Latest news from World Journal of Stem Cells on Newswise en-us Copyright 2024 Newswise 115 31 / /images/newswise-logo-rss.gif /articles/understanding-and-controlling-the-variables-for-stromal-vascular-fraction-therapy/?sc=rsin /articles/understanding-and-controlling-the-variables-for-stromal-vascular-fraction-therapy/?sc=rsin Mon, 26 Aug 2024 12:00:58 EST In regenerative medicine, the isolation of mesenchymal stromal cells (MSCs) from the adipose tissue's stromal vascular fraction (SVF) is a critical area of study. Our review meticulously examines the isolation process of MSCs, starting wi World Journal of Stem Cells /articles/bone-marrow-mesenchymal-stem-cells-in-treatment-of-peripheral-nerve-injury/?sc=rsin /articles/bone-marrow-mesenchymal-stem-cells-in-treatment-of-peripheral-nerve-injury/?sc=rsin Mon, 26 Aug 2024 12:00:56 EST Peripheral nerve injury (PNI) is a common neurological disorder and complete functional recovery is difficult to achieve. In recent years, bone marrow mesenchymal stem cells (BMSCs) have emerged as ideal seed cells for PNI treatment due to World Journal of Stem Cells /articles/pretreatment-can-alleviate-programmed-cell-death-in-mesenchymal-stem-cells/?sc=rsin /articles/pretreatment-can-alleviate-programmed-cell-death-in-mesenchymal-stem-cells/?sc=rsin Mon, 26 Aug 2024 12:00:52 EST In this editorial, we delved into the article titled "Cellular preconditioning and mesenchymal stem cell ferroptosis." This groundbreaking study underscores a pivotal discovery: Ferroptosis, a type of programmed cell death, drastically World Journal of Stem Cells /articles/understanding-and-controlling-the-variables-for-advanced-cell-therapy/?sc=rsin /articles/understanding-and-controlling-the-variables-for-advanced-cell-therapy/?sc=rsin Mon, 26 Aug 2024 12:00:51 EST In regenerative medicine, the isolation of mesenchymal stromal cells (MSCs) from the adipose tissue's stromal vascular fraction (SVF) is a critical area of study. Our review meticulously examines the isolation process of MSCs, starting wi World Journal of Stem Cells /articles/potential-plausible-role-of-wharton-s-jelly-mesenchymal-stem-cells-for-diabetic-bone-regeneration/?sc=rsin /articles/potential-plausible-role-of-wharton-s-jelly-mesenchymal-stem-cells-for-diabetic-bone-regeneration/?sc=rsin Mon, 26 Aug 2024 12:00:47 EST This letter addresses the review titled "Wharton's jelly mesenchymal stem cells: Future regenerative medicine for clinical applications in mitigation of radiation injury". The review highlights the regenerative potential of Wharton' World Journal of Stem Cells /articles/mesenchymal-stem-cells-a-promising-therapeutic-avenue-for-non-alcoholic-fatty-liver-disease/?sc=rsin /articles/mesenchymal-stem-cells-a-promising-therapeutic-avenue-for-non-alcoholic-fatty-liver-disease/?sc=rsin Mon, 26 Aug 2024 12:00:46 EST Non-alcoholic fatty liver disease (NAFLD) is a pressing global health concern that is associated with metabolic syndrome and obesity. On the basis of the insights provided by Jiang et al, this editorial presents an exploration of the potent World Journal of Stem Cells /articles/microvesicles-derived-from-mesenchymal-stem-cells-inhibit-acute-respiratory-distress-syndrome-related-pulmonary-fibrosis-in-mouse-partly-through-hepatocyte-growth-factor/?sc=rsin /articles/microvesicles-derived-from-mesenchymal-stem-cells-inhibit-acute-respiratory-distress-syndrome-related-pulmonary-fibrosis-in-mouse-partly-through-hepatocyte-growth-factor/?sc=rsin Mon, 26 Aug 2024 12:00:10 EST BACKGROUNDPulmonary fibrosis is one of the main reasons for the high mortality rate among acute respiratory distress syndrome (ARDS) patients. Mesenchymal