Curated News: National Institutes of Health (NIH)

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13-Sep-2024 9:45 AM EDT
ESMO: Combination Therapy Reduced Agitated Delirium in Patients with Advanced Cancers
University of Texas MD Anderson Cancer Center

Treatment with a combination of haloperidol and lorazepam reduced symptoms of agitated delirium, a common end-of-life condition for patients with advanced cancers, compared with haloperidol alone, according to a new study led by researchers at The University of Texas MD Anderson Cancer Center.

Released: 12-Sep-2024 9:05 AM EDT
Triple Antibody Therapy Shows Promise for Long-Lasting HIV Control
Beth Israel Lahey Health

In a study of 12 participants, researchers at Beth Israel Deaconess Medical Center (BIDMC) have demonstrated that a cocktail of three broadly neutralizing antibodies (bNAb) successfully suppressed virus in people living with HIV. A subset of participants also demonstrated long-term control of the virus months after antibody levels declined to low or undetectable.

Newswise: UTSW study reveals how key protein affects neuron structure
Released: 11-Sep-2024 12:05 PM EDT
UTSW study reveals how key protein affects neuron structure
UT Southwestern Medical Center

A protein called torsinA plays a key role in the early development of neurons, determining where nuclear pores are placed in the membrane that encloses the nucleus of nerve cells, a study led by UT Southwestern Medical Center researchers shows.

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Released: 9-Sep-2024 1:05 PM EDT
UC Irvine Receives Record $668 Million in Research Funding for Fiscal 2023-24
University of California, Irvine

University of California, Irvine scholars, scientists and physicians continue to blaze new paths to help improve the world. In fiscal 2023-24, which ended June 30, UC Irvine received the most research funding in campus history: $668 million in grants and contracts.

Newswise: Pathway Tied to Cancer-Driving Genome Alterations Identified
Released: 9-Sep-2024 11:05 AM EDT
Pathway Tied to Cancer-Driving Genome Alterations Identified
UT Southwestern Medical Center

Cancer cells appear to hijack a genetic pathway involved in DNA repair to drive malignancy and overcome treatment, a study led by UT Southwestern Medical Center researchers shows. Their findings, published in Cell, explain how chromosomes in some tumors undergo massive rearrangements and could lead to new strategies to avoid cancer drug resistance.

Newswise: Urate Transporter Structures Reveal the Mechanism Behind Important Drug Target for Gout
Released: 9-Sep-2024 11:05 AM EDT
Urate Transporter Structures Reveal the Mechanism Behind Important Drug Target for Gout
St. Jude Children's Research Hospital

Ten structures of URAT1 obtained by scientists at St. Jude Children’s Research Hospital provide a deep understanding of the mechanism of urate transport to guide gout therapeutic design.

Newswise: One of the First of Its Kind, Uah Study Characterizes Urinary Microbes in Children
Released: 6-Sep-2024 3:05 PM EDT
One of the First of Its Kind, Uah Study Characterizes Urinary Microbes in Children
University of Alabama Huntsville

Until recently, it was believed that human urine is sterile, but advanced culturing techniques and DNA sequencing have revealed that bacteria and other microbes – such as viruses and fungi – inhabit the human bladder and urinary tract, known collectively as the “urobiome.” Now in study that is one of the first of its kind, Dr.

Released: 6-Sep-2024 12:05 PM EDT
Medical Students Explore a Future in Research Through the Summer Oncology Research Fellowship Program
Children's Hospital Los Angeles

For many students, summer break represents an opportunity for relaxation and carefree vacations. But for the medical students taking part in the USC/CHLA Summer Oncology Research Fellowship (SORF) Program, summer means something more

Released: 6-Sep-2024 11:05 AM EDT
Ulcers and Damage to Upper Gastrointestinal Tract Linked to Increased Risk of Parkinson’s Disease, Research Demonstrates
Beth Israel Lahey Health

A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) found the risk of developing Parkinson’s disease was 76 percent higher among those with a history of damage to the lining of their upper gastrointestinal (GI) tract than among those without.

Newswise: Age-Related Changes in Male Fibroblasts Increase Treatment-Resistant Melanoma
4-Sep-2024 10:00 AM EDT
Age-Related Changes in Male Fibroblasts Increase Treatment-Resistant Melanoma
Johns Hopkins Medicine

Age-related changes in the fibroblasts, cells that create the skin’s structure, contribute to the development of aggressive, treatment-resistant melanoma in males, according to research in mice by the Johns Hopkins Kimmel Cancer Center.

