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Anne Bang Joins $12.7M Research Project on the Genetic Basis of Autism and Schizophrenia

Scientists have linked neuropsychiatric disorders, such as schizophrenia and autism, to changes in many genes involved in early brain development. However, more research is needed to understand how these gene variants influence the biological...
11-Oct-2024 1:05 PM EDT Add to Favorites

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How to Build Our Body’s Protein Recycling Factories

Scientists at Sanford Burnham Prebys have developed a clearer picture of how crucial machinery in the human cell’s recycling process for obsolete and misshapen proteins—known as proteasomes—are formed.
26-Sep-2024 4:05 PM EDT Add to Favorites

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Macrophage mix helps determine rate and fate of fatty liver disease

Formerly known as nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis (MASH) is an inflammatory disease characterized by liver scarring or fibrosis that progressively impairs liver function. It is a major risk factor...
22-Aug-2024 3:05 PM EDT Add to Favorites

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The secret to sleepy cells’ control of inflammatory secretions

Scientists at Sanford Burnham Prebys and the La Jolla Institute for Immunology have revealed a new secret regarding senescence, a cellular state similar to sleep that is more likely to affect aged cells.
22-Aug-2024 1:05 PM EDT Add to Favorites

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Controlling thickness in fruit fly hearts reveals new pathway for heart disease

Scientists at Sanford Burnham Prebys and Salk Institute for Biological Studies have uncovered a new role for a protein known for its role in the brain helping control feelings of hunger or satiety, as well as in the liver to aid the body in...
2-Aug-2024 1:05 PM EDT Add to Favorites

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Ze’ev Ronai steps down as cancer center director at Sanford Burnham Prebys

Ze’ev Ronai, PhD, is stepping down as director of the National Cancer Institute-designated cancer center at Sanford Burnham Prebys, effective August 1. Cosimo Commisso, PhD, deputy director of the cancer center, will serve as interim head while a...
30-Jul-2024 1:05 PM EDT Add to Favorites

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Mini lungs make major COVID-19 discoveries possible

Scientists at Sanford Burnham Prebys, University of California San Diego and their international collaborators have reported that more types of lung cells can be infected by SARS-CoV-2 than previously thought, including those without known viral...
23-Jul-2024 2:05 PM EDT Add to Favorites

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How a protein component of nuclear pore complexes regulates development of blood cells and may contribute to myeloid disorders

Nuclear pore complexes (NPCs) are channels composed of multiple proteins that ferry molecules in and out of the nucleus, regulating many critical cellular functions, such as gene expression, chromatin organization and RNA processes that influence...
5-Jun-2024 5:05 PM EDT Add to Favorites


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Xueqin Sun seeks to illuminate the underlying causes of cancer

As a new assistant professor at Sanford Burnham Prebys faculty, Sun seeks to better understand the genetic and epigenetic underpinnings of cancers, using genome editing technologies, animal and patient-derived models, and other tools to develop more...
13-Mar-2024 9:05 AM EDT

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Sanjeev Ranade wants to get to the heart of congenital disease

Sanjeev S. Ranade, Ph.D., who joined the faculty of Sanford Burnham Prebys this month as an assistant professor in the Development, Aging and Regeneration program, studies how proteins called transcription factors (TFs) specifically control the...
22-Jan-2024 6:00 AM EST

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When T cells and macrophages talk, Kelly Kersten listens

Kelly Kersten, Ph.D., who joined Sanford Burnham Prebys this month as an assistant professor in the Cancer Metabolism and Microenvironment program, studies the interactions between immune cells and their microenvironment to better understand how...
17-Jan-2024 2:05 PM EST

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Shengjie Feng channels the powers of cryogenic electron microscopy

Shengjie Feng, Ph.D. is an expert in cryo-electron microscopy, a Nobel Prize-winning imaging technology capable of creating stop-action movies of proteins and other biomolecules jostling and connecting with each other while mitochondria and other...
16-Jan-2024 12:05 PM EST

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Fighting Against Triple-Negative Breast Cancer

2-Oct-2017 8:00 AM EDT

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Brrrr...it's WINTER. Can Being Cold Really Help You Burn Calories and Slim Down? An #SBP Researcher Weighs In

31-Jan-2017 2:05 PM EST

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Could Fake Sugar Cause Real Problems with Your Metabolism? An @SBPdiscovery Researcher Wants to Find Out

7-Nov-2016 8:00 AM EST

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To Treat Breast Cancer, Give It a Lifeline

19-Oct-2016 12:05 PM EDT

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About

Sanford Burnham Prebys is an independent biomedical research institute dedicated to understanding human biology and disease and advancing scientific discoveries to improve human health. For over 40 years, our research has produced breakthroughs in cancer, neuroscience, immunology and children’s diseases, and is anchored by our NCI-designated cancer center and advanced drug discovery capabilities. For more information, visit us at SBPdiscovery.org or on Facebook at facebook.com/SBPdiscovery and on Twitter @SBPdiscovery.

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