Newswise — LOS ANGELES (Feb. 28, 2025) -- The Cedars-Sinai  and the  set a new record in 2024 by completing 682 solid organ transplants—the most the medical center has performed in a year—as patient survival outcomes continued to meet or exceed the national average.

Cedars-Sinai is among the top 10 transplant centers in the U.S. by volume, according to published data from the Organ Procurement and Transplantation Network (OPTN), and is known for accepting complex, high-risk cases.

“Behind every transplant is a patient who desperately waited for a chance at life,” said , director of the Cedars-Sinai Comprehensive Transplant Center. “It is the remarkable generosity of organ donors and their families that allowed our transplant teams to give 682 patients the chance to have longer and healthier lives.”

Cedars-Sinai’s organ transplant program has experienced a 64% year-over-year increase since 2017, when 415 transplants were performed. Over the last decade, its transplant volume has increased by 84%, from 371 in 2014 to 682 in 2024.

Multiple drivers are behind the upward trend in organ transplants at Cedars-Sinai and nationwide, said Kim, the Esther and Mark Schulman Chair in Surgery and Transplantation Medicine.

“Machine perfusion techniques are allowing us to use donor organs that may previously have been less ideal for transplant,” Kim said. “The technology helps preserve organs before transplantation, lengthening viability, improving assessment of organ function and contributing to improved patient outcomes.”

According to the OPTN, 48,149 transplants occurred in the U.S. in 2024—more than in any other year.

But the need for more organs remains significant: More than 100,000 people in the U.S. are on the organ transplant waiting list, according to the United Network for Organ Sharing, the nonprofit organization that manages the U.S. organ transplant system.

Multiple collaborations among various sectors are underway to increase organ donations in an effort to reach a new national goal: 60,000 deceased donor transplants annually in the U.S. by the end of 2026.  

New Records in Heart, Liver and Lung Transplants

The  in the Smidt Heart Institute at Cedars-Sinai is home to the largest thoracic organ transplant program by volume in California and the second-largest heart transplant center by volume in the U.S. 

The team, including , chair of the Department of Cardiac Surgery, , surgical director of the Heart Transplant Program, and , director of the Heart Transplant Program in the Department of Cardiology, led the clinical and surgical teams that performed 137 adult heart transplants, including three heart-lung transplants, surpassing the 2023 record of 132. 

The lung transplant team, led by surgical director , and medical director , also reached a new milestone in 2024 with 88 lungs transplanted (including three heart-lung transplants), up from 82 in 2023. More than a quarter were completed using minimally invasive procedures—2- to 3-inch incisions that lead to reduced pain, recovery times and complications after surgery. Nine percent of minimally invasive lung transplant surgeries at Cedars-Sinai—more than that of any other program in the world—were robotic-assisted.

The liver transplant team, led by Kim, surgical director of the Liver Transplant Program, and , professor of Medicine and medical director of the Liver Transplant Program, performed 136 liver transplants in 2024, exceeding the 2021 record of 113 transplants.

The Kidney Transplant Program team, led by , medical director of the Comprehensive Transplant Center’s Human Leukocyte Antigen and Transplant Immunology Laboratory, and , surgical director, completed 324 transplants in 2024, including five pancreas-kidney transplants. In 2023, the program set a record with 336 kidney transplants performed.

Kim emphasized that the expertise and dedication of Cedars-Sinai’s multidisciplinary transplant teams—physicians, nurses, social workers, pharmacists, physician assistants, dietitians, technicians, perfusionists, researchers, administrative professionals and others—are what enable transplants for so many patients.

“They are the ultimate caregivers,” Kim said. “And it is the organ donors and their families who represent ultimate altruism. They are the foundation that gives others an opportunity at life.”

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