stromal cell-derived microvesicles (MSC-MVs) have been shown to exert antifibrotic ef World Journal of Stem Cells /articles/additional-comments-on-extracellular-vesicles-derived-from-mesenchymal-stem-cells-mediate-extracellular-matrix-remodeling-in-osteoarthritis/?sc=rsin /articles/additional-comments-on-extracellular-vesicles-derived-from-mesenchymal-stem-cells-mediate-extracellular-matrix-remodeling-in-osteoarthritis/?sc=rsin Fri, 26 Jul 2024 12:00:48 EST Recently, we read an article published by the Yang et al. The results of this study indicated that engineered exosomes loaded with microRNA-29a (miR-29a) alleviate knee inflammation and maintain extracellular matrix stability in Sprague Daw World Journal of Stem Cells /articles/wharton-s-jelly-mesenchymal-stem-cells-future-regenerative-medicine-for-clinical-applications-in-mitigation-of-radiation-injury/?sc=rsin /articles/wharton-s-jelly-mesenchymal-stem-cells-future-regenerative-medicine-for-clinical-applications-in-mitigation-of-radiation-injury/?sc=rsin Fri, 26 Jul 2024 12:00:23 EST Wharton's jelly mesenchymal stem cells (WJ-MSCs) are gaining significant attention in regenerative medicine for their potential to treat degenerative diseases and mitigate radiation injuries. WJ-MSCs are more naive and have a better safe World Journal of Stem Cells /articles/current-perspectives-on-mesenchymal-stem-cells-as-a-potential-therapeutic-strategy-for-non-alcoholic-fatty-liver-disease/?sc=rsin /articles/current-perspectives-on-mesenchymal-stem-cells-as-a-potential-therapeutic-strategy-for-non-alcoholic-fatty-liver-disease/?sc=rsin Fri, 26 Jul 2024 12:00:23 EST Non-alcoholic fatty liver disease (NAFLD) has emerged as a significant health challenge, characterized by its widespread prevalence, intricate natural progression and multifaceted pathogenesis. Although NAFLD initially presents as benign fa World Journal of Stem Cells /articles/priming-mesenchymal-stem-cells-to-develop-super-stem-cells/?sc=rsin /articles/priming-mesenchymal-stem-cells-to-develop-super-stem-cells/?sc=rsin Wed, 26 Jun 2024 12:00:57 EST The stem cell pre-treatment approaches at cellular and sub-cellular levels encompass physical manipulation of stem cells to growth factor treatment, genetic manipulation, and chemical and pharmacological treatment, each strategy having adva World Journal of Stem Cells /articles/umbilical-cord-mesenchymal-stem-cell-exosomes-alleviate-necrotizing-enterocolitis-in-neonatal-mice-by-regulating-intestinal-epithelial-cells-autophagy/?sc=rsin /articles/umbilical-cord-mesenchymal-stem-cell-exosomes-alleviate-necrotizing-enterocolitis-in-neonatal-mice-by-regulating-intestinal-epithelial-cells-autophagy/?sc=rsin Wed, 26 Jun 2024 12:00:51 EST BACKGROUNDNecrotizing enterocolitis (NEC) is a severe gastrointestinal disease that affects premature infants. Although mounting evidence supports the therapeutic effect of exosomes on NEC, the underlying mechanisms remain unclear. AIMTo i World Journal of Stem Cells /articles/priming-mesenchymal-stem-cells-to-develop-super-stem-cells2/?sc=rsin /articles/priming-mesenchymal-stem-cells-to-develop-super-stem-cells2/?sc=rsin Wed, 26 Jun 2024 12:00:46 EST The stem cell pre-treatment approaches at cellular and sub-cellular levels encompass physical manipulation of stem cells to growth factor treatment, genetic manipulation, and chemical and pharmacological treatment, each strategy having adva World Journal of Stem Cells /articles/gut-microbiota-modulating-intestinal-stem-cell-differentiation/?sc=rsin /articles/gut-microbiota-modulating-intestinal-stem-cell-differentiation/?sc=rsin Wed, 26 Jun 2024 12:00:42 EST Proliferation and