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New Technique Reveals How the Same Mutations Give Rise to Very Different Types of Leukaemia

• A study from IRB Barcelona, funded by Fundación CRIS contra el cáncer demonstrates that the “previous state” of blood stem cells plays a decisive role in the subtype of leukaemia that develops. • The new technique, called STRACK, allows...
24-Feb-2025 11:30 AM EST Add to Favorites

Researchers Discover An Origin of Idiopathic Autism

A study by IRB Barcelona unveils how the lack of a fraction of the CPEB4 protein causes a decrease in the expression of genes that are crucial for neuronal development. Published in the journal Nature, the study opens new avenues for the development...
30-Nov-2024 9:30 AM EST Add to Favorites

Synchronisation between the central circadian clock and the circadian clocks of tissues preserves their functioning and prevents ageing

• Two complementary research articles, published simultaneously in the journals Science and Cell Stem Cell by a team of scientists from the UPF and IRB Barcelona, reveal that central and peripheral circadian clocks coordinate to regulate the daily...
1-May-2024 3:05 PM EDT Add to Favorites

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Researchers observe at the atomic level the neuronal 'gate' for essential molecules in learning and memory

The protein Asc-1 serves as the gateway (either for entry or exit) for fundamental amino acids involved in cognitive processes. A new study now unveils its structure and mechanism of action.
17-Apr-2024 4:05 AM EDT Add to Favorites

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Characterization of mutational “coldspots” in the cancer genome

Researchers at IRB Barcelona report mutation rate variation across the human genome. Regions with low mutation rates correlate with hypomethylation (low methylation levels), a way cells control which genes are turned on or off.
10-Apr-2024 9:05 AM EDT Add to Favorites

Researchers from IRB Barcelona and Sant Joan de Déu unveil the origin of second pediatric cancers and chemotherapy-induced mutations in healthy tissues

A team from IRB Barcelona and Sant Joan de Déu Hospital · IRSJD has studied the cases of four children who have experienced two cancers during childhood and has addressed the origin of the second tumour.
18-Mar-2024 7:05 PM EDT Add to Favorites

Launch of a pioneering translational research programme in Europe

- The TRIP initiative establishes three new joint laboratories that bring together fundamental biomedical research and clinical research with the aim of accelerating the delivery of results to patients. - TRIP will focus on emerging fields such as...
6-Mar-2024 8:05 AM EST Add to Favorites


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About

We are a biomedical research center that works to achieve a society free of diseases. Our mission is to carry out research of excellence to cure cancer and other diseases linked to ageing.

Our research results reach patients through technology transfer, which is accomplished by establishing collaborations with the pharmaceutical industry and the main hospitals.
We are also committed to knowledge. To this end, we offer the best training in biomedical sciences to young researchers, students and visitors, and maintain an open dialogue with citizens through a range of scientific communication and outreach activities.
IRB Barcelona was founded in 2005 by the “Generalitat de Catalunya” and the University of Barcelona (UB) and is located in the Barcelona Science Park (PCB). We are a CERCA centre that forms part of the Barcelona Institute of Science and Technology (BIST). The State Research Agency has awarded IRB Barcelona four consecutive Severo Ochoa" Centre of Excellence Accreditations (2011, 2015, 2019 and 2023).

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