Receiving a liver transplant means also living with the possibility of rejection. Transplant rejection occurs when the body’s immune system attacks the new organ. This risk is highest in the first year after the transplant, but rejection can happen at any time. To prevent this, patients take powerful medications to suppress their immune system and reduce inflammation.
In 2022, a team from Children’s Hospital Los Angeles became the first in the world to implant a novel cardiac stent designed specifically for babies and young children. The stent is the first of its kind that can be expanded as a child grows—all the way to adult size.
It’s challenging to achieve significant curve correction during a spinal fusion “graduation” surgery for children with early onset scoliosis. Over the years, bone auto-fuses and stiffens around growing rods—making the spine tougher to straighten during this final procedure.
For many students, summer break represents an opportunity for relaxation and carefree vacations. But for the medical students taking part in the USC/CHLA Summer Oncology Research Fellowship (SORF) Program, summer means something more
In the U.S. alone, more than 3.5 million babies are born each year. Alongside them, an endlessly fascinating organ that’s essential to a healthy pregnancy: the placenta.The placenta forms early in pregnancy, providing a vital connection between baby and mom. Then, it’s delivered shortly after the baby during childbirth, and its job is complete.
Pediatric heart failure is a progressive and life-threatening condition that can have a high mortality rate. Fortunately, thanks to new therapies now available, many children can recover—but this condition needs early recognition and treatment.
Advances in radiation therapy have provided groundbreaking innovations in treating children with brain tumors. Treatment methods are increasingly more precise to avoid damaging surrounding healthy tissue. Still, radiation therapy is not without risk, especially in an area as sensitive as the brain.
Mallory Chavannes, MD, MHSc, FRCPC, FAAP, Clinical Director of the Inflammatory Bowel Disease Program at Children’s Hospital Los Angeles, has co-written “AGA Clinical Practice Update on the Role of Intestinal Ultrasound in Inflammatory Bowel Disease: Commentary,” a new clinical practice update from the American Gastroenterological Association (AGA) Institute.
Every cell in your body holds a unique genetic code within your DNA, inherited from your parents. The segments of your DNA called genes determine nearly all your body’s characteristics and functions.
Three years ago, Jessica Sheth Bhutada, MD, was researching rates of metastatic cancer in adolescents and young adults (AYAs) when she noticed a disturbing trend.
In the pediatric world, cancer survivorship programs have become a critical part of patient care over the past 30 years. These programs were a response to rising childhood cancer five-year survival rates—now over 85%—and to late effects (health problems caused by the cancer or cancer treatments).But for adults with cancer—including young adults—survivorship care has not been nearly as well developed or implemented.
Researchers at Children’s Hospital Los Angeles and their collaborators in a nationwide study report that they have identified the most common long-COVID symptoms experienced by children ages 6 to 17 years old—and that they can objectively distinguish these symptoms by age.
Germ cell tumors have been treated with cisplatin-based chemotherapy since the 1970s. While approximately 80% of patients respond well to cisplatin, the remaining 20% do not.For those patients, treatment options are limited, and when the cancer returns after second- and third-line treatments, cancer-related mortality is over 90%.
A new study led by Children’s Hospital Los Angeles found wide variation in pediatric inpatient psychiatric beds across the United States. It highlights the growing concerns about the demand and access to mental health services for children and the geographic disparities in the availability of inpatient psychiatric care.
A team led by a Children’s Hospital Los Angeles heart surgeon has received a patent for a novel device design that could solve a pressing problem: how to bridge patients with a Fontan circulation to heart transplant.
This spring, Children’s Hospital Los Angeles became one of just 15 pediatric hospitals in the country to be designated as a TSC Alliance Center of Excellence—demonstrating the highest level of comprehensive services for diagnosing and managing tuberous sclerosis complex (TSC). CHLA sees more than 120 young patients a year with TSC.
For 19 years, LA-HIP has empowered rising high school seniors who identify as an underrepresented minority in STEM to participate in hands-on laboratory-based research at CHLA. The program’s ultimate goal: To develop and nurture the next generation of scientists and physician-scientists.
Preterm birth accounts for nearly a quarter of mortality in babies with congenital diaphragmatic hernia (CDH), according to a new study from Children’s Hospital Los Angeles.The study, led by Kuan-Chi Lai, MD, MPH, found that, at a population level, 24% of mortality in babies with CDH can be attributed to being born premature.
Children’s Hospital Los Angeles has named James F. Amatruda, MD, PhD, a highly respected medical leader, clinician, and researcher with global recognitions, as Director of the Cancer and Blood Disease Institute and Alfred E. Mann Family Foundation Chair in Cancer Research at Children’s Hospital Los Angeles
Neonatal shock is an acute and potentially life-threatening condition for babies. To treat it, physicians must determine whether systolic or diastolic dysfunction—or both—is causing a lack of oxygen to the baby’s organs.But that’s not always a simple task.
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