Newswise Feature Channel: Cancer

Data Detectives Strike Back at Deadly Childhood Cancer

University of South Australia — Sun, 10 Nov 2024 14:30:59 EST

Neuroblastoma is a rare and aggressive form of childhood cancer. Striking in infancy, it shatters what should be a family's time of joy, shifting it to a fight for survival. While the search for a cure continues, researchers at the University of South Australia are striving to decode the causes of neuroblastoma to inform new, less toxic treatment strategies for young patients.

Cohesin RAD21 Gene Promoter Methylation in Patients with Acute Myeloid Leukemia

National Center For Scientific Research Demokritos — Fri, 08 Nov 2024 13:15:06 EST

PIM-1L Kinase Binds to and Inactivates SRPK1: A Biochemical and Molecular Dynamics Study

National Center For Scientific Research Demokritos — Fri, 08 Nov 2024 13:05:19 EST

SR/RS dipeptide repeats vary in both length and position, and are phosphorylated by SR protein kinases (SRPKs). PIM-1L, the long isoform of PIM-1 kinase, the splicing of which has been implicated in acute myeloid leukemia, contains a domain that consists largely of repeating SR/RS and SH/HS dipeptides (SR/SH-rich).

MD Anderson launches Institute for Cell Therapy Discovery & Innovation to deliver transformational new therapies

University of Texas MD Anderson Cancer Center — Fri, 08 Nov 2024 12:00:57 EST

The University of Texas MD Anderson Cancer Center today announced the launch of its Institute for Cell Therapy Discovery & Innovation, which will build upon longstanding MD Anderson clinical and research expertise to lead the world in developing and advancing impactful cell therapies for patients in need.

Cleveland Clinic Announces Updated Findings in Preventive Breast Cancer Vaccine Study

Cleveland Clinic — Fri, 08 Nov 2024 10:25:35 EST

Cleveland Clinic researchers are presenting updated findings from their novel study of a vaccine aimed at preventing triple-negative breast cancer, the most aggressive and lethal form of the disease. The study team found that the investigational vaccine was generally well tolerated and produced an immune response in most patients. The team described the side effects of the vaccine, showed the highest tolerated dose to date, and presented the immunologic effects of the vaccine. Findings are being presented at the Society for Immunotherapy of Cancer Annual Meeting.

Tip Sheet: A Gene Drive to Treat Herpes, Improving Clinical Trials for Immunocompromised People -- and Breast Sexual Health Clinic Opens

Fred Hutchinson Cancer Center — Fri, 08 Nov 2024 09:00:15 EST

Below are summaries of recent Fred Hutch Cancer Center research findings, patient stories and other news.

أوصى باحثو مايو كلينك ببدائل لاستئصال الرحم لعلاج الأورام الليفية في الرحم، وفقًا لدراسة

Mayo Clinic — Thu, 07 Nov 2024 16:05:48 EST

روتشستر، مينيسوتا -- تُعد الأورام الليفية الرحمية حالة شائعة تؤثر على ما يصل إلى 80٪ من النساء خلال حياتهن. سيعاني ما يقرب من نصف هؤلاء النساء من أعراض تؤثر على جودة حياتهن وقدرتهن على الإنجاب، بما في ذلك الألم الشديد وفقر الدم. تُعد الأورام الليفية الرحمية السبب الرئيسي لإجراء استئصال الرحم. ومع ذلك، يوصي باحثو مايو كلينك ببدائل علاجية طفيفة التوغل لاستئصال الرحم، وذلك وفقًا لورقة عمل سريرية دُعيت للنشر في مجلة نيو إنجلاند الطبية.

Pesquisadores da Mayo Clinic recomendam alternativas a histerectomia para miomas uterinos, de acordo com estudo

Mayo Clinic — Thu, 07 Nov 2024 14:50:08 EST

Os miomas uterinos sao uma condicao comum que afeta ate 80% das mulheres ao longo da vida. Quase metade dessas mulheres apresentara sintomas que afetarao sua qualidade de vida e fertilidade, incluindo dor intensa e anemia. Os miomas uterinos sao a principal razao para se realizar a remocao do utero atraves da histerectomia. No entanto, pesquisadores da Mayo Clinic recomendam alternativas de tratamento minimamente invasivas a histerectomia em um artigo convidado sobre pratica clinica publicado na New England Journal of Medicine.

Researchers Make Glioblastoma Cells Visible to Attacking Immune Cells

Washington University in St. Louis — Thu, 07 Nov 2024 13:15:09 EST

Researchers at WashU Medicine have identified a possible way to make glioblastoma cells vulnerable to different types of immunotherapy. The strategy, which they demonstrated in cells in the lab, forces brain cancer cells to display targets for the immune system to attack. Their study was published in Nature Genetics.

