Changes in brain connectivity before and after puberty may explain why some children with a rare genetic disorder have higher risk of developing autism or schizophrenia, according to a UCLA Health study.
UCLA researchers have identified collagen as a key factor in kidney fibrosis, revealing its potential as a biomarker to predict chronic kidney disease progression. A repurposed anti-cancer drug, Cilengitide, was found to reduce kidney scarring and slow disease progression in preclinical models, suggesting a possible precision medicine approach for high-risk patients.
The test, called PROSTOX, is the first of its kind to use microRNAs to predict toxicity from cancer therapy. It could help prevent the burden of long-term complications by identifying patients most at risk before treatment even begins.
Home care cooperatives may be the key to alleviating the shortage of paid caregivers for older Americans. Participants in cooperatives experienced more respect, control, job support, and compensation than their counterparts in traditional care services.
A new multi-center study co-led by scientists from UCLA Health has uncovered critical genetic insights into a group of rare disorders affecting intestinal epithelial cell function, paving the way for targeted therapies that could significantly improve patient outcomes.
UCLA Health researchers have helped to develop a new digital toolbox to create a 鈥渃ommon language鈥� for brain network studies, potentially accelerating new discoveries and treatments for neurological and psychiatric conditions.
Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny chemical modification in RNA, known as m6A, plays a critical role in the progression of prostate cancer, including driving some of its most dangerous forms of the disease.
The Harrington Discovery Institute at University Hospitals and the American Society for Clinical Investigation have awarded Dr. Owen Witte(Link is external) (Link opens in new window) with the twelfth annual Harrington Prize for Innovation in Medicine.
Electronic cigarettes use may pose lower cardiovascular risks in people living with HIV compared to tobacco cigarette use, new UCLA-led research shows. The study, published in JAHA, uses a novel laboratory model to examine the early stages of atherogenesis鈥攖he buildup of fats and cholesterol in the arteries.
A new study by UCLA Health has discovered what researchers say is the first drug to fully reproduce the effects of physical stroke rehabilitation in model mice, following from human studies.
A new large-scale study provides the strongest evidence yet that a shorter, standard-dose course radiation treatment is just as effective as conventional radiotherapy for prostate cancer, without compromising the safety of patients.
A study led by UCLA investigators shows that artificial intelligence (AI) could play a key role in improving treatment outcomes for men with prostate cancer by helping physicians determine who is most likely to benefit from partial gland cryoablation, a minimally invasive procedure that treats localized prostate tumors.
Physician-scientist Theodore Scott Nowicki, MD, PhD, an assistant professor-in-residence of pediatric hematology/oncology and microbiology, immunology, & molecular genetics at the David Geffen School of Medicine at UCLA, has been awarded a $4.5 million R37 MERIT Award to help improve the effectiveness of cellular therapies for solid tumors.
A new analysis led by surgeons at UCLA Health finds that psychological prehabilitation can significantly enhance recovery after surgery. The study found that psychological prehabilitation significantly reduces the length of hospital stay, pain, anxiety, and depression after surgery.
UCLA鈥檚 Center for Advanced Surgical & Interventional Technology (CASIT) is collaborating with more than two dozen academic and industrial centers to establish a Center to Stream Healthcare in Place (C2SHIP) academic hub at UCLA
Socioeconomically disadvantaged groups may still be underusing emergency departments for potentially serious illnesses in the wake of the COVID pandemic, despite an overall rebound in emergency department use by 2022.
The prevalence of chronic conditions has risen to unprecedented levels over the past twenty years, with nearly 1-in-3, or about 25 million, young people ages 5 to 25 estimated to now be living with pediatric onset conditions that significantly affect their lives.
A new study led by UCLA investigators suggests that chronic stress and an unhealthy diet may work together to fuel the early development of pancreatic cancer, shedding light on how lifestyle factors contribute to one of the deadliest malignancies.
Scientists from UCLA, the University of Toronto and the University of Melbourne have uncovered new genetic clues that explain why some prostate cancers remain slow-growing while others become life-threatening.
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