Newswise Feature Channel: Transplantation

Using Stem-Cell Transplants to Treat Blindness

Universite de Montreal — Tue, 10 Dec 2024 12:00:24 EST

UdeM scientists have developed a method to create retinal transplants from stem cells, and with them, blind mini-pigs have showed signs of restored vision, a promising development for humans, as well.

New Targets for Diabetic Kidney Disease Could Prevent End Stage Kidney Failure

University of Bristol — Tue, 10 Dec 2024 06:25:28 EST

New potential therapeutic targets have been identified for diabetic kidney disease (DKD) - the leading cause of kidney failure in the world - that could see patients treated with new gene and drug therapies preventing the disease's progression into end stage kidney failure.

ASH: Triplet combination regimens demonstrate high response rates in multiple leukemias

University of Texas MD Anderson Cancer Center — Mon, 09 Dec 2024 20:00:38 EST

Three clinical trials led by researchers from The University of Texas MD Anderson Cancer Center demonstrated significant positive results from novel triplet therapies in the treatment of relapsed or refractory and newly diagnosed leukemias. The results were presented at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition. More information on all ASH Annual Meeting content from MD Anderson can be found at MDAnderson.org/ASH.

Multi-Center Study Shows Education Level, Income Impact Access to Stem Cell Transplantation for Acute Myeloid Leukemia Patients

Fred Hutchinson Cancer Center — Sun, 08 Dec 2024 11:10:31 EST

Patients with acute myeloid leukemia who have lower education levels and lower income are less likely to receive a allogeneic hematopoietic stem cell transplant for acute myeloid, however, if they can access the treatment, are equally likely to benefit from transplant as patients with more education and higher income, according to a new study from Fred Hutch Cancer Center presented at the annual meeting of the American Society of Hematology.

3D BioLabs Achieves Pivotal Milestone in Development of 3D Printed Liver Implant

3D BioLabs — Thu, 05 Dec 2024 15:35:56 EST

3D BioLabs LLC ("3D BioLabs" or "3DB"), has reached a pivotal milestone in the field of regenerative medicine as recently published in the Proceedings of the National Academy of Sciences. 3DB's study has demonstrated a new approach to creating large organs to solve the organ transplant shortage.

New Drug Tested to Reduce Side Effect of 'Half-Matched' Stem Cell Transplants

Washington University in St. Louis — Thu, 05 Dec 2024 14:35:41 EST

Stem cell transplantation is used to treat several types of blood cancers, but carries the risk of a life-threatening side effect called graft-versus-host disease. Results from a clinical trial conducted by researchers at WashU Medicine showed adding the investigational drug itacitinib to standard care for "half-matched" stem cell transplantation may reduce rates of the disease, in which the donor's stem cells attack the patient's healthy tissues.

U-M Rogel Cancer Center Names 2 New Clinical Research Leaders

Michigan Medicine - University of Michigan — Thu, 05 Dec 2024 13:30:43 EST

The University of Michigan Rogel Cancer Center has named Kyle Cuneo, M.D., its new associate director for clinical research. In addition, a new position of assistant director for clinical research will be filled by John Magenau, M.D.

NSF-Piedmont Triad Regenerative Medicine Engine (PTRME) Awards $2.5 Million in Grants to Drive Economic Growth

Wake Forest Institute for Regenerative Medicine — Wed, 04 Dec 2024 14:30:16 EST

The Piedmont Triad Regenerative Medicine Engine (PTRME), funded by the National Science Foundation (NSF), has announced a groundbreaking investment of $2.5 million in the region's regenerative medicine industry through its inaugural Ecosystem Building Grant program. This milestone underscores PTRME's leadership in regenerative medicine and commitment to positioning the Piedmont Triad as a global hub for innovation. Six innovative companies have been awarded grants to support the commercialization of regenerative medicine products. This funding is expected to catalyze technological advancements, strengthen the local economy, and drive the region's competitiveness on a global scale.

American Society of Nephrology Celebrates New Legislation to Expand Support for Living Donors

American Society of Nephrology (ASN) — Wed, 04 Dec 2024 14:20:29 EST

The American Society of Nephrology (ASN) celebrates the introduction of the Expanding Support for Living Donors Act of 2024, legislation that would bolster and expand support for living organ donors.

Bascom Palmer Receives Multimillion Dollar Award to Support Functional Whole-Eye Transplant

University of Miami Health System, Miller School of Medicine — Tue, 03 Dec 2024 15:25:48 EST

Researchers with Bascom Palmer Eye Institute are tackling the formidable task of surgically recovering a live human eye and maintaining its function for vision restoration through organ transplantation.

