display Latest news from Rockefeller University on Newswise en-us Copyright 2025 Newswise 115 31 / /images/newswise-logo-rss.gif /articles/study-implicates-60-genes-in-congenital-heart-disease-including-some-that-that-also-contribute-to-related-to-disorders-such-as-autism/?sc=rsin /articles/study-implicates-60-genes-in-congenital-heart-disease-including-some-that-that-also-contribute-to-related-to-disorders-such-as-autism/?sc=rsin Tue, 25 Mar 2025 17:40:41 EST A surprising mix of inherited and de novo mutations in 60 genes contribute to 10 percent of CHD cases. Many of these same mutations also contribute to neurodevelopmental disorders including autism.  Rockefeller University /articles/new-understanding-of-b-cell-mutation-strategies-could-have-implications-for-vaccines/?sc=rsin /articles/new-understanding-of-b-cell-mutation-strategies-could-have-implications-for-vaccines/?sc=rsin Wed, 19 Mar 2025 12:00:00 EST New study demonstrates how high-affinity B cells "bank" their best traits instead of rolling the dice and risking deleterious mutations, with implications for better vaccine design. Rockefeller University /articles/new-mechanism-behind-adaptive-immunity-revealed-it-could-impact-how-we-design-vaccines/?sc=rsin /articles/new-mechanism-behind-adaptive-immunity-revealed-it-could-impact-how-we-design-vaccines/?sc=rsin Wed, 19 Mar 2025 12:00:00 EST New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations. Rockefeller University /articles/researchers-discover-a-cause-of-leptin-resistance-and-how-to-reverse-it/?sc=rsin /articles/researchers-discover-a-cause-of-leptin-resistance-and-how-to-reverse-it/?sc=rsin Tue, 04 Mar 2025 11:00:00 EST Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss. Rockefeller University /articles/a-single-protein-may-have-helped-shape-the-emergence-of-spoken-language/?sc=rsin /articles/a-single-protein-may-have-helped-shape-the-emergence-of-spoken-language/?sc=rsin Fri, 28 Feb 2025 18:20:40 EST Rockefeller University /articles/how-solving-a-hepatitis-b-paradox-opened-the-door-to-new-therapies/?sc=rsin /articles/how-solving-a-hepatitis-b-paradox-opened-the-door-to-new-therapies/?sc=rsin Thu, 27 Feb 2025 16:50:21 EST Rockefeller University /articles/how-fruit-flies-flit-between-courtship-and-aggression-to-fight-for-mates/?sc=rsin /articles/how-fruit-flies-flit-between-courtship-and-aggression-to-fight-for-mates/?sc=rsin Thu, 13 Feb 2025 11:00:00 EST Male fruit flies don't just sing to their mates; they also use sound-cancelling wing-flicks to jockey with rivals. This new understanding of how male flies compete for female partners could shed light on how the brain balances cooperation and competition. Rockefeller University /articles/researchers-uncover-key-insights-into-how-the-body-protects-against-neuron-damage/?sc=rsin /articles/researchers-uncover-key-insights-into-how-the-body-protects-against-neuron-damage/?sc=rsin Wed, 29 Jan 2025 19:35:19 EST New research on nematodes reveals how glial cells maintain and monitor neuronal dendrites. Rockefeller University /articles/new-clues-to-the-mechanism-behind-food-tolerance-and-allergies/?sc=rsin /articles/new-clues-to-the-mechanism-behind-food-tolerance-and-allergies/?sc=rsin Tue, 28 Jan 2025 20:00:16 EST Study reveals how immune cells in the gut distinguish between food and harmful pathogens, shedding light on the origins of both food allergies and intestinal diseases. Rockefeller University /articles/unique-characteristics-of-a-rare-liver-cancer-identified-as-clinical-trial-of-new-treatment-begins/?sc=rsin /articles/unique-characteristics-of-a-rare-liver-cancer-identified-as-clinical-trial-of-new-treatment-begins/?sc=rsin Fri, 17 Jan 2025 19:00:22 EST Long classified as a subset of common liver cancer, FLC should be considered its own unique disease. Now researchers are testing a combination drug therapy that targets