Newswise Feature Channel: Digestive Disorders

Interplay and Therapeutic Implications of Colorectal Cancer Stem Cells, Tumor Microenvironment, and Gut Microbiota

World Journal of Stem Cells — Thu, 26 Dec 2024 12:00:54 EST

This article discusses the interplay between colorectal cancer (CRC) stem cells, tumor microenvironment (TME), and gut microbiota, emphasizing their dynamic roles in cancer progression and treatment resistance. It highlights the adaptabilit

TNF Inhibitors Prevent Complications in Kids with Crohn's Disease, Recommended as First-Line Therapies

Michigan Medicine - University of Michigan — Mon, 23 Dec 2024 17:50:50 EST

Early treatment of pediatric Crohn's disease with anti-tumor necrosis factor medications can substantially reduce the risk of perianal fistulas, a particularly debilitating complication of Crohn's disease. Michigan Medicine researchers confirmed this finding using prospective data.

Potential Culprit Identified in Lingering Crohn's Disease Symptoms

Michigan Medicine - University of Michigan — Fri, 20 Dec 2024 17:50:07 EST

A study from University of Michigan researchers may provide an explanation for why some patients with Crohn's disease continue to experience symptoms, even in the absence of inflammation.

Dry January and Beyond, Why Experts Say It May Be The Best Way To Drink To Your Health

Hackensack Meridian Health — Thu, 19 Dec 2024 10:20:11 EST

Experts Available On The Worrying Research On Alcohol

The Surprising Role of Gut Infection in Alzheimer's Disease

Arizona State University (ASU) — Thu, 19 Dec 2024 07:00:00 EST

ASU- and Banner Alzheimer's Institute-led study implicates link between a common virus and the disease, which travels from the gut to the brain and may be a target for antiviral treatments

Researchers Identify Key Driver of Fibrosis in Crohn's Disease

University of North Carolina School of Medicine — Wed, 18 Dec 2024 18:55:36 EST

Researchers at the UNC School of Medicine have found a key process by which gut bacteria may be contributing to intestinal fibrosis, a major complication of an intestinal inflammatory disease called Crohn's disease.

Risk Factors for Inadequate Bowel Preparation and More in the December Issue of The American Journal of Gastroenterology

American College of Gastroenterology (ACG) — Tue, 17 Dec 2024 21:20:31 EST

The December issue of AJG highlights new clinical science and reviews, including outcomes among transgender adults with cirrhosis, risk factors for inadequate bowel preparation, and upadacitinib versus tofacitinib in ulcerative colitis. This month also includes articles on celiac disease, belching disorders, eosinophilic esophagitis, pancreatitis, and more.

UW Researchers Find Previously Unknown Links Between Microbial Bile Acids and the Risk of Colon Cancer

University of Wisconsin-Madison — Mon, 16 Dec 2024 19:05:24 EST

Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats. It turns out that two of these microbially-modified bile acids may affect our risk -- in opposite directions -- for developing colon cancer.

β-Ionone Shows Promise in Preventing Ulcerative Colitis Through Gut Barrier Protection and Microbiota Regulation

Chinese Academy of Sciences — Fri, 13 Dec 2024 17:00:49 EST

A research team reveals that β-ionone, a naturally occurring compound with known anti-inflammatory and antimicrobial properties, may offer a novel preventive strategy for ulcerative colitis (UC), a chronic and debilitating inflammatory bowel disease.

Helmsley Charitable Trust Awards $3 Million Grant to Research Epithelial Healing in Crohn's Disease

Mount Sinai Health System — Fri, 13 Dec 2024 09:15:06 EST

he Helmsley Charitable Trust has awarded a grant of $3,035,566 to support groundbreaking research on Crohn's disease, to be led by a collaborative team of leading researchers across three institutions. Louis J. Cohen, MD, Assistant Professor of Medicine (Gastroenterology) at the Icahn School of Medicine at Mount Sinai; Parakkal Deepak, MD, Associate Professor of Medicine (Gastroenterology), Washington University School of Medicine; and Andres J. Yarur, MD, Associate Professor of Medicine (Gastroenterology), Cedars-Sinai Medical Center, will serve as co-investigators.