Fred Hutch at ASH: Plenary Session on Socioeconomic Barriers to Transplant, New Leukemia Treatments and Phasing Out 'Cumbersome' Urine Test

Fred Hutchinson Cancer Center — Tue, 03 Dec 2024 14:45:18 EST

The of the American Society of Hematology (ASH) will take place in San Diego, Calif. and online Dec. 7-10. Improving access to life-saving therapies for blood disorders is the theme of many presentations by Fred Hutch Cancer Center experts, including: Meta-analyses show socioeconomic factors limit access to transplants and clinical trials, highlighting strategies to overcome barriers.

UTSW Joins Project to Make Whole Eye Transplants a Reality

UT Southwestern Medical Center — Tue, 03 Dec 2024 12:50:44 EST

UT Southwestern Medical Center is part of a major undertaking that will bring together more than 40 scientists, doctors, and industry experts handpicked from around the country to make vision-restoring whole eye transplants a reality.

American Society of Nephrology Welcomes New CMMI Model Aimed at Boosting Transplant Rates

American Society of Nephrology (ASN) — Wed, 27 Nov 2024 10:10:02 EST

The American Society of Nephrology (ASN) welcomes the final Increasing Organ Transplant Access (IOTA) model rule from the Centers for Medicare and Medicaid Innovation (CMMI).

Melatonin-Based Priming of Stem Cells to Alleviate Oxidative Stress

World Journal of Stem Cells — Tue, 26 Nov 2024 12:00:35 EST

Stem cell expansion in vitro and transplantation in the cytokine-rich proinflammatory milieu in the injured tissue generate immense oxidative stress that interferes with the cells' survival, stemness, and repairability. Stem cell priming

Perfect Match: Woman Donates Lifesaving Kidney to Her Identical Twin

Cedars-Sinai — Tue, 26 Nov 2024 11:40:04 EST

Identical twins Linda Thomas and Karen Rodman, 56, have shared everything from the moment they were born. The Las Vegas residents live less than five miles from each other. They work together, carpool together, shop together. Their phone numbers would be identical, save for the last digit.

Special De-Liver-Y Transplant: Aunt Donates Portion of Liver to Save Young Adult Niece

UT Southwestern Medical Center — Thu, 21 Nov 2024 16:35:26 EST

Anyone watching Kelly Rowe set records as a sprinter at Mansfield Lake Ridge High School and then compete on a track scholarship at the University of Mississippi, would assume she was in peak health. They'd have no reason to suspect she had been on a battery of medications and gone to countless doctor appointments ever since she was 8. That's when she was diagnosed with autoimmune hepatitis, a condition that attacks the liver and leads to long-term damage.

UChicago Medicine Expands in Hinsdale with New Salt Creek Clinic

University of Chicago Medical Center — Wed, 20 Nov 2024 14:00:24 EST

UChicago Medicine's current clinic on Salt Creek Lane in Hinsdale will close Nov. 21, and open across the street in a new, larger facility Dec. 2.

مايو كلينك تجري عملية زرع وجه بنجاح، وتستعيد وظيفة الوجه

Mayo Clinic — Tue, 19 Nov 2024 08:25:10 EST

أصبح رجل قادرًا على الرمش والبلع والابتسام والتنفس من خلال أنفه لأول مرة منذ عقد من الزمان، وذلك بفضل عملية زرع وجه أجريت في مايو كلينك. يسلط هذا الإجراء التحويلي والمعقد الضوء على مهارة الفريق الجراحي متعدد التخصصات في مايو كلينك، والذي يقدم الأمل للمرضى الذين يعانون من احتياجات طبية معقدة.

Mayo Clinic realiza transplante facial com sucesso, restaurando as funcoes vitais

Mayo Clinic — Tue, 19 Nov 2024 08:20:30 EST

Um homem pode piscar, engolir, sorrir e respirar pelo nariz pela primeira vez em uma decada, gracas a um transplante facial realizado na Mayo Clinic. Esse procedimento complexo e transformador destaca a equipe cirurgica multidisciplinar altamente capacitada da Mayo Clinic, que oferece esperanca aos pacientes com necessidades medicas complexas.

Mayo Clinic realiza un trasplante facial exitoso, restaurando las funciones vitales

Mayo Clinic — Tue, 19 Nov 2024 08:15:37 EST

Un hombre puede parpadear, tragar, sonreir y respirar por la nariz por primera vez en una decada, gracias a un trasplante facial realizado en Mayo Clinic. Este procedimiento complejo y transformador destaca al equipo quirurgico multidisciplinario altamente capacitado de Mayo Clinic, que ofrece esperanza a los pacientes con necesidades medicas complejas.