Newswise Feature Channel: Kidney Disease

Could a Key Protein Lead to New Therapies for Wilms Tumor?

Children's Hospital Los Angeles — Wed, 11 Dec 2024 16:15:48 EST

By most accounts, Wilms tumor treatment is a success story. For those younger than 20 who develop this most common form of childhood kidney cancer, five-year survival rates are over 90%.But for the roughly 15% of children with Wilms tumor who relapse--or for those whose cancer does not respond to treatment--survival rates plummet.

First Full Characterization of Kidney Microbiome Unlocks Potential to Prevent Kidney Stones

Cleveland Clinic — Wed, 11 Dec 2024 05:00:00 EST

Cleveland Clinic researchers have found definitive proof of a kidney microbiome that influences renal health and kidney stone formation, demonstrating that the urinary tract is not sterile and low levels of bacteria are normal. The Nature Communications publication describes the rigorous multi-pronged approach a team led by Aaron Miller, PhD, and Jose Agudelo, MD, used to identify and characterize the small bacterial community by combining preclinical, human and dish studies.

New Targets for Diabetic Kidney Disease Could Prevent End Stage Kidney Failure

University of Bristol — Tue, 10 Dec 2024 06:25:28 EST

New potential therapeutic targets have been identified for diabetic kidney disease (DKD) - the leading cause of kidney failure in the world - that could see patients treated with new gene and drug therapies preventing the disease's progression into end stage kidney failure.

American Society of Nephrology Celebrates New Legislation to Expand Support for Living Donors

American Society of Nephrology (ASN) — Wed, 04 Dec 2024 14:20:29 EST

The American Society of Nephrology (ASN) celebrates the introduction of the Expanding Support for Living Donors Act of 2024, legislation that would bolster and expand support for living organ donors.

Enzyme Identified as New Therapeutic Target for "Cold" Tumors

Michigan Medicine - University of Michigan — Tue, 03 Dec 2024 12:50:50 EST

A study from the University of Michigan Health Rogel Cancer Center may have, at last, cracked the cold case of immunotherapy resistance.

PCORI Commits $156 Million to New Patient-Centered Health Research Studies

Patient-Centered Outcomes Research Institute (PCORI) — Tue, 03 Dec 2024 11:35:33 EST

The Patient-Centered Outcomes Research Institute (PCORI) has approved funding awards totaling more than $156 million for new patient-centered comparative clinical effectiveness research (CER), as well as research to improve methods and strengthen the science of engagement in CER.

American Society of Nephrology Welcomes New CMMI Model Aimed at Boosting Transplant Rates

American Society of Nephrology (ASN) — Wed, 27 Nov 2024 10:10:02 EST

The American Society of Nephrology (ASN) welcomes the final Increasing Organ Transplant Access (IOTA) model rule from the Centers for Medicare and Medicaid Innovation (CMMI).

Perfect Match: Woman Donates Lifesaving Kidney to Her Identical Twin

Cedars-Sinai — Tue, 26 Nov 2024 11:40:04 EST

Identical twins Linda Thomas and Karen Rodman, 56, have shared everything from the moment they were born. The Las Vegas residents live less than five miles from each other. They work together, carpool together, shop together. Their phone numbers would be identical, save for the last digit.

Nephrology Updates Fall 2024

Ann and Robert H. Lurie Children's Hospital of Chicago — Mon, 25 Nov 2024 12:00:12 EST

Providing information about dialysis and transplant to a patient in a non-urgent environment leads to better outcomes and improved patient care said Dr. Krissberg. There are a lot of moving parts when...

UChicago Medicine Expands in Hinsdale with New Salt Creek Clinic

University of Chicago Medical Center — Wed, 20 Nov 2024 14:00:24 EST

UChicago Medicine's current clinic on Salt Creek Lane in Hinsdale will close Nov. 21, and open across the street in a new, larger facility Dec. 2.

Denosumab Increases Risk of Emergently Treated Hypocalcemia in Advanced Chronic Kidney Disease

American College of Physicians (ACP) — Mon, 18 Nov 2024 17:00:00 EST

A target trial emulation evaluated the incidence of emergently treated hypoalcemia associated with denosumab by stage of chronic kidney disease (CKD) progression and presence of CKD-mineral and bone disorder (CKD-MBD).

