Cancer Risk Established Before Birth
Van Andel InstituteA personâs lifetime risk for cancer may begin before they are even born, reports a paradigm-shifting study published in Nature Cancer.
A personâs lifetime risk for cancer may begin before they are even born, reports a paradigm-shifting study published in Nature Cancer.
An experimental blood test for pancreatic cancer is being evaluated by a commercial laboratory, an important milestone toward making the test available for patients.
A multi-institutional team of scientists has developed a free, publicly accessible resource to aid in classification of patient tumor samples based on distinct molecular features identified by The Cancer Genome Atlas (TCGA) Network.
An experimental blood test detects early-stage pancreatic cancer more effectively than other available tests, reports a new study published in Cancer Letters.
Scientists have developed a potent anti-cancer compound that inhibits cancer cell growth in a tough-to-treat type of infant leukemia.
Immune cells use two different routes to produce acetyl-CoA, an essential metabolite required to fight infection and cancer, reports a study led by Van Andel Institute scientists.
Humans and bakerâs yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies published in the journals Science and Proceedings of the National Academy of Sciences.
Van Andel Institute scientists have identified more than 1,000 previously undetected proteins in common metabolite samples, which persist despite extraction methods designed to weed them out.
Some proteins shift their shape when exposed to different temperatures, revealing previously unknown binding sites for medications.
A new study offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinsonâs disease and some dementias.
A pair of medications that make malignant cells act as if they have a virus could hold new promise for treating colorectal cancers and other solid tumors, reports a study published today in Science Advances.
A first-of-its-kind study has identified overactive inflammation and loss of critical protection mechanisms in the brain as potential contributors to suicide risk.
Nick Burton, Ph.D., has earned a five-year, nearly $2.9 million New Innovator Award from the National Institutes of Health Common Fund to find new ways to fix or prevent insulin resistance, a key driver of Type 2 diabetes.
Van Andel Institute Chief Scientific Officer Peter A. Jones, Ph.D., D.Sc. (hon), has received a seven-year, nearly $7.9 million grant from the National Cancer Instituteâs Outstanding Investigator Award program.
Van Andel Institute has appointed Eric Swindell, Ph.D., as dean and chief academic officer of Van Andel Institute Graduate School, effective Dec. 4, 2023.
Van Andel Institute scientists and collaborators have identified a key part of a mechanism that annotates genetic information before it is passed from fathers to their offspring.
Our cells are powered by tiny âpowerplantsâ called mitochondria, which transform nutrients into fuel that sustains life. But thereâs more to the story of mitochondria, says Van Andel Institute Assistant Professor Sara Nowinski, Ph.D.
Scientists have identified a series of processes that help the brain adapt to damage caused by breakdowns in circuits that govern movement, cognition and sensory perception.
A metabolic by-product that is more prevalent during fasting may supercharge immune cells as they fight infection and disease, reports an early stage study by Van Andel Institute scientists and collaborators.
Loss of two key âprotectorâ proteins initiates epigenetic changes that transform healthy lung cells into cancerous ones, according to new research from Van Andel Institute scientists.