Newswise Feature Channel: Personalized Medicine

Gillette Children's Leads the Way in Cerebral Palsy Care and Research

Gillette Children's — Fri, 28 Mar 2025 18:10:52 EST

NIH-Funded Trial Studies if Wearables Can Reduce the Need for Continuous Blood Thinners for Patients with Atrial Fibrillation

Northwestern Medicine — Thu, 27 Mar 2025 08:20:09 EST

Atrial fibrillation (AFib) is the most common type of heart arrhythmia impacting more than 5 million people in the United States, a number that is anticipated to reach 12.1 million by 2030. The heart rhythm condition is characterized by fast and irregular heartbeats from the upper chambers of the heart. People with AFib are at increased risk of stroke, heart failure, dementia, and premature death.

New AI Model Predicts Gene Variants' Effects on Specific Diseases

Cedars-Sinai — Mon, 24 Mar 2025 20:05:21 EST

Cedars-Sinai investigators have developed a novel artificial intelligence (AI) model, named DYNA, that accurately distinguishes harmful gene variations from harmless ones, potentially enhancing physicians' ability to diagnose diseases. The new tool could pave the way for more precise personalized medicine and targeted therapies.

The Right Moves to Rein in Fibrosis

Washington University in St. Louis — Mon, 24 Mar 2025 18:25:21 EST

Biomedical researchers at Washington University in St. Louis have decoded how mechanical forces drive cell behavior in fibrosis.

Mount Sinai Launches Center for Artificial Intelligence in Children's Health to Advance AI-Driven Outcomes in Children

Mount Sinai Health System — Mon, 24 Mar 2025 10:50:08 EST

New Center Aims to Accelerate AI Research and Personalized Treatment in Children's Health

Study: Suppressing Key Protein May Unlock Immunotherapy for Glioblastoma

Sylvester Comprehensive Cancer Center — Mon, 17 Mar 2025 12:05:00 EST

Glioblastoma is one of the toughest cancers to treat, but a new study suggests that suppressing a protein (ZNF638) triggers an antiviral immune response, making immune checkpoint inhibitors more effective. The discovery also identifies ZNF638 as a biomarker that could help personalize immunotherapy.

A Post-Treatment Blood Test Could Inform Future Cancer Therapy Decisions

Yale Cancer Center/Smilow Cancer Hospital — Mon, 17 Mar 2025 08:25:22 EST

A new study led by Dr. Roy Herbst, deputy director of Yale Cancer Center, found evidence to support the value of a tool that measures the presence of cancer-derived molecules in the blood of patients with lung cancer, years after their treatment.

New Insights Into Pediatric POTS: Tailored Therapies Improve Outcomes

Chinese Academy of Sciences — Mon, 10 Mar 2025 10:20:45 EST

A recent review has shed new light on the management of pediatric postural orthostatic tachycardia syndrome (POTS), a chronic condition causing dizziness, fatigue, and fainting, often triggered by standing. The study emphasizes the importance of personalized treatment strategies that focus on underlying mechanisms such as central hypovolemia, vascular dysfunction, and hyperadrenergic states. By tailoring therapies to the unique physiological and biochemical profiles of each patient, researchers are making strides in improving the outcomes for children affected by this challenging condition.

STIM1: The Cancer Shield Against Sorafenib Unmasked

Chinese Academy of Sciences — Tue, 04 Mar 2025 08:20:58 EST

A recent study unveils how stromal interaction molecule 1 (STIM1), a protein involved in calcium signaling, plays a pivotal role in the resistance of liver cancer to sorafenib, a key treatment for advanced hepatocellular carcinoma (HCC).

An Important Step Forward in Precision Oncology: New Genetic Tool Predicts Chemotherapy Side Effects Before Treatment Begins

Sbarro Health Research Organization (SHRO) — Wed, 26 Feb 2025 05:20:24 EST

A groundbreaking pharmacogenetic tool has been developed and validated to predict chemotherapy side effects based on a patient's genetic profile.

Physical Activity Boosts Mental Health in Women With Chronic Pelvic Pain Disorders

Mount Sinai Health System — Wed, 26 Feb 2025 02:00:00 EST

A new Mount Sinai study provides compelling evidence that exercise can significantly help the mental well-being of millions of women living with chronic pelvic pain disorders (CPPDs), such as endometriosis and uterine fibroids. The researchers at the Icahn School of Medicine at Mount Sinai found that activities like brisk walking or aerobic exercise can lead to measurable improvements in mental well-being, regardless of pain levels or history of anxiety or depressive disorders. Their findings were reported in the February 26 online issue of the Journal of Pain Research.

