Latest news from Cell Reports on Newswise en-us Copyright 2024 Newswise 115 31 / /images/newswise-logo-rss.gif /articles/ptbp1-promotes-hematopoietic-nbsp-stem-cell-nbsp-maintenance-and-red-blood-cell-development-by-ensuring-sufficient-availability-of-ribosomal-constituents/?sc=rsin /articles/ptbp1-promotes-hematopoietic-nbsp-stem-cell-nbsp-maintenance-and-red-blood-cell-development-by-ensuring-sufficient-availability-of-ribosomal-constituents/?sc=rsin Mon, 16 May 2022 05:45:38 EST ... Given the important function of PTBP1 in directing lineage choice in diverse stem cell systems and the overall relevance of mRNA splicing in hematopoiesis, we hypothesized that PTBP1 might play a role as a regulator of posttranscriptional ... Cell Reports /articles/escargot-controls-somatic-nbsp-stem-cell-nbsp-maintenance-through-the-attenuation-of-the-insulin-receptor-pathway-in-drosophila/?sc=rsin /articles/escargot-controls-somatic-nbsp-stem-cell-nbsp-maintenance-through-the-attenuation-of-the-insulin-receptor-pathway-in-drosophila/?sc=rsin Mon, 25 Apr 2022 02:10:00 EST ... a decline in nutrient availability is likely to provide insight into the metabolic regulation of stem cell behavior in other tissues and organisms. ... Taken together, our data describe one mechanism by which a transcription factor controls stem cell ... Cell Reports /articles/autologous-nk-cells-as-consolidation-therapy-following-nbsp-stem-cell-nbsp-transplantation-in-multiple-myeloma/?sc=rsin /articles/autologous-nk-cells-as-consolidation-therapy-following-nbsp-stem-cell-nbsp-transplantation-in-multiple-myeloma/?sc=rsin Mon, 21 Feb 2022 07:00:43 EST Few approaches have been made toward exploring autologous NK cells in settings of cancer immunotherapy. Here, we demonstrate the feasibility of infusing multiple doses of ex vivo activated and expanded autologous NK cells in patients with ... Cell Reports /articles/soxd-genes-are-required-for-adult-neural-nbsp-stem-cell-nbsp-activation/?sc=rsin /articles/soxd-genes-are-required-for-adult-neural-nbsp-stem-cell-nbsp-activation/?sc=rsin Mon, 07 Feb 2022 03:00:35 EST The adult neurogenic niche in the hippocampus is maintained through activation of reversibly quiescent neural stem cells (NSCs) with radial glia-like morphology (RGLs). Here, we show that the expression of SoxD transcription factors Sox5 and Sox6 is ... Cell Reports /articles/single-cell-atac-seq-of-fetal-human-retina-and-nbsp-stem-cell-derived-retinal-organoids-shows-changing-chromatin-landscapes-during-cell-fate-acquisition/?sc=rsin /articles/single-cell-atac-seq-of-fetal-human-retina-and-nbsp-stem-cell-derived-retinal-organoids-shows-changing-chromatin-landscapes-during-cell-fate-acquisition/?sc=rsin Tue, 01 Feb 2022 01:00:36 EST ... We performed scATAC-seq on human fetal retina and human embryonic stem cell (hESC)-derived retinal organoids (Table S1), including 7 fetal retinas (2 that were cultured for 4 days in vitro [DIV]) and 5 organoid samples containing approximately ... Cell Reports /articles/coordinate-control-of-basal-epithelial-cell-fate-and-nbsp-stem-cell-nbsp-maintenance-by-core-emt-transcription-factor-zeb1/?sc=rsin /articles/coordinate-control-of-basal-epithelial-cell-fate-and-nbsp-stem-cell-nbsp-maintenance-by-core-emt-transcription-factor-zeb1/?sc=rsin Fri, 14 Jan 2022 08:55:40 EST ... , but the molecular mechanisms that coordinately control basal cell fate and stem cell quiescence are elusive. Here, we report an epithelium-... stem cell function to Zeb1-deficient basal cells. Thus, Zeb1 is a transcriptional regulator that maintains ... Cell Reports