Newswise Feature Channel: Healthspan

Researchers Discover a Cause of Leptin Resistance--and How to Reverse It

Rockefeller University — Tue, 04 Mar 2025 11:00:00 EST

Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss.

Mount Sinai Researchers Identify Molecular Glues That Protect Insulin-Producing Cells From Damage Related to Diabetes

Mount Sinai Health System — Tue, 04 Mar 2025 10:00:06 EST

Findings could improve long-term outcomes for patients

AI Meets Mental Health: Wi-Fi-Based Depression Detection for Aging Populations

JMIR Publications — Tue, 04 Mar 2025 09:45:20 EST

A new study published in JMIR Aging developed and tested an innovative artificial intelligence (AI) model called HOPE that uses Wi-Fi-based motion sensor data to detect depression in older adults.

Special Type of Fat Tissue Could Promote Healthful Longevity and Help Maintain Exercise Capacity in Aging

Rutgers University-New Brunswick — Tue, 04 Mar 2025 09:40:54 EST

The discovery by Rutgers Health researchers suggests a potential new approach to improving fitness in older adults.

Rutgers Names Director of Center for Pharmacoepidemiology and Treatment Science at Institute for Health

Rutgers University-New Brunswick — Tue, 04 Mar 2025 09:10:00 EST

Vincent Lo Re, an internationally recognized pharmacoepidemiology researcher, has been named director of the Center for Pharmacoepidemiology and Treatment Science (PETS), a unit of the Rutgers Institute for Health, Health Care Policy and Aging Research (IFH).

Iron Overload: Accelerator of Deadly Cell Responses in Stroke

Chinese Academy of Sciences — Tue, 04 Mar 2025 08:45:21 EST

A pivotal study has uncovered that iron orchestrates the activation of two damaging cell death pathways--ferroptosis and necroptosis--early in ischemic stroke recovery, exacerbating brain injury. This discovery sheds light on how iron disruption fuels neurological damage, positioning iron regulation as a promising therapeutic target to protect the brain during the critical reperfusion phase.

STIM1: The Cancer Shield Against Sorafenib Unmasked

Chinese Academy of Sciences — Tue, 04 Mar 2025 08:20:58 EST

A recent study unveils how stromal interaction molecule 1 (STIM1), a protein involved in calcium signaling, plays a pivotal role in the resistance of liver cancer to sorafenib, a key treatment for advanced hepatocellular carcinoma (HCC).

Mapping the Genetic Landscape of Alzheimer's Brain Regions

Chinese Academy of Sciences — Tue, 04 Mar 2025 06:10:46 EST

A new study uncovers crucial insights into the gene interactions linked to Alzheimer's disease (AD), revealing how amyloid-beta accumulation affects gene dynamics across different brain regions and age groups. Using spatial transcriptomics (ST), researchers show how specific genes like Ttr and Trem2 behave differently depending on disease progression and age. These findings offer a new lens for understanding AD at the molecular level, with the potential to inform targeted therapies and interventions aimed at slowing or halting the disease's progression.

Decoding Bone Health: Single-Cell Insights Into Type 2 Diabetes

Chinese Academy of Sciences — Tue, 04 Mar 2025 05:20:33 EST

A pioneering study offers unprecedented insights into the bone immune microenvironment of type 2 diabetic mice, uncovering a unique genetic profile that includes decreased osteoclast differentiation.

Study Uncovers Genetic Drivers of Aggressive Prostate Cancer

University of California, Los Angeles (UCLA), Health Sciences — Mon, 03 Mar 2025 20:25:31 EST

Scientists from UCLA, the University of Toronto and the University of Melbourne have uncovered new genetic clues that explain why some prostate cancers remain slow-growing while others become life-threatening.

Osteoporosis Screening with Opportunistic CT Could Double Screening Rates and Avoid up to 2.5 Billion in Medical Costs

Harvey L. Neiman Health Policy Institute — Mon, 03 Mar 2025 19:40:08 EST

A new multi-institute study demonstrates the potential prevention and economic benefits from the opportunistic use of CT (OCT), defined as screening performed using CT images that were collected for a different purpose. The study, published in the Journal of the American College of Radiology, showed that using CT imaging that includes the upper lumbar spine in its field of view to screen for osteoporosis could increase the screening rate in the Medicare fee-for-service population by 113% without requiring any additional imaging. The work was a collaboration among researchers from the Harvey L. Neiman Health Policy Institute, New York University Langone Health, and Massachusetts General Hospital.

Researchers Debunk Common Belief That Women Get Better Muscles by Timing Their Workouts to Their Menstrual Cycles

McMaster University — Mon, 03 Mar 2025 17:45:58 EST

New research from kinesiologists at McMaster University is challenging the internet belief that timing resistance training to specific phases of the menstrual cycle boosts the body's ability to build muscle and strength.

New Federal Mandate on Breast Density: Experts Provide Essential Guidance for Clinicians and Patients

University of California, Los Angeles (UCLA), Health Sciences — Mon, 03 Mar 2025 17:35:03 EST

To help guide informed discussions between physicians and patients, Dr. Elmore and Christoph Lee, MD, MS, from the University of Washington School of Medicine, outline six key questions, published in JAMA.

UC San Diego Innovators to Spotlight Transformative Science at SXSW 2025

University of California San Diego — Mon, 03 Mar 2025 12:00:53 EST

The SXSW Conference will take place from March 7-15 in Austin, Texas, bringing together a vibrant mix of ideas and innovations. Once again, UC San Diego will take center stage, showcasing cutting-edge research, transformative discussions on critical global challenges and a film premiere.

Cleveland Clinic Develops Prediction Score to Estimate Risk of Early-Onset Colorectal Cancer and Precancerous Polyps

Cleveland Clinic — Mon, 03 Mar 2025 08:30:51 EST

Cleveland Clinic researchers developed and validated a prediction model that estimates the risk of developing colorectal cancer and advanced precancerous polyps in adults under 45 years old. The paper was published in Digestive Diseases and Sciences

Wistar Scientists Discover a Promising Brain Cancer Target

Wistar Institute — Fri, 28 Feb 2025 18:35:09 EST

Filippo Veglia, Ph.D., and lab have discovered the process of how brain tumors reprogram certain immune cells called neutrophils from cancer enemies to cancer allies.

Funding the Future of Health: Investment Lessons from GLP-1s

Hevolution Foundation — Fri, 28 Feb 2025 18:15:24 EST

The Future of Longevity: Why Prevention Needs a New Business Model

Hevolution Foundation — Fri, 28 Feb 2025 18:10:50 EST

Are GLP-1s the First True Longevity Drug?

Hevolution Foundation — Fri, 28 Feb 2025 18:10:12 EST

Colorectal Cancer on the Rise in Younger Adults: One Woman's Journey during Pregnancy

Hackensack Meridian Health — Thu, 27 Feb 2025 10:50:55 EST

Colorectal cancer incidence rates continue to rise in those under age 50 -- a trend that underscores the need for increased awareness and early detection. During this Colorectal Cancer Awareness Month, experts from Hackensack Meridian Health are available to discuss this trend, along with a patient diagnosed with CRC at age 37 while pregnant.