Latest news from Laboratory Investigation on Newswise en-us Copyright 2024 Newswise 115 31 / /images/newswise-logo-rss.gif /articles/a-murine-mesenchymal-nbsp-stem-cell-nbsp-model-for-initiating-events-in-osteosarcomagenesis-points-to-cdk4-cdk6-inhibition-as-a-therapeutic-target/?sc=rsin /articles/a-murine-mesenchymal-nbsp-stem-cell-nbsp-model-for-initiating-events-in-osteosarcomagenesis-points-to-cdk4-cdk6-inhibition-as-a-therapeutic-target/?sc=rsin Tue, 21 Dec 2021 02:00:39 EST Osteosarcoma is a high-grade bone-forming neoplasm, with a complex genome. Tumours frequently show chromothripsis, many deletions, translocations and copy number alterations. Alterations in the p53 or Rb pathway are the most common ... Laboratory Investigation