Latest news from Endocrinology on Newswise en-us Copyright 2024 Newswise 115 31 / /images/newswise-logo-rss.gif /articles/cyp11a2-is-essential-for-oocyte-development-and-spermatogonial-nbsp-stem-cell-nbsp-differentiation-in-zebrafish/?sc=rsin /articles/cyp11a2-is-essential-for-oocyte-development-and-spermatogonial-nbsp-stem-cell-nbsp-differentiation-in-zebrafish/?sc=rsin Mon, 27 Dec 2021 03:00:12 EST Cytochrome P45011A1, encoded by Cyp11a1, converts cholesterol to pregnenolone (P5), the first and rate-limiting step in steroidogenesis. In zebrafish, cyp11a1 is maternally expressed and cyp11a2 is considered the ortholog of Cyp11a1 in ... Endocrinology