In a new analysis of national data, researchers at the Richard A. and Susan F. Smith Center for Outcomes Research at Beth Israel Deaconess Medical Center (BIDMC) estimated that 137 million U.S. adults, more than half of all adults, are eligible for semagludtide for weight loss, diabetes management, or prevention of recurrent cardiovascular events.
In a nationwide observational study published this month in The Journal of the American Medical Association (JAMA), cardiologists from the Smith Center for Outcomes Research at Beth Israel Deaconess Medical Center (BIDMC) were commissioned by the U.S. Food and Drug Administration (FDA) to examine trends in the use and long-term safety of a device widely used to treat pulmonary embolism, or blood clots in the lungs.
OpenNotes, an international leader in health transparency research at Beth Israel Deaconess Medical Center (BIDMC), and Abridge, a leading generative AI platform for clinical documentation, launched a partnership that will bring patient-clinician conversations to the forefront of research to enhance patient notes.
Cardiovascular disease (CVD) is the primary cause of death among adults over age 65 years. Seniors are also likely to have low blood levels of Vitamin D, which has been linked to cardiovascular disease. Despite this, many observational trials have not demonstrated that Vitamin D supplementation reduces cardiovascular disease risk.
A study led by Adam Rodman, MD, MPH, Director of AI Programs at Beth Israel Deaconess Medical Center (BIDMC), reveals that, rather than helping to reduce racial and ethnic biases, AI-driven chatbots may instead perpetuate and exacerbate disparities in medicine.
Research shows people previously vaccinated against mpox in 2022 had declining antibody responses after six to 12 months, as World Health Organization (WHO) designates the 2024 mpox outbreak a public health emergency of international concern.
In a study of 12 participants, researchers at Beth Israel Deaconess Medical Center (BIDMC) have demonstrated that a cocktail of three broadly neutralizing antibodies (bNAb) successfully suppressed virus in people living with HIV. A subset of participants also demonstrated long-term control of the virus months after antibody levels declined to low or undetectable.
A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) found the risk of developing Parkinson’s disease was 76 percent higher among those with a history of damage to the lining of their upper gastrointestinal (GI) tract than among those without.
Rohit N. Kulkarni, MD, PhD, the Diabetes Research and Wellness Foundation Endowed Chair and Co-Head of the Section on Islet & Regenerative Biology at Joslin Diabetes Center, has been awarded $9,920,607 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health (NIH).
Cardiovascular disease (CVD) is the leading cause of death worldwide, accounting for approximately one in every three deaths, with more than 20 million deaths reported in 2021 according to a 2024 World Heart Federation report.
Investigators used machine learning approaches to integrate high-throughput transcriptomic, proteomic, metabolomic, and lipidomic profiles to provide novel critical molecular insights into Alzheimer’s Disease (AD) that single-omic analyses cannot offer.
One of the most common genetic heart diseases worldwide, hypertrophic cardiomyopathy (HCM) causes the walls of the left ventricle to become thick and stiff. In about 70 percent of cases, patients with HCM experience obstruction to blood flow, which increases pressures in the heart and can lead to chest pain, shortness of breath and reduced exercise capacity.
ChatGPT-4, an artificial intelligence program designed to understand and generate human-like text, outperformed internal medicine residents and attending physicians at two academic medical centers at processing medical data and demonstrating clinical reasoning. In a research letter published in JAMA Internal Medicine, physician-scientists at Beth Israel Deaconess Medical Center (BIDMC) compared a large language model’s (LLM) reasoning abilities directly against human performance using standards developed to assess physicians.
In a paper published in the Journal of the American Medical Association (JAMA), neurologists at Beth Israel Deaconess Medical Center (BIDMC) showed that a simple skin biopsy test detects an abnormal form of alpha-synuclein, the pathological hallmark of Parkinson’s disease and the subgroup of neurodegenerative disorders known as synucleinopathies, at high positivity rates.
In the largest randomized clinical trial and first of its kind to date in the United States, a team led by investigators at Beth Israel Deaconess Medical Center (BIDMC) assessed the efficacy and safety of using a drug-coated balloon in patients undergoing coronary angioplasty.
A landmark study conducted at four sites, including Joslin Diabetes Center, reports that people with type 2 diabetes who underwent bariatric surgery achieved better long-term blood glucose control compared to people who received medical management plus lifestyle interventions. Participants who underwent bariatric surgery, also called metabolic or weight-loss surgery, were also more likely to stop needing diabetes medications and had higher rates of diabetes remission up to 12 years post-surgery. The findings, published in JAMA, suggest that weight loss surgery may carry benefits for people with diabetes, even those who are below the traditional BMI threshold of 35 for bariatric surgery.
About eight million people live with Type 1 diabetes (T1D) worldwide, a chronic autoimmune condition in which the body attacks and destroys its own insulin-producing β-cells (pronounced “beta”) in the pancreas, leading to a lack of insulin and inability to regulate blood sugar. It’s not known why the body suddenly perceives its own β-cells as the enemy; some lines of evidence suggest environmental factors such as viral infections may trigger the onset of T1D, others suggest genetics may also play some role. Groundbreaking research by investigators at Joslin Diabetes Center sheds new light on the specific changes β-cells go through at the onset of T1D. Their findings—published in Nature Cell Biology—offer new avenues for targeted interventions for the chronic autoimmune condition.
Findings published in the journal Nature by physician-scientists at Beth Israel Deaconess Medical Center (BIDMC) and colleagues suggest that it may be possible to improve protection against COVID-19 by delivering the vaccine directly to the respiratory tract— the primary site of entry in SARS-CoV-2 infection.
Physician-investigators compared a chatbot’s probabilistic reasoning to that of human clinicians. The findings, published in JAMA Network Open, suggest that artificial intelligence could serve as useful clinical decision support tools for physicians.
New research helps explain the recent reversal in cardiovascular mortality among this population and underscores the need to address the social determinants of health that contribute to it.
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