Hackensack Meridian Mountainside Medical Center Nurse Wins Research Award at ACC Quality Summit

Hackensack Meridian Health (Mountainside Medical Center) — Fri, 15 Nov 2024 00:00:12 EST

Alyssa Stolarik, RN, BSN, clinical coordinator of Cardiology at Hackensack Meridian Health Mountainside Medical Center, received the Second Best Research Poster Award at the American College of Cardiology (ACC) Quality Summit held in San Antonio, Texas. Her work, titled "Improving Compliance with Post-PCI Creatinine," highlights significant advancements in the management of post-procedural care and patient outcomes. The research addresses the critical issue of acute kidney injury (AKI) post-percutaneous coronary intervention (PCI), demonstrating a marked reduction in risk-standardized AKI rates, which significantly surpasses national benchmarks.

UTSW Epidemiologist to Receive AHA Distinguished Scientist Award

UT Southwestern Medical Center — Wed, 13 Nov 2024 14:05:05 EST

Jiang He, M.D., Ph.D., Professor and Chair Designate of Epidemiology in the Peter O'Donnell Jr. School of Public Health at UT Southwestern Medical Center, is a 2024 recipient of the American Heart Association's (AHA) highest commendation, the Distinguished Scientist award. The honor recognizes Dr. He's prolific research on reducing the risks of cardiometabolic diseases, including heart disease, stroke, obesity, Type 2 diabetes, hypertension, dyslipidemia, and chronic kidney disease.

Johns Hopkins Researchers Use Electronic Diagnostic Model to Predict Acute Interstitial Nephritis (AIN) in Patients

Johns Hopkins Medicine — Tue, 12 Nov 2024 11:00:05 EST

Researchers from both Johns Hopkins Medicine and Yale University collaborated on the development and application of a diagnostic model to detect acute interstitial nephritis (AIN) in patients, which could have a lasting impact on getting patients diagnosed earlier

Ochsner Transplant Institute Among Site Collaborators in New England Journal of Medicine HIV-to-HIV Kidney Transplant Study

Ochsner Health — Mon, 11 Nov 2024 12:35:58 EST

The article, Safety of Kidney Transplantation from Donors with HIV, details findings supporting HIV-to-HIV kidney transplants as safe and just as effective as those using organs from donors without HIV.

Study: Women, Girls at Lower Risk of Acute Kidney Injury

Yale School of Medicine — Thu, 31 Oct 2024 09:45:38 EST

Fasting-Mimicking Diet Restores Kidney Function in Study

Children's Hospital Los Angeles — Wed, 30 Oct 2024 14:25:03 EST

In patients with chronic kidney disease, the loss of podocytes--part of the kidney's glomerular filtration barrier--causes irreversible disease progression. So far, physicians and researchers have found no way to effectively prevent podocyte damage, loss, and deterioration leading to end-stage kidney disease.

Advances in Minimally Invasive Kidney Stone Surgery

Mayo Clinic — Wed, 30 Oct 2024 10:50:50 EST

Most small kidney stones can pass on their own. However, kidney stones that are too large to pass on their own or cause bleeding, kidney damage or ongoing urinary tract infections may require surgical treatment. Dr. Aaron Potretzke, a Mayo Clinic urologist in Rochester, Minnesota, explains some of the different surgical options for removing kidney stones.

Avancos na cirurgia minimamente invasiva de calculo renal

Mayo Clinic — Wed, 30 Oct 2024 10:50:37 EST

A maioria dos calculos renais podem ser expelidos por conta propria. "No entanto, os calculos renais que sao grandes demais para serem expelidos sozinhos ou que causam sangramento, danos nos rins ou infeccoes urinarias recorrentes podem exigir tratamento cirurgico." O Dr. Aaron Potretzke, urologista da Mayo Clinic em Rochester, Minnesota, explica algumas das opcoes cirurgicas para remover os calculos renais.

Avances en la cirugia minimamente invasiva de calculos renales

Mayo Clinic — Wed, 30 Oct 2024 10:40:54 EST

La mayoria de los calculos renales pueden ser expulsados por su cuenta. "Sin embargo, los calculos renales que son demasiado grandes para ser expulsados por si solos o que causan sangrado, dano renal o infecciones urinarias recurrentes pueden requerir tratamiento quirurgico." El Dr. Aaron Potretzke, urologo en Mayo Clinic en Rochester, Minnesota, explica algunas de las opciones quirurgicas para extirpar los calculos renales.