Newswise — One of the largest global gatherings of cancer experts begins Friday in San Diego, at the annual meeting of the American Association of Cancer Research (AACR).
The five-day session (April 5-10), themed as “Inspiring Science. Fueling Progress. Revolutionizing Care,” will include new findings from Yale Cancer Center researchers and witness the leadership of AACR transfer to Yale Cancer Center’s Patricia LoRusso, DO, PhD (h), who will serve as president of the 58,000-person AACR for 2024-25. LoRusso leads early clinical trials and cancer drug development at Yale Cancer Center and is an internationally recognized leader in trial research.
Other Yale Cancer Center leaders attending the meeting include YCC deputy director and Yale School of Medicine assistant dean for translation research, Roy Herbst, MD, PhD. On Tuesday April 9, he will lead a press conference on liquid biopsy for early detection and personalized cancer vaccines.
In addition, YCC researchers will present their new cancer research findings. In the videos above, a few of the presenting YCC researchers offer their key study takeaways and the significance for patients and oncologists. Click the links below for more information on their studies.
- In the video above, Yang Yang-Hartwich, PhD discusses her research on the identification of SORL1 as a key regulator of chemoresistance in ovarian cancer. She says that when treating ovarian cancer cells with chemotherapy, the surviving cells that are left can have higher levels of the gene, SORL1, which has been found to aid in the cell’s resistance to chemotherapy.
- Ola Adadelokun and Caroline Johnson, PhD discuss in the video above their research on sex differences in cancer stemness among individuals with early onset colorectal cancer. They say their study highlights sex-specific influences on the cellular level during the progression of early onset colorectal cancer.
- Jeffrey Townsend, PhD discusses in the above video his AACR presentation, “Tobacco smoke alters the adaptive landscape of lung adenocarcinoma and influences the strength of epistatic interactions.” His study showed how smoking increases the mutation rate of lung cells and they also found clinically relevant differences in mutations between smoker and never-smoker cancers.
Click here for a full list of YCC presentations.
MEDIA CONTACT
Register for reporter access to contact detailsRELEVANT EXPERTS
Patricia LoRusso
Professor of Medicine (Medical Oncology); Chief, Experimental Therapeutics; Associate Cancer Center Director, Experimental Therapeutics
Yale Cancer Center/Smilow Cancer HospitalRoy Herbst
Ensign Professor of Medicine (Medical Oncology) and Professor of Pharmacology; Deputy Director, Yale Cancer Center; Chief of Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital; Assistant Dean for Translational Research, Yale School of Medicine; Director, Center for Thoracic Cancers, Yale Cancer Center and Smilow Cancer Hospital; Co-Principal Investigator and Community Outreach Co-Leader, Cancer Disparities Firewall Project
Yale Cancer Center/Smilow Cancer Hospital