Released: 6-Sep-2024 10:05 AM EDT
Antibody Targeting CD38 Enzyme Shows Positive Impact in Treating Systemic Sclerosis
Michigan Medicine - University of Michigan

Scleroderma is a chronic autoimmune disease of women.Over time, people living with scleroderma develop progressive and irreversible scarring.Scarring, called fibrosis, effects the lungs, heart and kidneys, leading to poor quality of life, disability and a reduced life expectancy.

Newswise: New AI-Driven Tool Could Revolutionize Brain Pressure Monitoring in Intensive Care Patients
Released: 5-Sep-2024 10:05 AM EDT
New AI-Driven Tool Could Revolutionize Brain Pressure Monitoring in Intensive Care Patients
Mount Sinai Health System

Researchers at the Icahn School of Medicine at Mount Sinai have developed a noninvasive technique that could dramatically improve the way doctors monitor intracranial hypertension, a condition where increased pressure in the brain can lead to severe outcomes like strokes and hemorrhages.

Released: 3-Sep-2024 10:30 AM EDT
Eating Fish But Not Omega-3 Supplements During Pregnancy Associated With Lower Likelihood Of Autism Diagnosis, NIH-Funded Study Finds
Environmental influences on Child Health Outcomes NIH

Eating any amount of fish during pregnancy was associated with about a 20% lower likelihood of autism spectrum disorder (ASD) diagnosis, particularly in females, and a slight reduction in autism-related traits in offspring, according to a new study funded by the Environmental influences on Child Health Outcomes (ECHO) Program at the National Institutes of Health.

28-Aug-2024 4:05 PM EDT
Combo immunotherapy produces distinct waves of cancer-fighting T cells with each dose
Perelman School of Medicine at the University of Pennsylvania

A new tool for monitoring immune health patterns over time reveals how a pair of checkpoint inhibitor therapies works together to recruit new cancer-fighting T cells with every infusion.

Released: 29-Aug-2024 6:05 AM EDT
EVOQ Therapeutics Secures $2 Million in Funding for Advanced Autoimmune NanoDisc Therapies
EVOQ Therapeutics, Inc.

EVOQ Therapeutics, Inc. (EVOQ) a biopharmaceutical company dedicated to the treatment of autoimmune diseases, announced today the receipt of a $2 million grant from the National Institutes of Health (NIH) to advance novel therapies for autoimmune diseases.

Newswise: The latest mpox outbreak and its threat to vision
Released: 27-Aug-2024 3:30 PM EDT
The latest mpox outbreak and its threat to vision
NIH, National Eye Institute (NEI)

Monkeypox virus (mpoxv) has re-emerged, designated on August 14 as a global emergency by the World Health Organization. Newly evolved strains of mpox viruses can efficiently spread among people. In addition to skin rashes, mpox infection can cause eye complications including inflammation of the clear tissue covering the iris and pupil called the cornea (keratitis), the tissue covering the white of the eye and the underside of the eyelid (conjunctivitis, or pink eye), and the eyelid (blepharitis).

Newswise: FAMU-FSU College of Engineering research shows how insulin, zinc and pH can block harmful protein clumps linked to Type 2 diabetes
Released: 22-Aug-2024 11:05 AM EDT
FAMU-FSU College of Engineering research shows how insulin, zinc and pH can block harmful protein clumps linked to Type 2 diabetes
Florida State University

New research led by Ayyalusamy Ramamoorthy, a professor at the FAMU-FSU College of Engineering and the Florida State University-headquartered National High Magnetic Field Laboratory, shows how zinc, pH levels and insulin work together to inhibit the buildup of protein clumps that contribute to Type 2 diabetes.

   
20-Aug-2024 7:05 PM EDT
How Thyroid Hormone Fuels the Drive to Explore
Harvard Medical School

Research in mice sheds light on how thyroid hormone alters wiring in the brain. Findings reveal that thyroid hormone syncs up the brain and body to drive exploratory behavior. Researchers say their work could illuminate new treatments for certain psychiatric conditions.

16-Aug-2024 11:20 AM EDT
Researchers Aim to Pull Back the Curtain on Long COVID in Kids
Rutgers University-New Brunswick

In the most comprehensive national study since the onset of the COVID-19 pandemic, a team of researchers that includes a Rutgers-organized consortium of pediatric sites has concluded that long COVID symptoms in children are tangible, pervasive, wide ranging and clinically distinct within specific age groups.



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