Measles is a highly contagious viral infection that can cause serious health problems. The good news: Two doses of the vaccine developed in the 1960s are 97% effective in protecting you from getting infected, and that protection lasts a lifetime.
"Our ultimate goal is to develop vaccines against these very difficult viruses. Understanding how these viruses manipulate the immune response can help guide the development of the best vaccine approach."
A single vaccine could protect animal models from coronaviruses that cause COVID-19 and the flu. It works by creating antibodies that remove the virus鈥 protective sugar coat and target a rarely mutating region of the spike protein. Results will be presented at the ACS Spring 2025 Digital Meeting.
Una sola vacuna podr铆a proteger a modelos animales de los coronavirus causantes de la COVID-19 y la gripe. Esta act煤a generando anticuerpos que eliminan la capa de az煤car protectora del virus y se dirige a una regi贸n de la prote铆na Spike que rara vez muta. Los resultados se presentar谩n en el Encuentro digital de primavera de 2025 de la ACS.
Wistar Institute scientists and collaborators describe a next-generation vaccination technology that combines plasmid DNA with a lipid nanoparticle delivery system.
New study demonstrates how high-affinity B cells "bank" their best traits instead of rolling the dice and risking deleterious mutations, with implications for better vaccine design.
New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations.
Moffitt Cancer Center researchers have discovered a promising new vaccine strategy for treating a specific type of breast cancer. The innovative approach targets human epidermal growth factor receptor 2-positive, estrogen receptor-negative (HER2-positive, ER-negative) breast cancer and has shown encouraging results in a recent pilot study. Published in npj Breast Cancer, the study combined the HER2-targeting dendritic cell vaccines with standard chemotherapy, demonstrating both safety and positive response rates.
El sarampi贸n, que se cre铆a erradicado en EE.UU., est谩 reapareciendo. El n煤mero de casos de sarampi贸n en EE.UU. sigue aumentando, debido al descenso de las tasas de vacunaci贸n y a las dudas sobre la vacuna.
Measles, once thought to be eradicated in the U.S., is making a comeback. The number of U.S. measles cases continues to tick upward, caused by declining vaccination rates and vaccine hesitancy.
Chronic hepatitis B virus (HBV) infection continues to pose a major global health threat. The virus evades immune responses and antiviral therapies due to the persistence of covalently closed circular DNA (cccDNA), which serves as a viral reservoir.
Virginia Tech infectious disease epidemiologist Lisa M. Lee explains why new measles cases are being reported around the country, not just in Texas, despite the illness being declared eliminated in the U.S. in the early 2000s due to rigorous vaccine uptake. What factors have contributed to the recent measles outbreak, and why is it spreading so quickly? 鈥淢easles is back because of falling vaccination rates.
Johns Hopkins Children鈥檚 Center pediatric infectious diseases specialists Aaron Milstone, M.D., M.H.S., and Erica Prochaska, M.D., M.H.S., M.H.S., are available to discuss the following topics related to measles.