Newswise Feature Channel: Alzheimer's and Dementia

Declining senses can impact mental health and loneliness in aging adults

University of Chicago Medical Center — Thu, 22 Aug 2024 18:05:27 EST

UChicago researchers found that people who develop sensory disabilities with age tend to have worse mental health, and that different types of sensory disability are associated with different aspects of mental health.

UC Irvine discovery of 'item memory' brain cells offers new Alzheimer's treatment target

University of California, Irvine — Wed, 21 Aug 2024 11:05:50 EST

Researchers from the University of California, Irvine have discovered the neurons responsible for "item memory," deepening our understanding of how the brain stores and retrieves the details of "what" happened and offering a new target for treating Alzheimer's disease.

NIH Awards $6.9 Million to Advance Potential Alzheimer's Disease Treatment

University of California San Diego — Tue, 20 Aug 2024 05:00:18 EST

Researchers from UC San Diego are working on a new treatment for Alzheimer's that targets tau - a type of protein in the brain that helps cells retain their stability and structure.

Same person. Different place. Twice the odds of a dementia diagnosis.

Michigan Medicine - University of Michigan — Fri, 16 Aug 2024 07:00:00 EST

With new medications on the market or in the works for Alzheimer's disease and other kinds of dementia, a new study suggests that getting the diagnosis needed to access these new treatments may depend on where you live.

Mild cognitive impairment could be going unreported in rural areas of West Michigan, study suggests

Michigan State University — Thu, 15 Aug 2024 10:05:16 EST

Researchers from Michigan State University and Corewell Health used de-identified electronic health records of more than 1.5 million patients to analyze incidence rates and risk factors of mild cognitive impairment, or MCI, in rural and urban areas in West Michigan. They are the first researchers in the state to use this technique.

New research led by UTHealth Houston sheds light on the behavioral and psychological symptoms of Alzheimer's disease and related dementias

University of Texas Health Science Center at Houston — Thu, 15 Aug 2024 08:05:19 EST

A study offering insights into understanding and managing the behavioral and psychological symptoms of Alzheimer's disease and related dementias led by a team of UTHealth Houston researchers has been published in Alzheimer's & Dementia, the journal of the Alzheimer's Association.

Patterns of Intelligence

Cedars-Sinai — Wed, 14 Aug 2024 16:05:31 EST

The coordinated activity of brain cells, like birds flying in formation, helps us behave intelligently in new situations, according to a study led by Cedars-Sinai investigators.

Do People with High Blood Pressure Have a Higher Risk of Alzheimer's Disease?

American Academy of Neurology (AAN) — Wed, 14 Aug 2024 16:00:00 EST

People 60 and older with untreated high blood pressure may have an increased risk of Alzheimer's disease compared to both people who have been or are being treated for high blood pressure as well as people without the chronic condition. The new research, a meta-analysis, is published in the August 14, 2024, online issue of Neurology(r), the medical journal of the American Academy of Neurology. These results do not prove that untreated high blood pressure causes Alzheimer's disease, they only show an association.

IU-led early-onset Alzheimer's study expands globally

Indiana University — Tue, 13 Aug 2024 07:30:43 EST

The largest study of early-onset Alzheimer's disease in the United States is expanding internationally, becoming one of the largest programs of its kind in the world.

Taking a 'One in a Million' Shot to Tackle Dopamine-Linked Brain Disorders

Florida Atlantic University — Mon, 12 Aug 2024 08:30:05 EST

With the help of a tiny, transparent worm called Caenorhabditis elegans, researchers have identified novel players in dopamine signaling by taking advantage of a powerful platform generated via the Million Mutation Project for the rapid identification of mutant genes based on their functional impact.

Mild cognitive impairment could be going unreported in rural areas of West Michigan, study suggests

Corewell Health — Mon, 12 Aug 2024 07:00:00 EST

Corewell Health(tm) and Michigan State University researchers are the first in the state to use de-identified electronic health records of more than 1.5 million patients to analyze incidence rates and risk factors of mild cognitive impairment, or MCI, in rural and urban areas in West Michigan.

Low magnesium levels increase disease risk, new study shows

University of South Australia — Sun, 11 Aug 2024 19:05:40 EST

A new Australian study has identified why a diet rich in magnesium is so important for our health, reducing the risk of DNA damage and chronic degenerative disorders.

Molecule restores cognition, memory in Alzheimer's disease model mice

University of California, Los Angeles (UCLA), Health Sciences — Wed, 07 Aug 2024 17:05:43 EST

In a new study, a molecule identified and synthesized by UCLA Health researchers was shown to restore cognitive functions in mice with symptoms of Alzheimer's disease by effectively jumpstarting the brain's memory circuitry.

In Parkinson's, Dementia May Occur Less Often, or Later, than Thought

American Academy of Neurology (AAN) — Wed, 07 Aug 2024 16:00:00 EST

There's some good news for people with Parkinson's disease: The risk of developing dementia may be lower than previously thought, or dementia may occur later in the course of the disease than previously reported, according to a study published in the August 7, 2024, online issue of Neurology(r), the medical journal of the American Academy of Neurology.

Expert Available: Does Your Morning Java Protect Against Dementia?

George Washington University — Wed, 07 Aug 2024 12:00:18 EST

A new study suggests drinking two or more cups of coffee per day was associated with a nearly 30% decreased risk of dementia over a 7-year period. Moderate tea drinking was also associated with a... ...

A Better Understanding of DNA Unpacking

Lawrence Berkeley National Laboratory — Tue, 06 Aug 2024 16:30:46 EST

Researchers now have a better understanding of the protein complex that creates access to packed DNA, TIP60. Knowing the detailed structure and behavior of TIP60 could provide insight into different diseases where the protein complex plays a role, such as Alzheimer's and various cancers.

UC Irvine-led team reveals how TREM2 genetic mutation affects late-onset Alzheimer's

University of California, Irvine — Tue, 06 Aug 2024 14:05:23 EST

Researchers led by the University of California, Irvine have discovered how the TREM2 R47H genetic mutation causes certain brain areas to develop abnormal protein clumps, called beta-amyloid plaques, associated with late-onset Alzheimer's disease.

Researchers Discover Cholesterol Drug's Potential as Treatment for Alzheimer's, Other Dementia

University of Arkansas for Medical Sciences — Tue, 06 Aug 2024 11:05:43 EST

Researchers from the University of Arkansas for Medical Sciences (UAMS) have discovered that an FDA-approved cholesterol drug holds the potential to disrupt the progression of Alzheimer's disease and other forms of dementia.

Can targeted therapies be applied to patients with Alzheimer's?

University of Utah — Mon, 05 Aug 2024 16:05:27 EST

University of Utah researchers discover potential treatments that target amyloid beta plaques on the brain that lead to dementia in patients with Alzheimer's disease.

Researchers receive 9.5 million grant to study relationship between polyphenol intake, Alzheimer's prevention, and the brain-gut-microbiome system

University of California, Los Angeles (UCLA), Health Sciences — Mon, 05 Aug 2024 12:05:48 EST

UCLA Health researchers, in collaboration with researchers from the Republic of Ireland and Northern Ireland, have received $9.5 million award from the National Institutes of Health (NIH) with support from European funding agencies -- The Science Foundation Ireland (SFI) and the Public Health Agency Health & Social Care (HSC) -- to study the effects of polyphenols on cognitive health and the brain-gut microbiome system.