AI Model Predicts Hospital Stay Lengths for People with Learning Disabilities

Loughborough University — Tue, 25 Feb 2025 11:25:19 EST

A new artificial intelligence (AI) model has been developed to predict how long a person with a learning disability is likely to stay in hospital, offering valuable insights that could improve care and resource planning. Developed by computer scientists at Loughborough University as part of the 'DECODE' project, the model aims to tackle healthcare challenges faced by people with learning disabilities and multiple health conditions.

The International Headache Society (IHS) Raises the Standards for Migraine Prevention: A New Statement for More Ambitious Treatments

University of Miami Health System, Miller School of Medicine — Mon, 24 Feb 2025 19:15:45 EST

Migraine is much more than just a headache. It is a debilitating disease that can drastically impact the lives of those affected, limiting their ability to work, study, travel, spend time with family, and enjoy everyday moments.

Award-Winning Pharmaco-Geneticist Advances Drug Discovery and Development for Africans

University of the Witwatersrand, Johannesburg — Sun, 23 Feb 2025 11:35:45 EST

Masimirembwa, a Distinguished Professor at Wits University's Sydney Brenner Institute for Molecular Bioscience (SBIMB), received the award at a ceremony in California, USA, on 7 February. The PMWC Pioneer Award recognises Masimirembwa's groundbreaking work in pharmacogenomics, shedding light on how genetic differences influence drug responses across diverse populations.

More Precise Cancer Diagnosis Thanks to 3D Computed Tomography

Empa, Swiss Federal Laboratories for Materials Science and Technology — Thu, 20 Feb 2025 10:30:17 EST

Empa researchers have developed a new 3D tissue analysis for thyroid tumors. This special X-ray method uses artificial intelligence to enable more precise diagnoses without damaging the tissue removed. In the future, this examination method could also be used for other types of cancer and replace more complex procedures with simpler imaging methods.

Wesper Revolutionizes GLP-1 Sleep Apnea Screening and Enables Personalized Treatment

Wesper — Tue, 11 Feb 2025 08:30:42 EST

Wesper, a leader in advanced home sleep apnea testing (HSAT), is transforming how obesity and sleep apnea are managed by integrating groundbreaking biometric sleep data with metabolic health innovations. Following the FDA approval of GLP-1 receptor agonists for sleep apnea treatment, Wesper is working with hospitals and physicians to bridge the gap between obesity, diabetes, GLP-1 medications, and sleep apnea.

MD Anderson Research Highlights for February 10, 2025

University of Texas MD Anderson Cancer Center — Mon, 10 Feb 2025 17:00:00 EST

The University of Texas MD Anderson Cancer Center's Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson's world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. This issue includes studies to be presented this week at the 2025 American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium.

Cognitive abilities: mapping the impact of DNA modifications

Universite de Montreal — Tue, 04 Feb 2025 16:00:32 EST

A study explores how variations in the copy number of certain DNA segments can influence cognitive abilities and neurodevelopment.

Girish N. Nadkarni, MD, MPH, CPH, Named to Leadership Roles in AI and Digital Health at the Icahn School of Medicine at Mount Sinai

Mount Sinai Health System — Thu, 30 Jan 2025 09:00:29 EST

Girish N. Nadkarni, MD, MPH, CPH, an accomplished physician-scientist driving advances in artificial intelligence, has been appointed Chair of the Windreich Department of Artificial Intelligence and Human Health at the Icahn School of Medicine at Mount Sinai. The department is the first of its kind at a U.S. medical school, underscoring Mount Sinai's leadership in integrating artificial intelligence (AI) into health care. Dr. Nadkarni will also serve as Director of the Hasso Plattner Institute for Digital Health. The appointment marks the latest milestone in a series of progressive initiatives by Mount Sinai to harness and optimize artificial intelligence for transformative health care solutions. Recent developments include the launch of its state-of-the-art AI facility, designed to accelerate innovation and collaboration in translational medicine. Other developments include an exciting, soon-to-be-announced tool exclusively available to students at the Icahn School of Medicine at Mo

Moffitt Study Shows AI Boosts Efficacy of Cancer Treatment, But Doctors Remain Key

Moffitt Cancer Center — Thu, 30 Jan 2025 08:55:44 EST

A new study led by researchers from Moffitt Cancer Center, in collaboration with investigators from the University of Michigan, shows that artificial intelligence (AI) can help doctors make better decisions when treating cancer. However, it also highlights challenges in how doctors and AI work together. The study, published in Nature Communications, focused on AI-assisted radiotherapy for non-small cell lung cancer and hepatocellular carcinoma (liver cancer).