Latest news from Stem Cell Research on Newswise en-us Copyright 2024 Newswise 115 31 / /images/newswise-logo-rss.gif /articles/measurement-of-activity-of-developmental-signal-transduction-pathways-to-quantify-nbsp-stem-cell-nbsp-pluripotency-and-phenotypically-characterize-differentiated-cells/?sc=rsin /articles/measurement-of-activity-of-developmental-signal-transduction-pathways-to-quantify-nbsp-stem-cell-nbsp-pluripotency-and-phenotypically-characterize-differentiated-cells/?sc=rsin Mon, 21 Mar 2022 06:00:26 EST Stem Cell Research /articles/cancer-nbsp-stem-cell-nbsp-markers-for-liver-cancer-and-pancreatic-cancer/?sc=rsin /articles/cancer-nbsp-stem-cell-nbsp-markers-for-liver-cancer-and-pancreatic-cancer/?sc=rsin Tue, 08 Feb 2022 11:00:41 EST ... This study will be helpful to understand cancer stem cell like cells. ... of cancer stem cells are very difficult, mainly due to the lack of specific cancer stem cell markers. ... Until now, we don't know which subgroup cells in cancer are cancer ... Stem Cell Research /articles/generation-of-hipsc-line-umi030-a-from-an-individual-with-the-hearing-loss-related-gjb2-mutation-c-109g-a/?sc=rsin /articles/generation-of-hipsc-line-umi030-a-from-an-individual-with-the-hearing-loss-related-gjb2-mutation-c-109g-a/?sc=rsin Fri, 17 Dec 2021 08:00:49 EST Genetic variants in the GJB2 gene which encodes for the Connexin 26 protein account for ∼ 60% of cases of genetic hearing loss. A novel hiPSC line was generated from an individual with the hearing loss-related variant c.109G > A in GJB2 lead Stem Cell Research /articles/generation-of-crispr-cas9-edited-human-induced-pluripotent-stem-cell-line-carrying-flnc-exon-skipping-variant/?sc=rsin /articles/generation-of-crispr-cas9-edited-human-induced-pluripotent-stem-cell-line-carrying-flnc-exon-skipping-variant/?sc=rsin Fri, 17 Dec 2021 08:00:42 EST *FLNC hiPSC line useable for cardiomyocytes differenciation and heart tissu production.*Isogenic pair of iPSc generated through CRISPR/Cas9 Non-Homologous End Joining.*Homozygous Exon skipping FLNC human iPSc model for cardiomyopathy.*Decreas Stem Cell Research /articles/generation-of-induced-pluripotent-stem-cell-line-zzui015-a-from-a-dm1-patient-with-cataract/?sc=rsin /articles/generation-of-induced-pluripotent-stem-cell-line-zzui015-a-from-a-dm1-patient-with-cataract/?sc=rsin Fri, 17 Dec 2021 08:00:37 EST Myotonic dystrophy (DM1) is mainly caused by abnormal number of the CTG repeat sequence of the DMPK gene. DM1 clinically manifests mainly as progressive muscular atrophy and muscle weakness. Cataracts form in the eyes of some patients. We successfull Stem Cell Research /articles/atm-modulates-subventricular-zone-neural-stem-cell-maintenance-and-senescence-through-notch-signaling-pathway/?sc=rsin /articles/atm-modulates-subventricular-zone-neural-stem-cell-maintenance-and-senescence-through-notch-signaling-pathway/?sc=rsin Fri, 17 Dec 2021 08:00:32 EST *DNA damage accumulation increased in ATM deficient neural progenitor cells.*ATM is essential for maintaining the stemness of adult NSCs.*ATM deficiency accelerates NSC senescence.*Whole-genome transcriptomic analysis unravels Notch signaling Stem Cell Research /articles/establishment-of-a-patient-specific-induced-pluripotent-stem-cell-line-dhmi004-a-from-a-male-holt-oram-syndrome-patient-with-verified-tbx5-mutation/?sc=rsin /articles/establishment-of-a-patient-specific-induced-pluripotent-stem-cell-line-dhmi004-a-from-a-male-holt-oram-syndrome-patient-with-verified-tbx5-mutation/?sc=rsin Fri, 17 Dec 2021 08:00:11 EST The Holt-Oram syndrome (HOS) is a rare autosomal dominant disorder, mostly based on mutations in the TBX5 gene. Patients show malformation of at least one upper limb along with congenital heart defects. The established induced pluripotent stem cell ( Stem Cell Research