Hematology, Oncology, Neuro-Oncology & Stem Cell Transplantation Updates: Fall 2024

Ann and Robert H. Lurie Children's Hospital of Chicago — Thu, 07 Nov 2024 12:00:13 EST

Lurie Children's is proud to announce the appointment of new leadership across key programs and sections within the Center for Cancer and Blood Disorders.

Researchers Find Metabolic Mechanism That Blocks Immune Response, Immunotherapy in Cancer

Michigan Medicine - University of Michigan — Thu, 07 Nov 2024 11:50:30 EST

Researchers at the University of Michigan Rogel Cancer Center have discovered a key reason why some cancers do not respond to immunotherapy: A metabolite transporter within the tumor microenvironment that blocks a key type of tumor cell death integral to immune response.

Cancer Genetic Risk Assessment Guidelines Expand to Meet Growing Understanding of Hereditary Risk

National Comprehensive Cancer Network(r) (NCCN(r)) — Thu, 07 Nov 2024 08:30:00 EST

NCCN expands guidelines to create two major resources for helping cancer care providers and other stakeholders stay current on cutting edge research on genetic/familial high-risk assessment.

Brown Foundation Award for Excellence in Oncology Nursing honors Tiffany Richards

University of Texas MD Anderson Cancer Center — Wed, 06 Nov 2024 17:50:11 EST

The University of Texas MD Anderson Cancer Center today honored Tiffany Richards, Ph.D., A.P.R.N., A.N.P.-B.C., A.O.C.N.P., with the 2024 Brown Foundation Award for Excellence in Oncology Nursing.

MSK Research Highlights, November 6, 2024

Memorial Sloan Kettering Cancer Center — Wed, 06 Nov 2024 11:35:15 EST

New MSK research marks a potential advance against RAS-driven cancers; breaks down data silos to better predict cancer outcomes with the help of artificial intelligence (AI); identifies two enzymes vital for maintaining brain health; uncovers how changes to "helper" proteins drive cancer cell survival; develops a new model for investigating lung cancer metastasis; and uses AI to improve outcome predictions in sarcoma.

Deteccion de indicios de cancer de pulmon en el aliento exhalado

American Chemical Society (ACS) — Wed, 06 Nov 2024 09:10:29 EST

En un estudio publicado en la revista ACS Sensors, investigadores informan del desarrollo de sensores ultrasensibles a nanoescala que, en pruebas a pequena escala, distinguen un cambio clave en la quimica del aliento de personas con cancer de pulmon.

Detecting Evidence of Lung Cancer in Exhaled Breath

American Chemical Society (ACS) — Wed, 06 Nov 2024 08:00:00 EST

Exhaled breath contains chemical clues to what's going on inside the body, including diseases like lung cancer. And devising ways to sense these compounds could help doctors provide early diagnoses -- and improve patients' prospects. In a study in ACS Sensors, researchers report developing ultrasensitive, nanoscale sensors that in small-scale tests distinguished a key change in the chemistry of the breath of people with lung cancer. November is Lung Cancer Awareness Month.

Ancient Immune Defense System Plays an Unexpected Role in Cancer, MSK Researchers Find

Memorial Sloan Kettering Cancer Center — Tue, 05 Nov 2024 14:10:23 EST

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in unexpected ways -- ways that have important implications for the development of cancer, researchers at MSK are discovering.

SLU Study: Integrative Palliative Care Critical to Improve Mental Health Among Pancreatic Cancer Patients

Saint Louis University — Tue, 05 Nov 2024 13:40:30 EST

For patients facing a pancreatic cancer diagnosis, a compassionate approach to care can be transformative. Yet, a new study published in Healthcare reveals that palliative care, a service focused on enhancing the quality of life for those with serious illnesses, remains significantly underutilized among pancreatic cancer patients in the United States.

Chili Peppers Exhibit Antitumor Effect on Mesothelioma Cancer Cells

Sbarro Health Research Organization (SHRO) — Tue, 05 Nov 2024 12:55:04 EST

Capsaicin, the compound in chili peppers which gives them their spicy taste, may become a source of new, natural drugs for the hard-to-treat Mesothelioma type of cancer.

How Hypoxia Helps Cancer Spread

Johns Hopkins Medicine — Tue, 05 Nov 2024 11:30:21 EST

Scientists at the Johns Hopkins Kimmel Cancer Center have identified 16 genes that breast cancer cells use to survive in the bloodstream after they've escaped the low-oxygen regions of a tumor. Each is a potential therapeutic target to stop cancer recurrence, and one - MUC1 - is already in clinical trials.