Newswise Feature Channel: Regenerative Medicine

Making Heart Scar Tissue a Nonissue

Sanford Burnham Prebys — Fri, 07 Mar 2025 19:05:21 EST

New Sanford Burnham Prebys scientist Ahmed Mahmoud, PhD, and his team focus on how to repair adult hearts by restoring the regenerative powers they once possessed early in development. He wants to advance the discoveries he has made in regenerating hearts in mice to develop treatments that may one day benefit patients.

Bio-Inspired Electronics: Soft, Biohybrid, and "Living" Neural Interfaces

Perelman School of Medicine at the University of Pennsylvania — Fri, 28 Feb 2025 17:40:17 EST

Supramolecular Polymers: The Future of Biomedical and Engineering Solutions

Chinese Academy of Sciences — Fri, 28 Feb 2025 07:15:40 EST

A new study has unveiled the potential of hydrogen-bonding crosslinked supramolecular polymer materials derived from N-acryloyl glycinamide (NAGA). These innovative materials exhibit exceptional mechanical strength, self-healing properties, and tunable functionalities, positioning them as versatile solutions for industries ranging from biomedical engineering to flexible electronics and energy storage.

Study Sheds Light on Liver Maturation, Specialization

College of Liberal Arts and Sciences, University of Illinois Urbana-Champaign — Mon, 03 Feb 2025 20:25:31 EST

Researchers from the University of Illinois have identified a key process coordinating liver maturation and polyploidization, a state in which cells carry more than two sets of chromosomes. Their findings provide insight into hepatocyte specialization that will aid efforts in regenerative medicine.

Daniel B.F. Saris, MD, PhD, Receives the First Arnold I. Caplan Award for Distinguished Research in Orthobiologics

American Academy of Orthopaedic Surgeons (AAOS) — Thu, 30 Jan 2025 11:00:36 EST

The American Academy of Orthopaedic Surgeons (AAOS) announced Daniel B. F. Saris, MD, PhD, as the inaugural recipient of the Arnold I. Caplan Award for Distinguished Research in Orthobiologics (Caplan Award).

Stromal Vascular Fraction: Mechanisms and Application in Reproductive Disorders

World Journal of Stem Cells — Sun, 26 Jan 2025 12:00:04 EST

Stromal vascular fraction (SVF) is a complex mixture derived from adipose tissue, consisting of a variety of cells. Due to its potential for tissue repair, immunomodulation, and support of angiogenesis, SVF represents a promising frontier i

ARVO Foundation names 2024 Point of View Award winner

Association for Research in Vision and Ophthalmology (ARVO) — Fri, 24 Jan 2025 09:30:55 EST

Rockville, Md.--The ARVO Foundation congratulates Mohajeet Bhuckory, PhD (Stanford University) -- the 2024 recipient of the Point of View Award. Established by the Point of View Foundation (Fundacio Punt de Vista), the award provides a $20,000 cash prize in recognition of an outstanding scholarly article related to efforts to restore vision through regenerative ophthalmology, biotechnology, whole eye transplantation or other approaches.

Unlocking the Potential of Skin Organoids for Hair Follicle Development

Chinese Academy of Sciences — Wed, 22 Jan 2025 08:35:21 EST

A pioneering study has unveiled the transformative role of air-liquid interface (ALI) culture in the morphogenesis of hair follicles within skin organoids derived from human-induced pluripotent stem cells (hiPSCs).

DDR2: The Key to Unlocking Bone Regeneration and Treating Heterotopic Ossification

Chinese Academy of Sciences — Fri, 17 Jan 2025 08:45:30 EST

Bone regeneration research has taken a significant leap forward with the discovery of a crucial mechanism that could transform treatments for bone disorders. Scientists have identified how Discoidin Domain Receptor 2 (DDR2) enhances Bone Morphogenetic Protein (BMP)-dependent bone regeneration while mitigating the risk of heterotopic ossification (HO), offering promising therapeutic opportunities. This breakthrough sheds light on how DDR2 regulates BMP activity, paving the way for safer and more effective interventions in bone repair and related conditions.

