate exchange Fellow in biochemistry at Ludwig-Maximilians Universität München, Germany. While earning her PhD at Johns Hopkins University, she was an AAUW doctoral fellow and studied antibiotic biosynthesis. She then undertook her NIH postdoctoral fellowship training in microbiology at Harvard Medical School, where she began her studies on bacterial protein toxins. Her first tenured faculty appointment was in biochemistry at Wright State University School of Medicine, Dayton, Ohio.
As inaugural leader of the Host-Microbe Systems Theme of the Woese Institute for Genomic Biology at the University of Illinois for 10 years, Wilson brought together faculty and scientists from multiple disciplines across campus, including microbiology, anthropology, animal sciences, engineering, and veterinary pathobiology to forge new areas of microbiome research. She served for 10 years on the executive committee of the Great Lakes Regional Center for Excellence in Biodefense and Emerging Infectious Diseases. As co-director of the University of Illinois Center for Zoonoses Research, she has promoted the One-Health Initiative and training of DVM students in research through summer training experiences. For nearly 20 years she has served as Biosecurity Leader of the Executive Committee of the University of Illinois Program in Arms Control, Domestic and International Security, where she has engaged events promoting scientific literacy and bridging the gap between scientists and educators, policy makers, government officials, and the public.
Wilson is currently president of the Champaign-Urbana Branch of the American Association for University Women, where she helps organize and convene community outreach events aimed at advancing equity and higher education opportunities for women and girls, particularly in STEM areas. As director for undergraduate education in the School of Molecular and Cellular Biology, she helps oversee the delivery of all academic, advising, and curricular aspects of the BS in MCB, BS in Biochemistry, BS in Neuroscience, and the forthcoming BS in MCB + Data Science undergraduate programs and the MS in MCB graduate programs. As the Sandia Senior Faculty Fellow in the Office of the Vice-Chancellor for Research and Innovation, she fosters, engages, and sustains research collaborations in STEM disciplines, including building workforce pipelines between scientists at the University of Illinois and the U.S. Department of Energy's national labs.
Research interests
Wilson’s research focuses on the host-microbe interface, bacterial pathogenesis and bacterial protein toxins, development of anti-toxin and toxin-based therapeutic biologics, comparative and functional genomic technologies and applications involving microbiomes and their roles in health and disease, climate change impacts on microbiomes, health, and disease transmission, and development of technologies and applications for detection and risk assessment of Dual Use Research of Concern (DURC) objects, publications, and activities. She has published over 150 scientific articles, chapters, and books, including the highly acclaimed textbook Bacterial Pathogenesis: A Molecular Approach (4th Edition, 2019, ASM Press/John Wiley) and the recent Revenge of the Microbes: How Bacterial Resistance is Undermining the Antibiotic Miracle (2nd Edition, 2023, ASM Press/John Wiley).
Education
BA (Biochemistry and German), Barnard College/Columbia University, 1981
Biochemistry Diplomarbeit (Post-baccalaureate Program), Deutscher Akademischer Austauschdienst (DAAD), Ludwig-Maximilians Universität, Munich, Germany, 1981-1982
M.S./Ph.D. (Chemistry), Johns Hopkins University, 1989
Postdoctoral (Microbiology and Molecular Genetics), Harvard Medical School, 1989-1993
Website
Biochemistry, Biomedical Science, chronic inflammatory disease, Coronary Artery Disease, Diabetes, Epigenetics, lifestyle medicine, Metabolism, MicroRNA, mycotoxins
Professor Alisa Phulukdaree's work takes place at the basic molecular and cellular levels, which evaluates how genetic differences influence the risk of getting type 2 diabetes and heart disease between ethnic groups including people of Caucasian, African and Indian descent. These findings impact society by creating an awareness of the differences that exist. Thus by educating society, they can make informed decisions in their lifestyle choices.
Her teaching responsibilities include knowledge dissemination in medical biochemistry and molecular mechanisms of disease at undergraduate, postgraduate and postdoctoral levels.