Curated News: PNAS

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Newswise: Molecular Simulations, Supercomputing Lead to Energy-Saving Biomaterials Breakthrough
Released: 6-Sep-2024 1:05 PM EDT
Molecular Simulations, Supercomputing Lead to Energy-Saving Biomaterials Breakthrough
Oak Ridge National Laboratory

A team led by scientists at ORNL identified and demonstrated a method to process a plant-based material called nanocellulose that reduced energy needs by a whopping 21%, using simulations on the lab’s supercomputers and follow-on analysis.

Newswise: What microscopic fossilized shells tell us about ancient climate change
Released: 26-Aug-2024 4:05 PM EDT
What microscopic fossilized shells tell us about ancient climate change
University of Utah

By analyzing foram shells recovered in drill cores, a study led by University of Utah geologists links rapid climate change that led to thermal maxima 50 million years ago to rising CO2 levels.

Newswise: Autism Spectrum Disorders Linked to Neurotransmitter Switching in the Brain
Released: 22-Aug-2024 6:05 PM EDT
Autism Spectrum Disorders Linked to Neurotransmitter Switching in the Brain
University of California San Diego

Neurobiologists studying the emergence of autism spectrum disorders have found evidence of altered early development of the nervous system. They linked environmentally induced forms of ASD to changes in neurotransmitters, the chemical messengers that allow neurons to communicate with each other.

Newswise: Macrophage mix helps determine rate and fate of fatty liver disease
Released: 22-Aug-2024 3:05 PM EDT
Macrophage mix helps determine rate and fate of fatty liver disease
Sanford Burnham Prebys

Formerly known as nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis (MASH) is an inflammatory disease characterized by liver scarring or fibrosis that progressively impairs liver function. It is a major risk factor for cirrhosis and liver cancer. And because treatment options are limited, MASH is the second leading cause for liver transplants in the United States after cirrhosis caused by chronic hepatitis C infection. A better understanding of the pathological processes that drive MASH is critical to creating effective treatments. In a new paper published August 19, 2024 in PNAS, a team of scientists from Sanford Burnham Prebys, the University of California San Diego School of Medicine and elsewhere, describe the complex interplay between diseased liver cells and macrophages — a type of white blood cell whose jobs include killing and removing harmful cells and pathogens and helping to spur normal healing.

Newswise: Targeting protein has potential to treat leukemia, lymphoma
Released: 1-Aug-2024 10:05 AM EDT
Targeting protein has potential to treat leukemia, lymphoma
UT Southwestern Medical Center

Targeting a protein called ZFP574 suppressed leukemia in a mouse model of the disease, UT Southwestern Medical Center researchers showed in a new study. Their findings, published in PNAS (Proceedings of the National Academy of Sciences), could lead to new treatments for leukemias and lymphomas in cancer patients.

Newswise: Mini lungs make major COVID-19 discoveries possible
Released: 23-Jul-2024 2:05 PM EDT
Mini lungs make major COVID-19 discoveries possible
Sanford Burnham Prebys

Scientists at Sanford Burnham Prebys, University of California San Diego and their international collaborators have reported that more types of lung cells can be infected by SARS-CoV-2 than previously thought, including those without known viral receptors.

   
Released: 10-Jul-2024 9:05 AM EDT
Beneficial metabolic effects of PAHSAs depend on the gut microbiota in diet-induced obese mice but not in chow-fed mice
George Washington University

Dietary lipids play an essential role in regulating the function of the gut microbiota and gastrointestinal tract, and these luminal interactions contribute to mediating host metabolism. Palmitic Acid Hydroxy Stearic Acids (PAHSAs) are a family of lipids with antidiabetic and anti-inflammatory properties, but whether the gut microbiota contributes to their beneficial effects on host metabolism is unknown.

Released: 2-Jul-2024 1:05 PM EDT
Women of color disproportionately targeted by book bans, study finds
University of Colorado Boulder

The first comprehensive analysis of recent book bans in the U.S. reveals that characters and authors of color are more likely to be targeted by book bans than their white counterparts.

Newswise: Bladder buzz: technologies to improve bladder surgery and monitoring
Released: 25-Jun-2024 2:05 PM EDT
Bladder buzz: technologies to improve bladder surgery and monitoring
National Institute of Biomedical Imaging and Bioengineering

NIBIB-funded researchers are working to make bladder surgeries better, tackling the issue from two vantage points: improving bladder function using a biodegradable construct that facilitates tissue regeneration, and enhancing patient monitoring by developing an implantable bladder sensor.