UC Irvine-led Discovery of New Skeletal Tissue Advances Regenerative Medicine Potential

University of California, Irvine — Thu, 09 Jan 2025 21:30:08 EST

IAn international research team led by the University of California, Irvine has discovered a new type of skeletal tissue that offers great potential for advancing regenerative medicine and tissue engineering.

The Wake Forest Institute for Regenerative Medicine Joins Project to Make Vision-Restoring Whole Eye Transplants a Reality

Wake Forest Institute for Regenerative Medicine — Tue, 07 Jan 2025 18:50:00 EST

The Wake Forest Institute for Regenerative Medicine (WFIRM) is part of a major undertaking that will bring together more than 40 scientists, doctors, and industry experts from around the country to make vision-restoring whole eye transplants a reality. The award of up to $56 million is from the Advanced Research Projects Agency for Health (ARPA-H) Transplantation of Human Eye Allografts (THEA) program.

Engineering a Smile

National Institute of Biomedical Imaging and Bioengineering — Mon, 23 Dec 2024 18:05:42 EST

NIH-funded researchers restore facial nerve function in animals with stem cell-based conduits

Cedars-Sinai, UCSF Experts Steer the Development of Stem Cells to Regenerate and Repair Organs

Cedars-Sinai — Thu, 19 Dec 2024 21:00:34 EST

Investigators from Cedars-Sinai and the University of California, San Francisco (UCSF) have identified a new way to deliver instructions that tell stem cells to grow into specific bodily structures, a critical step in eventually regenerating and repairing tissues and organs.

Two Case Western Reserve University faculty members honored as Fellows of the National Academy of Inventors

Case Western Reserve University — Tue, 10 Dec 2024 10:00:00 EST

Polymer scientist Gary E. Wnek and stem-cell biologist Arnold Caplan have been named Fellows of the National Academy of Inventors (NAI), the highest professional distinction awarded solely to inventors.

New Gene Therapy Reverses Heart Failure in Large Animal Model

University of Utah Health — Tue, 10 Dec 2024 05:00:00 EST

With one IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves survival.

NSF-Piedmont Triad Regenerative Medicine Engine (PTRME) Awards $2.5 Million in Grants to Drive Economic Growth

Wake Forest Institute for Regenerative Medicine — Wed, 04 Dec 2024 14:30:16 EST

The Piedmont Triad Regenerative Medicine Engine (PTRME), funded by the National Science Foundation (NSF), has announced a groundbreaking investment of $2.5 million in the region's regenerative medicine industry through its inaugural Ecosystem Building Grant program. This milestone underscores PTRME's leadership in regenerative medicine and commitment to positioning the Piedmont Triad as a global hub for innovation. Six innovative companies have been awarded grants to support the commercialization of regenerative medicine products. This funding is expected to catalyze technological advancements, strengthen the local economy, and drive the region's competitiveness on a global scale.

American University to Welcome Recent Graduate Sean Astin, SPA/MPAP '24, as Commencement Speaker for Fall Commencement

American University — Mon, 02 Dec 2024 14:40:00 EST

Noted actor and American University graduate Sean Astin will address the Class of 2024

Refining Adipose-Derived Stem Cell Isolation for Optimal Regenerative Therapy

World Journal of Stem Cells — Tue, 26 Nov 2024 12:00:42 EST

This article highlights the importance of optimizing the techniques used for isolating stromal vascular fraction cells from adipose tissue. Furthermore, by presenting key findings from the literature, it clarifies the effects of refined tec

Squishy Microgels in Granular Biomaterials Confine and Direct Cell Behavior

Penn State Materials Research Institute — Tue, 26 Nov 2024 09:45:31 EST

A simple biomaterial-based strategy that can influence the behavior of cells could pave the way for more effective medical treatments such as wound healing, cancer therapy and even organ regeneration, according to a research team at Penn State.

Novel Gene Therapy Trial for Sickle Cell Disease Launches

University of California, San Francisco (UCSF) — Tue, 26 Nov 2024 07:30:39 EST

UCSF Benioff Children's Hospital Oakland is enrolling patients in an innovative clinical trial that seeks to cure sickle cell disease. The trial is the first in the U.S. to apply non-viral CRISPR-Cas9 gene-editing technology in humans to directly correct the genetic mutation that causes the disease.