Newswise Feature Channel: Digestive Disorders

Gut Microorganism May Play a Role in Constipation

Cedars-Sinai — Thu, 29 Aug 2024 11:05:53 EST

A new Cedars-Sinai study shows how microorganisms in the human gut can trigger constipation in some people.

CHLA Gastroenterologist Provides Guidance on the Use of Intestinal Ultrasound in Inflammatory Bowel Disease Care for New Clinical Practice Update

Children's Hospital Los Angeles — Thu, 29 Aug 2024 11:05:32 EST

Mallory Chavannes, MD, MHSc, FRCPC, FAAP, Clinical Director of the Inflammatory Bowel Disease Program at Children's Hospital Los Angeles, has co-written "AGA Clinical Practice Update on the Role of Intestinal Ultrasound in Inflammatory Bowel Disease: Commentary," a new clinical practice update from the American Gastroenterological Association (AGA) Institute.

EUS-RV and precut sphincterotomy equally effective salvage techniques to treat benign biliary obstructions and can serve as a backup for each other

American College of Physicians (ACP) — Mon, 26 Aug 2024 17:00:00 EST

A randomized control trial compared endoscopic ultrasound-guided rendezvous technique (EUS-RV) and precut sphincterotomy as salvage techniques for difficult bile duct cannulation in benign biliary obstruction.

ACG/ASGE Release Updated Quality Indicators for Colonoscopy

American College of Gastroenterology (ACG) — Thu, 22 Aug 2024 09:00:13 EST

ACG and ASGE have issued recommendations on quality indicators for colonoscopy, the gold standard for colorectal cancer screening (CRC).

Gut bioelectricity provides a path for bad bacteria to cause diseases

UC Davis Health — Wed, 21 Aug 2024 21:05:15 EST

UC Davis Health researchers has discovered a novel bioelectrical mechanism pathogens like Salmonella use to find entry points in the gut lining that would allow them to pass and cause infection.

MD Anderson Research Highlights for August 21, 2024

University of Texas MD Anderson Cancer Center — Wed, 21 Aug 2024 12:00:44 EST

UTHealth Houston researchers launch $3.3M study on how eating patterns and circadian rhythms impact aging

University of Texas Health Science Center at Houston — Mon, 19 Aug 2024 12:05:02 EST

Inflammatory Bowel Disease Televisits, Added RSV Risks, and More in the August Issue of AJG

American College of Gastroenterology (ACG) — Mon, 19 Aug 2024 08:05:06 EST

The August issue of AJG includes articles on IBD, including the use of telehealth and added risks for RSV hospitalization, and the updated nomenclature for metabolic dysfunction-associated steatotic liver disease (MASLD).

3D body volume scanner uses AI to help predict metabolic syndrome risk

Mayo Clinic — Thu, 15 Aug 2024 15:05:47 EST

Mayo Clinic researchers are using artificial intelligence (AI) with an advanced 3D body-volume scanner - originally developed for the clothing industry - to help doctors predict metabolic syndrome risk and severity.

"You Can Be Both," A Single Mom's Journey to Becoming a Renowned Telomere Scientist

University of North Carolina School of Medicine — Thu, 15 Aug 2024 14:05:35 EST

Taghreed Mohammed Al-Turki, PhD, a postdoctoral researcher in the UNC Lineberger lab of Jack Griffith, PhD, describes her long, difficult, and rewarding journey of becoming a telomere scientist as a first-time mother at the University of North Carolina School of Medicine.

Novel Test Helps ID Patients at High Risk of Esophageal Cancers

Johns Hopkins Medicine — Thu, 15 Aug 2024 13:05:07 EST

A novel test developed by Johns Hopkins Kimmel Cancer Center investigators could give gastroenterologists insight into which patients with Barrett's esophagus -- a premalignant condition in which parts of the esophagus become damaged by chronic acid reflux -- are likely to progress to esophageal cancer or an abnormal collection of cells called high-grade dysplasia.

Removing Bile Acid Receptor in Gut Blocks Intestinal Inflammation

American Physiological Society (APS) — Thu, 15 Aug 2024 08:05:14 EST

Removing a nuclear bile acid receptor that regulates glucose and lipid stability from the intestine blocked gut inflammation in mice, according to researchers at Children's Hospital Los Angeles.