Newswise: Reframing voting as ‘duty to others’ key to increasing engagement, turnout
Released: 24-Jun-2024 1:05 PM EDT
Reframing voting as ‘duty to others’ key to increasing engagement, turnout
Washington University in St. Louis

New research by Hannah Birnbaum, at Olin Business School at Washington University in St. Louis, suggests that when people view voting as a duty to others — rather than to themselves — they’re more likely to feel an obligation to vote.

Newswise: Human activity contributed to woolly rhinoceros’ extinction
Released: 3-Jun-2024 8:05 PM EDT
Human activity contributed to woolly rhinoceros’ extinction
University of Adelaide

Researchers have discovered sustained hunting by humans prevented the woolly rhinoceros from accessing favourable habitats as Earth warmed following the Last Ice Age.

Released: 3-Jun-2024 1:05 PM EDT
Stanford scientists bring crystal clarity to diamond’s quantum signals
Argonne National Laboratory

In work supported by the Q-NEXT quantum center, a Stanford University group digs into diamond to find the source of its apparently temperamental nature when it comes to emitting quantum signals, widening a path for building quantum networks and sensors.

Newswise: Detecting Odors on the Edge: Researchers Decipher How Insects Smell More with Less
Released: 21-May-2024 3:05 PM EDT
Detecting Odors on the Edge: Researchers Decipher How Insects Smell More with Less
University of California San Diego

While humans feature a sophisticated sense of smell, insects have a much more basic olfactory system. Yet they depend upon smell to survive. Scientists have figured out how fruit flies use a simple but efficient system to recognize odors, and the answer lies at the edges of their antennae.

Newswise: Long-term ocean sampling in Rhode Island's Narragansett Bay reveals plummeting plankton levels: impact uncertain for local food web
Released: 20-May-2024 3:05 PM EDT
Long-term ocean sampling in Rhode Island's Narragansett Bay reveals plummeting plankton levels: impact uncertain for local food web
University of Rhode Island

Digitizing decades worth of pre-computer files held in storage at the Narragansett Bay campus let oceanographers at the University of Rhode Island get a better picture of Narragansett Bay over time. URI operates the longest-running time series in Rhode Island, which now reveals that the level of phytoplankton in the bay has dropped by half in the last half century.

Newswise: thwaites_main-1280px-90-1060x706.jpeg
Released: 20-May-2024 3:05 PM EDT
UC Irvine-Led Team Uncovers ‘Vigorous Melting’ at Antarctica’s Thwaites Glacier
University of California, Irvine

A team of glaciologists led by researchers at the University of California, Irvine used high-resolution satellite radar data to find evidence of the intrusion of warm, high-pressure seawater many kilometers beneath the grounded ice of West Antarctica’s Thwaites Glacier.

Newswise: Tricking the Brain’s inner GPS: Grid cells responses to the illusion of self-location
Released: 20-May-2024 12:00 AM EDT
Tricking the Brain’s inner GPS: Grid cells responses to the illusion of self-location
National Research Council of Science and Technology

Dr. Hyuk-June Moon from the Bionics Research Center at the Korea Institute of Science and Technology (KIST), in collaboration with Prof. Olaf Blanke’s team at the Swiss Federal Institute of Technology Lausanne (EPFL), has successfully induced self-location illusions with multi-sensory virtual reality (VR) in the MRI scanner and observed corresponding changes in the human brain's grid cell activity.

Newswise: Bridging the gap: From frequent molecular changes to observable phenomena
Released: 15-May-2024 1:00 AM EDT
Bridging the gap: From frequent molecular changes to observable phenomena
Hokkaido University

New research employs shutter speed analogies to validate 55-year-old theory about chemical reaction rates.

Newswise: Study highlights need for cell-type-specific therapies in treatment of HIV
Released: 10-May-2024 3:05 PM EDT
Study highlights need for cell-type-specific therapies in treatment of HIV
College of Liberal Arts and Sciences, University of Illinois Urbana-Champaign

Researchers from the University of Illinois have demonstrated the importance of cell-type-specific targeting in the treatment of HIV. Their study, published in PNAS, is one of the first to examine the differential or cell-type specific effects of HIV latency modulation on myeloid cells, a type of immune cell made in bone marrow.

   
Newswise: Study led by ORNL informs climate resilience strategies in urban, rural areas
Released: 8-May-2024 11:05 AM EDT
Study led by ORNL informs climate resilience strategies in urban, rural areas
Oak Ridge National Laboratory

Local decision-makers looking for ways to reduce the impact of heat waves on their communities have a valuable new capability at their disposal: a new study on vegetation resilience.



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