Latest news from Proceedings of the National Academy of Sciences (PNAS) on Newswise en-us Copyright 2024 Newswise 115 31 / /images/newswise-logo-rss.gif /articles/autophagy-in-pdgfr-alpha-mesenchymal-cells-is-essential-for-intestinal-nbsp-stem-cell-nbsp-survival/?sc=rsin /articles/autophagy-in-pdgfr-alpha-mesenchymal-cells-is-essential-for-intestinal-nbsp-stem-cell-nbsp-survival/?sc=rsin Fri, 13 May 2022 05:45:30 EST ... for Atg5, the stem cell loss in vivo was more pronounced than in vitro, suggesting that additional cell populations likely depend upon Atg5 function to support ileum health. We first tested whether ATG5-dependent WNT signaling was required for ... Proceedings of the National Academy of Sciences (PNAS) /articles/atr-activity-controls-nbsp-stem-cell-nbsp-quiescence-via-the-cyclin-f-ndash-scf-complex/?sc=rsin /articles/atr-activity-controls-nbsp-stem-cell-nbsp-quiescence-via-the-cyclin-f-ndash-scf-complex/?sc=rsin Mon, 02 May 2022 08:00:22 EST ... Stem cell quiescence is regulated by multiple factors including p53, Rb, cyclin-dependent kinase inhibitors, such as p21 and p27, and Notch signaling (5-10). How these pathways may integrate to maintain stem cell ... Dysregulation or loss of quiescence ... Proceedings of the National Academy of Sciences (PNAS)