differentiation of intestinal stem cell (ISC) to replace damaged gut mucosal epithelial cells in inflammatory states is a critical step in ameliorating gut inflammation. However, when this disordered proliferation continue World Journal of Stem Cells /articles/priming-mesenchymal-stem-cells-to-develop-super-stem-cells4/?sc=rsin /articles/priming-mesenchymal-stem-cells-to-develop-super-stem-cells4/?sc=rsin Wed, 26 Jun 2024 12:00:35 EST The stem cell pre-treatment approaches at cellular and sub-cellular levels encompass physical manipulation of stem cells to growth factor treatment, genetic manipulation, and chemical and pharmacological treatment, each strategy having adva World Journal of Stem Cells /articles/mesenchymal-stem-cells-extracellular-vesicles-alleviate-pulmonary-fibrosis-by-regulating-immunomodulators/?sc=rsin /articles/mesenchymal-stem-cells-extracellular-vesicles-alleviate-pulmonary-fibrosis-by-regulating-immunomodulators/?sc=rsin Wed, 26 Jun 2024 12:00:30 EST BACKGROUNDPulmonary fibrosis (PF) is a chronic interstitial lung disease characterized by fibroblast proliferation and extracellular matrix formation, causing structural damage and lung failure. Stem cell therapy and mesenchymal stem cells- World Journal of Stem Cells /articles/outcomes-of-combined-mitochondria-and-mesenchymal-stem-cells-derived-exosome-therapy-in-rat-acute-respiratory-distress-syndrome-and-sepsis/?sc=rsin /articles/outcomes-of-combined-mitochondria-and-mesenchymal-stem-cells-derived-exosome-therapy-in-rat-acute-respiratory-distress-syndrome-and-sepsis/?sc=rsin Wed, 26 Jun 2024 12:00:29 EST BACKGROUNDThe treatment of acute respiratory distress syndrome (ARDS) complicated by sepsis syndrome (SS) remains challenging. AIMTo investigate whether combined adipose-derived mesenchymal-stem-cells (ADMSCs)-derived exosome (EXAD) and ex World Journal of Stem Cells /articles/safety-and-efficiency-of-wharton-s-jelly-derived-mesenchymal-stem-cell-administration-in-patients-with-traumatic-brain-injury-first-results-of-a-phase-i-study/?sc=rsin /articles/safety-and-efficiency-of-wharton-s-jelly-derived-mesenchymal-stem-cell-administration-in-patients-with-traumatic-brain-injury-first-results-of-a-phase-i-study/?sc=rsin Wed, 26 Jun 2024 12:00:26 EST BACKGROUNDTraumatic brain injury (TBI) is characterized by a disruption in the normal function of the brain due to an injury following a trauma, which can potentially cause severe physical, cognitive, and emotional impairment. Stem cell tra World Journal of Stem Cells /articles/exosomes-from-umbilical-cord-mesenchymal-stromal-cells-promote-the-collagen-production-of-fibroblasts-from-pelvic-organ-prolapse/?sc=rsin /articles/exosomes-from-umbilical-cord-mesenchymal-stromal-cells-promote-the-collagen-production-of-fibroblasts-from-pelvic-organ-prolapse/?sc=rsin Wed, 26 Jun 2024 12:00:26 EST BACKGROUNDPelvic organ prolapse (POP) involves pelvic organ herniation into the vagina due to pelvic floor tissue laxity, and vaginal structure is an essential factor. In POP, the vaginal walls exhibit abnormal collagen distribution and dec World Journal of Stem Cells /articles/rplp0-tbp-are-the-most-stable-reference-genes-for-human-dental-pulp-stem-cells-under-osteogenic-differentiation/?sc=rsin /articles/rplp0-tbp-are-the-most-stable-reference-genes-for-human-dental-pulp-stem-cells-under-osteogenic-differentiation/?sc=rsin Wed, 26 Jun 2024 12:00:24 EST BACKGROUNDValidation of the reference gene (RG) stability during experimental analyses is essential for correct quantitative real-time polymerase chain reaction (RT-qPCR) data normalisation. Commonly, in an unreliable way, several studies u World Journal of Stem Cells