The immune system typically can ramp up the body’s defenses to clear out an invading threat without issue. Glitches can happen, however, with sepsis occurring when the mustered army of cells also attacks the body’s own tissues and organs as if they were enemy combatants.
A grant from the U.S. Department of Veterans Affairs (VA) will aid Wayne State University researchers in finding new insights into diabetes and its onset.
New research reveals how the neurovascular architecture of the murine calvarium, the skull's upper part, changes with age. Using advanced three-dimensional (3D) imaging techniques, scientists discovered significant age-related changes in the distribution and density of nerves and blood vessels in the skull. These findings offer new insights into how aging affects skeletal structure and could have implications for understanding age-related bone fragility and regenerative capacity. The study highlights the importance of neurovascular interactions in bone health, providing a foundation for future research into bone regeneration and healing.
Male and female rats with a chronic pain condition release different amounts of dopamine when given fentanyl because of sex hormones, according to a new study from WashU Medicine. The findings might help explain why men have higher rates of opioid use and overdose deaths.
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The study co-led by Dr. Elizabeth Claus of Yale Cancer Center showed an increased presence of haloalkane-associated mutational signatures in the firefighters’ tumors.
Scientists from UC San Diego have uncovered a key finding to one of water's unique properties: at high pressure and low temperature, liquid water separates into two distinct liquid phases — one high-density and one low-density.
In the JAMA Network Open study published today, Dr. Elizabeth Swisher and colleagues assessed two ways that primary-care practices could assess patients’ hereditary cancer risks and deliver testing to those identified as higher risk.
Just a few days of eating a diet high in saturated fat could be enough to cause memory problems and related brain inflammation in older adults, a new study in rats suggests.
Gut microbes shape pancreas development in infancy, leading to long-term changes in diabetes risk, new research in mice has found. The results could ultimately help doctors reduce the risk of type 1 diabetes—or potentially even restore lost pancreatic function in adulthood—with microbes that help the pancreas heal.
A team of Tufts University researchers created Morpho, an open-source programmable environment that enables researchers and engineers to conduct shape optimization and design for soft materials. Applications can be for anything from artificial hearts to robot materials that mimic flesh and soft tissue.
Scientists at St. Jude Children’s Research Hospital used positron emission tomography (PET) with edaravone, a drug used to treat ALS, to detect oxidative stress, which leads to brain damage, offering a clear path to detecting neurological conditions.
Researchers at WashU Medicine and Stanford University developed a compound that relieves pain in mice but doesn't affect the brain, thereby avoiding mind-altering side effects and abuse potential. The custom-designed molecule, derived from cannabis, may provide an alternative to opioids for treating chronic pain.
A new Penn Nursing study published in the Annals of the American Thoracic Society challenges conventional thought regarding the benefits of continuity in nursing care within intensive care units (ICUs). The researchers found that increased nurse continuity was not associated with a reduction in in-hospital mortality – in some shifts, it was even linked to a modest but statistically significant increase in mortality.
By assessing how “sticky” tumor cells are, UC San Diego researchers have found a potential way to predict whether a patient’s early-stage breast cancer is likely to spread. The discovery could help doctors identify high-risk patients and tailor their treatments accordingly.
Mount Sinai study may help early detection and treatment for glaucoma
New Study Demonstrates the Efficacy of Copper-Impregnated Surfaces in Reducing Clostridioides difficile Spores
UC San Diego engineers have developed a new computational approach to accurately model and predict the properties of a class of magnetic molecules called chiral helimagnets. Their work could accelerate the discovery of new materials for spintronics technologies.
For decades, scientists have relied on electrodes and dyes to track the electrical activity of living cells. Now, UC San Diego engineers have discovered that quantum materials just a single atom thick can do the job with high speed and resolution—using only light.
The five-year project will provide support to 4th and 5th graders in rural settings and out-of-school programs across the United States.
A new technology called PULSE (Precise Ultrasonic Liquid Sample Ejection) is set to redefine the field of single-cell research. By harnessing ultrasonic waves, PULSE offers a highly precise, automated solution for conducting experiments at the single-cell level, enabling researchers to unlock new dimensions in biological studies.
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