During every moment of any living organism’s life, enzymes are at work. These crucial proteins support life through most biological processes, including metabolism, movement, respiration, and digestion. “Enzymes’ effects in cells are part of normal physiology,” said Kathleen Mulvaney, assistant professor at Virginia Tech’s Fralin Biomedical Research Institute.
The antibody-drug conjugate (ADC) puxitatug samrotecan (AZD8205) demonstrated a manageable safety profile consistent with similar ADCs and initial efficacy in heavily pretreated patients with advanced or metastatic solid tumors, according to interim data shared today at the 2024 European Society for Medical Oncology (ESMO) Congress by researchers from The University of Texas MD Anderson Cancer Center.
A new USDA-supported project based at Iowa State University will create an encyclopedia of livestock species' genetic regulatory regions, a DNA netherworld that could be useful in breeding for improved animal efficiency and health.
A recent study highlights the pivotal role of alternative splicing in controlling plant secondary metabolism, which is crucial for producing bioactive compounds with significant medicinal and industrial value.
The Cedars-Sinai Board of Governors Regenerative Medicine Institute is creating a resource laboratory to help advance stem cell-based technologies throughout Cedars-Sinai and across California.
Mayo Clinic researchers mined the molecular foundations of cancer and uncovered a new reason chimeric antigen receptor (CAR-T cell therapy) fails in some patients. This discovery has fueled new strategies that incorporate antibodies and gene editing to improve the outcome of this breakthrough treatment for patients.
A pivotal study has decoded the genetic basis of olive oil production, revealing a key regulatory mechanism that shapes oil biosynthesis. By mapping the olive tree’s genome and metabolic pathways, researchers have identified how MYC2, a critical transcription factor, orchestrates the balance between fatty acid and flavonoid synthesis.
A recent study sheds light on Panax notoginseng, also known as Sanchi, by delving into its phytochemical profile and pharmacological potential. The research provides an in-depth review of the biosynthesis and regulation of ginsenosides, the herb's primary bioactive compounds known for their therapeutic effects.
Scientists have decoded the genetic blueprint of Atractylodes lancea, a prized herb in traditional Chinese medicine. Through comprehensive genome resequencing, the study unveils how natural variations drive the plant's evolution and metabolic adaptations, particularly affecting the production of key medicinal compounds.
Temple University’s Sbarro Institute for Cancer Research and Molecular Medicine has benefited from the support of Pennsylvania State Sen. Ryan Aument since he took office in 2014.
Researchers in ACS Central Science report a sugar-like polymer that traps heavy metals within insoluble clumps for easy removal. In proof-of-concept tests, the polymer removed ionic cadmium and lead from river water spiked with these persistent contaminants.
A recent study discovered that applying 5-Azacytidine, a DNA methylation inhibitor, significantly reduces tomato susceptibility to gray mold, a common postharvest fungal disease. This epigenetic strategy enhances the fruit's natural defense system, offering a sustainable and innovative method to boost crop resistance without genetic modification.
TORL BioTherapeutics, LLC (TORL), a clinical stage biotechnology company discovering and developing new antibody-based immunotherapies to improve and extend the lives of patients with cancer worldwide, today announced the appointment of Howard A. "Skip" Burris III, MD, FACP, FASCO as Board Member.
A recent study has uncovered how the pathogen Ralstonia solanacearum disrupts plant defenses through its type III effector RipAF1. The research shows that RipAF1 modifies a critical plant protein, FBN1, via ADP-ribosylation, which alters the plant’s hormonal signaling balance, suppressing jasmonic acid (JA) and enhancing salicylic acid (SA) pathways.
Scientists have identified a crucial gene, CsMIKC1,that controls the number of flowering sites in Cannabis sativa, a finding that could significantly enhance both medicinal and grain yields. The study reveals how CsMIKC1 drives inflorescence development, offering new pathways to boost productivity in Cannabis cultivation.
Using cutting-edge bioinformatics techniques for gene identification and sequencing, researchers at UCLA are comprehensively map signaling pathway distributions in both normal and acne-affected skin.
The Federation of American Societies for Experimental Biology (FASEB) selected nine scientists as the 2024 Howard Garrison Advocacy Fellows.
The Wake Forest Institute for Regenerative Medicine (WFIRM) is honored to announce its selection for a pioneering cancer research project that will take place aboard the International Space Station (ISS).
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right