UTSW Research: Python Guts, Emergency Room Visits, and More

UT Southwestern Medical Center — Thu, 12 Dec 2024 21:00:25 EST

Regeneration insights from snake intestines / Understanding why cancer patients visit the ED / How burr holes affect transcranial direct current stimulation

Esophageal Cancer: Global Burden Intensifies, Calls for Urgent Action

Chinese Academy of Sciences — Wed, 11 Dec 2024 08:25:33 EST

A critical study sheds light on the growing global burden of esophageal cancer, outlining its significant impact and the imperative to identify the driving factors behind its increasing prevalence. This research presents a detailed analysis of the disease's incidence, mortality, disability-adjusted life years (DALYs) rates, and attributable risk factors, providing essential insights for the development of strategic cancer control measures on a global scale.

MD Anderson and AmMax Bio Announce Agreements to Advance Development of AMB-066 in Colorectal Cancer Patients with Minimal Residual Disease

University of Texas MD Anderson Cancer Center — Tue, 10 Dec 2024 08:00:59 EST

MD Anderson and AmMax Bio announced agreements to develop and advance AmMax's AMB-066 monoclonal antibody therapy for colorectal cancer with minimal residual disease.

Experts Debate Management of Patient with Gastroesophageal Reflux Symptoms

American College of Physicians (ACP) — Mon, 09 Dec 2024 17:00:00 EST

In a new Annals "Beyond the Guidelines" feature, two physicians, a primary care practitioner and a gastroenterologist, discuss the management of a patient with gastroesophageal reflux disease (GERD) symptoms. GERD is a common medical condition presenting with heartburn, regurgitation, cough, hoarseness and/or wheezing.

Heavy Metal Gut: A $1.9 million Study

University of New Mexico Comprehensive Cancer Center — Mon, 09 Dec 2024 11:30:41 EST

Julie In, PhD, received a $1.9 million grant from the National Institute of Environmental Health Sciences to study the impact of uranium on the cells that line the intestines.

Children's Hospital of Philadelphia Researchers Find Rotavirus Vaccine is Safe for Use in NICU Babies

Children's Hospital of Philadelphia — Mon, 09 Dec 2024 00:05:00 EST

Researchers found that transmission of rotavirus vaccine strains in a neonatal intensive care unit (NICU) is rare and without clinical consequences, strongly suggesting that giving the rotavirus vaccine to eligible infants during their hospitalization provides immune benefits that outweigh any risks. The findings could serve as the basis for a change in clinical practice.

UAlbany Chemists Develop Color-Changing Test for Rapid Salmonella Detection

University at Albany, State University of New York — Fri, 06 Dec 2024 13:55:19 EST

UAlbany researchers have developed a new method for fast-acting salmonella detection. The test employs a paper strip that changes color in the presence of the bacterial genome, enabling quick, easy and inexpensive screening for salmonella in food products.

Predictive Modeling Addresses Healthcare Disparities, Identifies at-Risk Patients Who May Need Stomach Cancer Screening

Cleveland Clinic — Wed, 04 Dec 2024 11:20:04 EST

Cleveland Clinic developed a predictive model to identify patients at risk of developing gastric (stomach) cancer who may benefit from stomach cancer screening. The model is designed to identify who might need regular upper endoscopies to screen for stomach cancer.

PCORI Awards UNC Researcher $14.4 Million to Study Emerging Medications for PIBD Patients

University of North Carolina School of Medicine — Tue, 03 Dec 2024 11:30:48 EST

The Patient-Centered Outcomes Research Institute (PCORI) announced the approval of funding totaling $14.4 million for UNC researcher to study new treatment options for pediatric inflammatory bowel diseases (PIBD). Michael D. Kappelman, MD, MPH, professor of pediatrics and epidemiology at the UNC School of Medicine, will serve as principal investigator.

Hackensack Meridian Pascack Valley Medical Group Welcomes Dr. Scott Lippe

Hackensack Meridian Pascack Valley Medical Center — Mon, 02 Dec 2024 11:35:12 EST

Pascack Valley Medical Group is pleased to announce Scott David Lippe, M.D. , board-certified gastroenterologist and internist, is joining the Pascack Valley Medical Center team.