FLC tumors. Rockefeller University /articles/new-mechanism-for-maintaining-genome-stability-discovered/?sc=rsin /articles/new-mechanism-for-maintaining-genome-stability-discovered/?sc=rsin Tue, 14 Jan 2025 18:40:42 EST New research reveals how the RapA enzyme protects against R-loop cytotoxicity in E. coli. Rockefeller University /articles/expert-available-reduced-exposure-to-sunlight-affects-our-circadian-rhythms-and-health/?sc=rsin /articles/expert-available-reduced-exposure-to-sunlight-affects-our-circadian-rhythms-and-health/?sc=rsin Mon, 16 Dec 2024 19:25:54 EST Rockefeller University /articles/study-reveals-how-unexpected-shifts-in-cell-populations-are-revising-our-understanding-of-the-aging-process/?sc=rsin /articles/study-reveals-how-unexpected-shifts-in-cell-populations-are-revising-our-understanding-of-the-aging-process/?sc=rsin Wed, 11 Dec 2024 15:05:21 EST A newly created atlas of 21 million cells could upend long-held assumptions about how we age and provide fresh directions for anti-aging therapies. Rockefeller University /articles/the-rockefeller-university/?sc=rsin /articles/the-rockefeller-university/?sc=rsin Wed, 11 Dec 2024 11:35:56 EST Researchers discovered a vulnerability in viral enzymes that could lead to novel treatments for diseases as diverse as COVID and Ebola, while also minimizing side effects and reducing the odds of drug resistance. Rockefeller University /articles/researchers-discover-a-genetic-disposition-increasing-the-risk-of-breast-cancer-metastasis/?sc=rsin /articles/researchers-discover-a-genetic-disposition-increasing-the-risk-of-breast-cancer-metastasis/?sc=rsin Mon, 09 Dec 2024 11:00:00 EST Metastasis is responsible for 90 percent of cancer deaths. Researchers have found that the mutations driving it may stem from a commonly inherited variant of the PCSK9 gene. Rockefeller University /articles/a-new-chemistry-for-crispr/?sc=rsin /articles/a-new-chemistry-for-crispr/?sc=rsin Mon, 28 Oct 2024 12:30:10 EST It acts as a sort of molecular fumigator to battle phages and plasmids. Rockefeller University /articles/the-decision-to-eat-may-come-down-to-these-three-neurons/?sc=rsin /articles/the-decision-to-eat-may-come-down-to-these-three-neurons/?sc=rsin Wed, 23 Oct 2024 14:15:10 EST Manipulating a newly identified neural circuit can curb appetite--or spur massive overeating. Rockefeller University /articles/surprising-reason-that-b-cells-benefit-from-booster-shots/?sc=rsin /articles/surprising-reason-that-b-cells-benefit-from-booster-shots/?sc=rsin Wed, 23 Oct 2024 12:55:03 EST Certain infectious diseases, such as COVID or the flu, evolve constantly, shapeshifting just enough to outmaneuver our immune systems and reinfect us repeatedly. But subsequent reinfections often don't lead to the most severe outcomes--for very good reason. Upon first exposure to a pathogen, our immune systems churn out specially trained B cells, which have learned to identify and eliminate the virus. Rockefeller University /articles/west-nile-infections-are-spiking-here-s-why-the-percentage-of-severe-cases-is-so-small/?sc=rsin /articles/west-nile-infections-are-spiking-here-s-why-the-percentage-of-severe-cases-is-so-small/?sc=rsin Wed, 23 Oct 2024 12:45:09 EST The U.S. is currently in the midst of yet another West Nile virus (WNV) outbreak, with the CDC documenting 880 cases across 46 states so far this year. Rockefeller University /articles/in-studying-the-mating-rituals-of-fruit-flies-scientists-may-have-learned-something-about-how-brains-evolve/?sc=rsin /articles/in-studying-the-mating-rituals-of-fruit-flies-scientists-may-have-learned-something-about-how-brains-evolve/?sc=rsin Wed, 09 Oct 2024 15:05:03 EST Researchers have identified how the architecture of brain circuits helps different species flexibly adapt to new mating signals across evolutionary timeframes. Rockefeller University