Cleveland Clinic study reveals diet as main risk factor for colon cancer in younger adults

Cleveland Clinic — Wed, 14 Aug 2024 15:05:35 EST

A new Cleveland Clinic study has identified diet-derived molecules called metabolites as main drivers of young-onset colorectal cancer risk, especially those associated with red and processed meat. The NPJ Precision Oncology report, which analyzed metabolite and microbiome datasets, highlighted that one of the best ways a younger (<60 years) adult can prevent colorectal cancer is to discuss their diet with their doctor.

Study by Cleveland Clinic, Tufts University Highlights Potential for Using TMAO -- a Digestive By-Product -- to Predict Heart Failure Risk

Cleveland Clinic — Wed, 14 Aug 2024 09:05:21 EST

New Cleveland Clinic and Tufts University research shows that elevated levels of the gut microbiome trimethylamine N-oxide (TMAO) pathway led to a higher risk of heart failure independent of other risk factors, according to a study of two large National Institutes of Health cohorts. The study was recently published in the journal Circulation: Heart Failure.

Joslin Diabetes Center Investigator Rohit N. Kulkarni, MD, PhD, Awarded $10 Million NIH/NIDDK Grant for Pioneering Diabetes and Obesity Research

Beth Israel Lahey Health — Mon, 12 Aug 2024 10:05:30 EST

Rohit N. Kulkarni, MD, PhD, the Diabetes Research and Wellness Foundation Endowed Chair and Co-Head of the Section on Islet & Regenerative Biology at Joslin Diabetes Center, has been awarded $9,920,607 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health (NIH).

Botanical medicine reduces rectal cancer treatment side effects that can sideline surgeries

Yale Cancer Center/Smilow Cancer Hospital — Fri, 09 Aug 2024 17:05:04 EST

Ancient Chinese traditional medicine significantly reduces the side effects of rectal cancer treatments that, in some patients, can be so toxic that treatment must be paused, or stopped, which diminishes its effectiveness.

Study identifies weight-loss drug target in the brain

UT Southwestern Medical Center — Thu, 08 Aug 2024 10:05:10 EST

A team led by researchers from UT Southwestern Medical Center and a university in South Korea has identified a subset of brain cells whose activation may be partially responsible for the effects of a popular class of weight loss drugs that includes semaglutide and tirzepatide. Their findings, published in Science, could eventually help scientists optimize the efficacy of these drugs, known as glucagon-like peptide-1 receptor agonists (GLP-1RAs).

MD Anderson Research Highlights for August 7, 2024

University of Texas MD Anderson Cancer Center — Wed, 07 Aug 2024 12:00:40 EST

The University of Texas MD Anderson Cancer Center's Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson's world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments at MD Anderson include insights into evolutionary cellular adaptations to environmental stressors, potential targets to overcome trouble swallowing in head and neck cancer patients treated with radiation therapy, a promising chemotherapy-free combination treatment for patients with a subset of acute lymphocytic leukemia, a single-cell atlas for stomach cancer metastasis, encouraging results of a PARP inhibitor on patients with advanced cancers and specific DNA damage repair mutations, and a liquid biopsy signature that could improve early pancreatic cancer detection.

Johns Hopkins Medicine Scientists Probe Molecular Cause of COVID-19 Related Diarrhea, Revealing Potential Treatments

Johns Hopkins Medicine — Tue, 06 Aug 2024 11:00:02 EST

Working with human stem cells that form a kind of "mini intestine-in-a-dish," Johns Hopkins Medicine scientists say they have found several molecular mechanisms for COVID-19-related diarrhea, suggesting potential ways to control it.

Diarreia do viajante: Especialista fornece dicas para evitar este desvio desagradavel em sua viagem

Mayo Clinic — Thu, 01 Aug 2024 15:05:41 EST

A diarreia do viajante e um disturbio comum e desconfortavel do trato digestivo que pode afetar as pessoas quando elas viajam para novos lugares. Ela e causada pela ingestao de alimentos ou agua contaminados. O Dr.Jesse Bracamonte, medico de familia na Mayo Clinic em Phoenix, diz que a diarreia do viajante nao e geralmente grave, mas pode ser altamente desagradavel.